Gene name: DON1
Reference locus (S288C): YDR273W
Gene biotype: protein_coding
Description: Donuts protein 1; Meiosis-specific component of the spindle pole body; subunit of the leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms a ring-like structure at the leading edge of the prospore membrane (PSM) during meiosis II; required for PSM growth and closure; DON1 has a paralog, CUE5, that arose from the whole genome
Top 10 interactors (score): CUE5 (0.918); ADY3 (0.819); SPO21 (0.813); SSP1 (0.766); SPO74 (0.765); SPO20 (0.763); MLH2 (0.749); SPO73 (0.717); SPO19 (0.711); REC104 (0.7); SPO16 (0.697); ZIP2 (0.695); MPC54 (0.674); SPO71 (0.67); SPO22 (0.619); HMRA2 (0.616); EMI1 (0.615); MSO1 (0.612); MSH5 (0.59); DIG2 (0.571)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:962474-963571:+ | gene-YDR273W_AKU4011 | rna-NM_001180581.3_AKU4011 | cds-NP_010559.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:168759-169856:- | gene-YDR273W_BG1 | rna-NM_001180581.3_BG1 | cds-NP_010559.3_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:988641-989738:+ | gene-YDR273W_Bruggeman | rna-NM_001180581.3_Bruggeman | cds-NP_010559.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:976485-977580:+ | gene-YDR273W_CAT1 | rna-NM_001180581.3_CAT1 | cds-NP_010559.3_CAT1 | 90.8 | 97.3 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:956919-958016:+ | gene-YDR273W_CBS1585 | rna-NM_001180581.3_CBS1585 | cds-NP_010559.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:974947-976044:+ | gene-YDR273W_CBS436 | rna-NM_001180581.3_CBS436 | cds-NP_010559.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:953602-954699:+ | gene-YDR273W_CBS6412 | rna-NM_001180581.3_CBS6412 | cds-NP_010559.3_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:974838-975935:+ | gene-YDR273W_CBS6413 | rna-NM_001180581.3_CBS6413 | cds-NP_010559.3_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1008819-1009916:+ | gene-YDR273W_CENPK1137D | rna-NM_001180581.3_CENPK1137D | cds-NP_010559.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:961020-962117:+ | gene-YDR273W_EthanolRed | rna-NM_001180581.3_EthanolRed | cds-NP_010559.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:969222-970319:+ | gene-YDR273W_FaliES1 | rna-NM_001180581.3_FaliES1 | cds-NP_010559.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000176.1:17475-18572:+ | gene-YDR273W_JAY291 | rna-NM_001180581.3_JAY291 | cds-NP_010559.3_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:974672-975769:+ | gene-YDR273W_MUCL30387 | rna-NM_001180581.3_MUCL30387 | cds-NP_010559.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:961986-963083:+ | gene-YDR273W_MUCL30388 | rna-NM_001180581.3_MUCL30388 | cds-NP_010559.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:948725-949822:+ | gene-YDR273W_MUCL39482 | rna-NM_001180581.3_MUCL39482 | cds-NP_010559.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:888717-889814:+ | gene-YDR273W_MUCL42920 | rna-NM_001180581.3_MUCL42920 | cds-NP_010559.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1010099-1011196:+ | gene-YDR273W_NCIM3186 | rna-NM_001180581.3_NCIM3186 | cds-NP_010559.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:962015-963112:+ | gene-YDR273W_NCYC1407 | rna-NM_001180581.3_NCYC1407 | cds-NP_010559.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:972642-973763:+ | gene-YDR273W_PE2H3 | rna-NM_001180581.3_PE2H3 | cds-NP_010559.3_PE2H3 | 96.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:977920-979017:+ | gene-YDR273W_PE2H4 | rna-NM_001180581.3_PE2H4 | cds-NP_010559.3_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1010176-1011273:+ | gene-YDR273W_S288C | rna-NM_001180581.3_S288C | cds-NP_010559.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000102.1:17801-18898:+ | gene-YDR273W_SA1 | rna-NM_001180581.3_SA1 | cds-NP_010559.3_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:973507-974604:+ | gene-YDR273W_ThermosaccDry | rna-NM_001180581.3_ThermosaccDry | cds-NP_010559.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:989100-990197:+ | gene-YDR273W_VR1 | rna-NM_001180581.3_VR1 | cds-NP_010559.3_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:17631-18728:+ | gene-YDR273W_ZTW1 | rna-NM_001180581.3_ZTW1 | cds-NP_010559.3_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:969933-971015:+ | gene-YDR273W_Sparadoxus | rna-NM_001180581.3_Sparadoxus | cds-NP_010559.3_Sparadoxus | 78.3 | 96.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |