Gene name: DOT6
Reference locus (S288C): YER088C
Gene biotype: protein_coding
Description: Transcriptional regulatory protein DOT6; Protein involved in rRNA and ribosome biogenesis; activated in stochastic pulses of nuclear localization; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation; relative distribution to the nucleus increases upon DNA replication stress; Belongs to the DOT6 family
Top 10 interactors (score): RPD3 (0.98); RXT3 (0.969); STB3 (0.951); CTI6 (0.949); TOD6 (0.945); SDS3 (0.939); SIN3 (0.935); UME6 (0.925); ASH1 (0.925); PHO23 (0.924); RXT2 (0.908); UME1 (0.906); SET3 (0.903); SIF2 (0.9); SNT1 (0.9); SAP30 (0.9); HOS2 (0.9); TOS4 (0.9); DEP1 (0.9); SCH9 (0.822)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:326949-328961:- | gene-YER088C_AKU4011 | rna-NM_001178979.3_AKU4011 | cds-NP_011012.3_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:96837-98849:+ | gene-YER088C_BG1 | rna-NM_001178979.3_BG1 | cds-NP_011012.3_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:336549-338561:- | gene-YER088C_Bruggeman | rna-NM_001178979.3_Bruggeman | cds-NP_011012.3_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:330900-332912:- | gene-YER088C_CAT1 | rna-NM_001178979.3_CAT1 | cds-NP_011012.3_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:326814-328826:- | gene-YER088C_CBS1585 | rna-NM_001178979.3_CBS1585 | cds-NP_011012.3_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:328956-330968:- | gene-YER088C_CBS436 | rna-NM_001178979.3_CBS436 | cds-NP_011012.3_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:326270-328282:- | gene-YER088C_CBS6412 | rna-NM_001178979.3_CBS6412 | cds-NP_011012.3_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:332260-334272:- | gene-YER088C_CBS6413 | rna-NM_001178979.3_CBS6413 | cds-NP_011012.3_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:331089-333101:- | gene-YER088C_CENPK1137D | rna-NM_001178979.3_CENPK1137D | cds-NP_011012.3_CENPK1137D | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:327292-329304:- | gene-YER088C_EthanolRed | rna-NM_001178979.3_EthanolRed | cds-NP_011012.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:327737-329749:- | gene-YER088C_FaliES1 | rna-NM_001178979.3_FaliES1 | cds-NP_011012.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000153.1:42797-44809:- | gene-YER088C_JAY291 | rna-NM_001178979.3_JAY291 | cds-NP_011012.3_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:331944-333956:- | gene-YER088C_MUCL30387 | rna-NM_001178979.3_MUCL30387 | cds-NP_011012.3_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:327615-329627:- | gene-YER088C_MUCL30388 | rna-NM_001178979.3_MUCL30388 | cds-NP_011012.3_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:325838-327850:- | gene-YER088C_MUCL39482 | rna-NM_001178979.3_MUCL39482 | cds-NP_011012.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:333082-335094:- | gene-YER088C_MUCL42920 | rna-NM_001178979.3_MUCL42920 | cds-NP_011012.3_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:333175-335187:- | gene-YER088C_NCIM3186 | rna-NM_001178979.3_NCIM3186 | cds-NP_011012.3_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:330901-332913:- | gene-YER088C_NCYC1407 | rna-NM_001178979.3_NCYC1407 | cds-NP_011012.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:341551-343563:- | gene-YER088C_PE2H3 | rna-NM_001178979.3_PE2H3 | cds-NP_011012.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:331492-333504:- | gene-YER088C_PE2H4 | rna-NM_001178979.3_PE2H4 | cds-NP_011012.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:333176-335188:- | gene-YER088C_S288C | rna-NM_001178979.3_S288C | cds-NP_011012.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000023.1:42803-44815:- | gene-YER088C_SA1 | rna-NM_001178979.3_SA1 | cds-NP_011012.3_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:328534-330546:- | gene-YER088C_ThermosaccDry | rna-NM_001178979.3_ThermosaccDry | cds-NP_011012.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:329231-331243:- | gene-YER088C_VR1 | rna-NM_001178979.3_VR1 | cds-NP_011012.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:325695-327707:- | gene-YER088C_ZTW1 | rna-NM_001178979.3_ZTW1 | cds-NP_011012.3_ZTW1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:329110-331119:- | gene-YER088C_Sparadoxus | rna-NM_001178979.3_Sparadoxus | cds-NP_011012.3_Sparadoxus | 89.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |