Gene name: DPB4
Reference locus (S288C): YDR121W
Gene biotype: protein_coding
Description: Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex; involved in both chromosomal DNA replication and inheritance of telomeric silencing; stabilizes the interaction of Pol epsilon with primer-template DNA, positively affecting the processivity of the polymerase and exonuclease activities of Pol epsilon; interacts with extranucleosomal DNA and acts as anchor point for ISW2 complex that retains its position on DNA during nucleosome mobilization
Top 10 interactors (score): ITC1 (0.999); DPB3 (0.999); POL2 (0.999); DLS1 (0.999); DPB2 (0.999); POL31 (0.998); ISW2 (0.997); HAP5 (0.995); POL3 (0.995); CDC45 (0.994); POL1 (0.993); POL12 (0.992); REV3 (0.991); NCB2 (0.99); PRI2 (0.987); MCM7 (0.986); PRI1 (0.985); MCM5 (0.98); ISW1 (0.98); MCM6 (0.979)
Homologues (species, bitscore): POLE3 (Homo sapiens, 52.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:664527-665120:+ | gene-YDR121W_AKU4011 | rna-NM_001180429.3_AKU4011 | cds-NP_010406.3_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:459758-460348:- | gene-YDR121W_BG1 | rna-NM_001180429.3_BG1 | cds-NP_010406.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:696587-697180:+ | gene-YDR121W_Bruggeman | rna-NM_001180429.3_Bruggeman | cds-NP_010406.3_Bruggeman | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:683324-683917:+ | gene-YDR121W_CAT1 | rna-NM_001180429.3_CAT1 | cds-NP_010406.3_CAT1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:655565-656158:+ | gene-YDR121W_CBS1585 | rna-NM_001180429.3_CBS1585 | cds-NP_010406.3_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:681448-682038:+ | gene-YDR121W_CBS436 | rna-NM_001180429.3_CBS436 | cds-NP_010406.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:651917-652510:+ | gene-YDR121W_CBS6412 | rna-NM_001180429.3_CBS6412 | cds-NP_010406.3_CBS6412 | 98.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:680893-681486:+ | gene-YDR121W_CBS6413 | rna-NM_001180429.3_CBS6413 | cds-NP_010406.3_CBS6413 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:686033-686626:+ | gene-YDR121W_CENPK1137D | rna-NM_001180429.3_CENPK1137D | cds-NP_010406.3_CENPK1137D | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:666293-666886:+ | gene-YDR121W_EthanolRed | rna-NM_001180429.3_EthanolRed | cds-NP_010406.3_EthanolRed | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:673087-673680:+ | gene-YDR121W_FaliES1 | rna-NM_001180429.3_FaliES1 | cds-NP_010406.3_FaliES1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000002.1:25207-25797:+ | gene-YDR121W_JAY291 | rna-NM_001180429.3_JAY291 | cds-NP_010406.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:682511-683104:+ | gene-YDR121W_MUCL30387 | rna-NM_001180429.3_MUCL30387 | cds-NP_010406.3_MUCL30387 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:671530-672123:+ | gene-YDR121W_MUCL30388 | rna-NM_001180429.3_MUCL30388 | cds-NP_010406.3_MUCL30388 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:656906-657499:+ | gene-YDR121W_MUCL39482 | rna-NM_001180429.3_MUCL39482 | cds-NP_010406.3_MUCL39482 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:594873-595466:+ | gene-YDR121W_MUCL42920 | rna-NM_001180429.3_MUCL42920 | cds-NP_010406.3_MUCL42920 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:693508-694098:+ | gene-YDR121W_NCIM3186 | rna-NM_001180429.3_NCIM3186 | cds-NP_010406.3_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:656311-656904:+ | gene-YDR121W_NCYC1407 | rna-NM_001180429.3_NCYC1407 | cds-NP_010406.3_NCYC1407 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:675635-676225:+ | gene-YDR121W_PE2H3 | rna-NM_001180429.3_PE2H3 | cds-NP_010406.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:674940-675530:+ | gene-YDR121W_PE2H4 | rna-NM_001180429.3_PE2H4 | cds-NP_010406.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:693585-694175:+ | gene-YDR121W_S288C | rna-NM_001180429.3_S288C | cds-NP_010406.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:42251-42841:+ | gene-YDR121W_SA1 | rna-NM_001180429.3_SA1 | cds-NP_010406.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:672609-673202:+ | gene-YDR121W_ThermosaccDry | rna-NM_001180429.3_ThermosaccDry | cds-NP_010406.3_ThermosaccDry | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:685949-686539:+ | gene-YDR121W_VR1 | rna-NM_001180429.3_VR1 | cds-NP_010406.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:670195-670788:+ | gene-YDR121W_ZTW1 | rna-NM_001180429.3_ZTW1 | cds-NP_010406.3_ZTW1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:674623-675213:+ | gene-YDR121W_Sparadoxus | rna-NM_001180429.3_Sparadoxus | cds-NP_010406.3_Sparadoxus | 87.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |