Gene name: DPB2
Reference locus (S288C): YPR175W
Gene biotype: protein_coding
Description: Second largest subunit of DNA polymerase II (DNA polymerase epsilon); required for maintenance of fidelity of chromosomal replication; essential motif in C-terminus is required for formation of the four-subunit Pol epsilon; expression peaks at the G1/S phase boundary; Cdc28p substrate
Top 10 interactors (score): PSF1 (0.999); DPB4 (0.999); PSF2 (0.999); MCM3 (0.999); POL1 (0.999); POL3 (0.999); PRI2 (0.999); MCM5 (0.999); MCM7 (0.999); POL31 (0.999); MCM6 (0.999); MCM2 (0.999); CDC45 (0.999); POL12 (0.999); PRI1 (0.999); MCM4 (0.999); POL2 (0.999); DPB3 (0.999); ORC4 (0.998); PSF3 (0.998)
Homologues (species, bitscore): POLE2 (Homo sapiens, 178.3); Pole2 (Mus musculus, 188.7); pole2 (Danio rerio, 144.1); pole2 (Xenopus tropicalis, 178.7); DNApol-epsilon58 (Drosophila melanogaster, 146.0); pole-2 (Caenorhabditis elegans, 123.6); DPB2 (Arabidopsis thaliana, 174.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:843253-845322:+ | gene-YPR175W_AKU4011 | rna-NM_001184272.1_AKU4011 | cds-NP_015501.2_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:52388-54457:- | gene-YPR175W_BG1 | rna-NM_001184272.1_BG1 | cds-NP_015501.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:924537-926606:+ | gene-YPR175W_Bruggeman | rna-NM_001184272.1_Bruggeman | cds-NP_015501.2_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:966593-968662:+ | gene-YPR175W_CAT1 | rna-NM_001184272.1_CAT1 | cds-NP_015501.2_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:848055-850124:+ | gene-YPR175W_CBS1585 | rna-NM_001184272.1_CBS1585 | cds-NP_015501.2_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:861601-863670:+ | gene-YPR175W_CBS436 | rna-NM_001184272.1_CBS436 | cds-NP_015501.2_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:849839-851908:+ | gene-YPR175W_CBS6412 | rna-NM_001184272.1_CBS6412 | cds-NP_015501.2_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:844983-847052:+ | gene-YPR175W_CBS6413 | rna-NM_001184272.1_CBS6413 | cds-NP_015501.2_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:889059-891128:+ | gene-YPR175W_CENPK1137D | rna-NM_001184272.1_CENPK1137D | cds-NP_015501.2_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1165015-1167084:+ | gene-YPR175W_EthanolRed | rna-NM_001184272.1_EthanolRed | cds-NP_015501.2_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:845088-847157:+ | gene-YPR175W_FaliES1 | rna-NM_001184272.1_FaliES1 | cds-NP_015501.2_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000081.1:32379-34448:+ | gene-YPR175W_JAY291 | rna-NM_001184272.1_JAY291 | cds-NP_015501.2_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:891783-893852:+ | gene-YPR175W_MUCL30387 | rna-NM_001184272.1_MUCL30387 | cds-NP_015501.2_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:865912-867981:+ | gene-YPR175W_MUCL30388 | rna-NM_001184272.1_MUCL30388 | cds-NP_015501.2_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:840255-842324:+ | gene-YPR175W_MUCL39482 | rna-NM_001184272.1_MUCL39482 | cds-NP_015501.2_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:904725-906794:+ | gene-YPR175W_MUCL42920 | rna-NM_001184272.1_MUCL42920 | cds-NP_015501.2_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:888957-891026:+ | gene-YPR175W_NCIM3186 | rna-NM_001184272.1_NCIM3186 | cds-NP_015501.2_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:848616-850685:+ | gene-YPR175W_NCYC1407 | rna-NM_001184272.1_NCYC1407 | cds-NP_015501.2_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:860903-862972:+ | gene-YPR175W_PE2H3 | rna-NM_001184272.1_PE2H3 | cds-NP_015501.2_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:860551-862620:+ | gene-YPR175W_PE2H4 | rna-NM_001184272.1_PE2H4 | cds-NP_015501.2_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:888974-891043:+ | gene-YPR175W_S288C | rna-NM_001184272.1_S288C | cds-NP_015501.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000060.1:34769-36838:- | gene-YPR175W_SA1 | rna-NM_001184272.1_SA1 | cds-NP_015501.2_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:844776-846845:+ | gene-YPR175W_ThermosaccDry | rna-NM_001184272.1_ThermosaccDry | cds-NP_015501.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:872558-874627:+ | gene-YPR175W_VR1 | rna-NM_001184272.1_VR1 | cds-NP_015501.2_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:847325-849394:+ | gene-YPR175W_ZTW1 | rna-NM_001184272.1_ZTW1 | cds-NP_015501.2_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:849394-851466:+ | gene-YPR175W_Sparadoxus | rna-NM_001184272.1_Sparadoxus | cds-NP_015501.2_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |