Gene name: DPB3
Reference locus (S288C): YBR278W
Gene biotype: protein_coding
Description: Third-largest subunit of DNA polymerase II (DNA polymerase epsilon); required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; stabilizes the interaction of Pol epsilon with primer-template DNA, positively affecting the processivity of the polymerase and exonuclease activities of Pol epsilon; mRNA abundance peaks at the G1/S boundary of the cell cycle; DPB3 has a paralog, DLS1, that arose from the whole genome duplication
Top 10 interactors (score): POL2 (0.999); DPB2 (0.999); DPB4 (0.999); POL3 (0.992); POL31 (0.991); CDC45 (0.983); POL32 (0.982); POL1 (0.981); REV3 (0.98); POL12 (0.979); PRI1 (0.978); PRI2 (0.977); MCM2 (0.966); REV7 (0.954); MCM10 (0.95); MCM5 (0.948); MCM4 (0.943); MCM6 (0.937); ORC4 (0.929); MCM3 (0.926)
Homologues (species, bitscore): Y53F4B.3 (Caenorhabditis elegans, 56.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:744573-745178:+ | gene-YBR278W_AKU4011 | rna-NM_001178626.1_AKU4011 | cds-NP_009837.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:115589-116194:+ | gene-YBR278W_BG1 | rna-NM_001178626.1_BG1 | cds-NP_009837.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:745728-746333:+ | gene-YBR278W_Bruggeman | rna-NM_001178626.1_Bruggeman | cds-NP_009837.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:749453-750058:+ | gene-YBR278W_CAT1 | rna-NM_001178626.1_CAT1 | cds-NP_009837.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:736139-736744:+ | gene-YBR278W_CBS1585 | rna-NM_001178626.1_CBS1585 | cds-NP_009837.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:742576-743181:+ | gene-YBR278W_CBS436 | rna-NM_001178626.1_CBS436 | cds-NP_009837.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:830754-831359:+ | gene-YBR278W_CBS6412 | rna-NM_001178626.1_CBS6412 | cds-NP_009837.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:742187-742792:+ | gene-YBR278W_CBS6413 | rna-NM_001178626.1_CBS6413 | cds-NP_009837.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:754194-754799:+ | gene-YBR278W_CENPK1137D | rna-NM_001178626.1_CENPK1137D | cds-NP_009837.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:867608-868213:+ | gene-YBR278W_EthanolRed | rna-NM_001178626.1_EthanolRed | cds-NP_009837.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:760955-761560:+ | gene-YBR278W_FaliES1 | rna-NM_001178626.1_FaliES1 | cds-NP_009837.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:42508-43113:- | gene-YBR278W_JAY291 | rna-NM_001178626.1_JAY291 | cds-NP_009837.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:747771-748376:+ | gene-YBR278W_MUCL30387 | rna-NM_001178626.1_MUCL30387 | cds-NP_009837.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:764853-765458:+ | gene-YBR278W_MUCL30388 | rna-NM_001178626.1_MUCL30388 | cds-NP_009837.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:734446-735051:+ | gene-YBR278W_MUCL39482 | rna-NM_001178626.1_MUCL39482 | cds-NP_009837.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:744315-744920:+ | gene-YBR278W_MUCL42920 | rna-NM_001178626.1_MUCL42920 | cds-NP_009837.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:760091-760696:+ | gene-YBR278W_NCIM3186 | rna-NM_001178626.1_NCIM3186 | cds-NP_009837.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:736335-736940:+ | gene-YBR278W_NCYC1407 | rna-NM_001178626.1_NCYC1407 | cds-NP_009837.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:759454-760059:+ | gene-YBR278W_PE2H3 | rna-NM_001178626.1_PE2H3 | cds-NP_009837.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:757130-757735:+ | gene-YBR278W_PE2H4 | rna-NM_001178626.1_PE2H4 | cds-NP_009837.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:760294-760899:+ | gene-YBR278W_S288C | rna-NM_001178626.1_S288C | cds-NP_009837.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:115409-116014:+ | gene-YBR278W_SA1 | rna-NM_001178626.1_SA1 | cds-NP_009837.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:759947-760552:+ | gene-YBR278W_ThermosaccDry | rna-NM_001178626.1_ThermosaccDry | cds-NP_009837.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:740154-740759:+ | gene-YBR278W_VR1 | rna-NM_001178626.1_VR1 | cds-NP_009837.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:732791-733396:+ | gene-YBR278W_ZTW1 | rna-NM_001178626.1_ZTW1 | cds-NP_009837.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:776699-777301:+ | gene-YBR278W_Sparadoxus | rna-NM_001178626.1_Sparadoxus | cds-NP_009837.1_Sparadoxus | 85.9 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |