DOC1 (YGL240W)


Gene profile

Gene name: DOC1
Reference locus (S288C): YGL240W
Gene biotype: protein_coding

Description: Anaphase-promoting complex subunit DOC1; Processivity factor; required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis; contains a conserved DOC1 homology domain; Belongs to the APC10 family

Top 10 interactors (score): APC5 (0.999); APC11 (0.999); APC2 (0.999); CDC26 (0.999); CDC16 (0.999); APC1 (0.999); APC4 (0.999); SWM1 (0.999); CDC23 (0.999); APC9 (0.999); CDC27 (0.999); MND2 (0.999); CDH1 (0.998); MAD2 (0.997); CDC20 (0.996); MAD3 (0.993); BUB1 (0.987); AMA1 (0.984); BUB3 (0.97); UBC11 (0.941)

Homologues (species, bitscore): ANAPC10 (Homo sapiens, 103.6); Anapc10 (Mus musculus, 104.0); anapc10 (Danio rerio, 102.1); anapc10 (Xenopus tropicalis, 99.8); APC10 (Drosophila melanogaster, 91.7); Y48G1C.12 (Caenorhabditis elegans, 91.3); APC10 (Arabidopsis thaliana, 99.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:50146-50898:+ gene-YGL240W_AKU4011 rna-NM_001181106.1_AKU4011 cds-NP_011274.2_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000175.1:42178-42930:+ gene-YGL240W_BG1 rna-NM_001181106.1_BG1 cds-NP_011274.2_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:50494-51246:+ gene-YGL240W_Bruggeman rna-NM_001181106.1_Bruggeman cds-NP_011274.2_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:48565-49317:+ gene-YGL240W_CAT1 rna-NM_001181106.1_CAT1 cds-NP_011274.2_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:54434-55186:+ gene-YGL240W_CBS1585 rna-NM_001181106.1_CBS1585 cds-NP_011274.2_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:49155-49907:+ gene-YGL240W_CBS436 rna-NM_001181106.1_CBS436 cds-NP_011274.2_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:42003-42755:+ gene-YGL240W_CBS6412 rna-NM_001181106.1_CBS6412 cds-NP_011274.2_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:48290-49042:+ gene-YGL240W_CBS6413 rna-NM_001181106.1_CBS6413 cds-NP_011274.2_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:48274-49026:+ gene-YGL240W_CENPK1137D rna-NM_001181106.1_CENPK1137D cds-NP_011274.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:41234-41986:+ gene-YGL240W_EthanolRed rna-NM_001181106.1_EthanolRed cds-NP_011274.2_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:41819-42571:+ gene-YGL240W_FaliES1 rna-NM_001181106.1_FaliES1 cds-NP_011274.2_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000079.1:24552-25304:- gene-YGL240W_JAY291 rna-NM_001181106.1_JAY291 cds-NP_011274.2_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:50432-51184:+ gene-YGL240W_MUCL30387 rna-NM_001181106.1_MUCL30387 cds-NP_011274.2_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:52584-53336:+ gene-YGL240W_MUCL30388 rna-NM_001181106.1_MUCL30388 cds-NP_011274.2_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:51031-51783:+ gene-YGL240W_MUCL39482 rna-NM_001181106.1_MUCL39482 cds-NP_011274.2_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:53917-54669:+ gene-YGL240W_MUCL42920 rna-NM_001181106.1_MUCL42920 cds-NP_011274.2_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:48613-49365:+ gene-YGL240W_NCIM3186 rna-NM_001181106.1_NCIM3186 cds-NP_011274.2_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:42791-43543:+ gene-YGL240W_NCYC1407 rna-NM_001181106.1_NCYC1407 cds-NP_011274.2_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:44644-45396:+ gene-YGL240W_PE2H3 rna-NM_001181106.1_PE2H3 cds-NP_011274.2_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:44192-44944:+ gene-YGL240W_PE2H4 rna-NM_001181106.1_PE2H4 cds-NP_011274.2_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:48613-49365:+ gene-YGL240W_S288C rna-NM_001181106.1_S288C cds-NP_011274.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000002.1:325968-326720:- gene-YGL240W_SA1 rna-NM_001181106.1_SA1 cds-NP_011274.2_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:42125-42877:+ gene-YGL240W_ThermosaccDry rna-NM_001181106.1_ThermosaccDry cds-NP_011274.2_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:49080-49832:+ gene-YGL240W_VR1 rna-NM_001181106.1_VR1 cds-NP_011274.2_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:41170-41922:+ gene-YGL240W_ZTW1 rna-NM_001181106.1_ZTW1 cds-NP_011274.2_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:49865-50617:+ gene-YGL240W_Sparadoxus rna-NM_001181106.1_Sparadoxus cds-NP_011274.2_Sparadoxus 88.7 100.0 Verified 1 1 1 False True False False False

Additional files