DNM1 (YLL001W)


Gene profile

Gene name: DNM1
Reference locus (S288C): YLL001W
Gene biotype: protein_coding

Description: Dynamin-related protein DNM1; Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and inheritance; self assembles on the cytoplasmic face of mitochondrial tubules at sites where division will occur; participates in endocytosis and regulates peroxisome fission along with Vps1p; mutants in the human ortholog DNM1L, which mediates mitochondrial fission, peroxisomal division, autophagy, and mitophagy, are associated with slowly progressive infantile encephalopathy

Top 10 interactors (score): ATG11 (0.999); MDV1 (0.999); FZO1 (0.999); FIS1 (0.999); CAF4 (0.996); MDM34 (0.971); EDE1 (0.961); APL3 (0.952); MDM10 (0.95); YNK1 (0.947); NUM1 (0.94); OMA1 (0.933); APM4 (0.926); CHC1 (0.923); MDM12 (0.915); INP53 (0.912); INP52 (0.912); UGO1 (0.909); MGM1 (0.903); PCP1 (0.896)

Homologues (species, bitscore): DNM1L (Homo sapiens, 627.5); Dnm1l (Mus musculus, 629.8); dnm1l (Danio rerio, 637.5); dnm1l (Xenopus tropicalis, 568.9); Drp1 (Drosophila melanogaster, 602.1); drp-1 (Caenorhabditis elegans, 589.3); DRP3A (Arabidopsis thaliana, 588.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:135647-137920:+ gene-YLL001W_AKU4011 rna-NM_001181821.1_AKU4011 cds-NP_013100.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:99079-101352:+ gene-YLL001W_BG1 rna-NM_001181821.1_BG1 cds-NP_013100.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:145764-148037:+ gene-YLL001W_Bruggeman rna-NM_001181821.1_Bruggeman cds-NP_013100.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:146560-148833:+ gene-YLL001W_CAT1 rna-NM_001181821.1_CAT1 cds-NP_013100.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:143246-145519:+ gene-YLL001W_CBS1585 rna-NM_001181821.1_CBS1585 cds-NP_013100.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:133612-135885:+ gene-YLL001W_CBS436 rna-NM_001181821.1_CBS436 cds-NP_013100.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:142018-144291:+ gene-YLL001W_CBS6412 rna-NM_001181821.1_CBS6412 cds-NP_013100.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:143512-145785:+ gene-YLL001W_CBS6413 rna-NM_001181821.1_CBS6413 cds-NP_013100.1_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:132931-135204:+ gene-YLL001W_CENPK1137D rna-NM_001181821.1_CENPK1137D cds-NP_013100.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:135668-137941:+ gene-YLL001W_EthanolRed rna-NM_001181821.1_EthanolRed cds-NP_013100.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:135239-137512:+ gene-YLL001W_FaliES1 rna-NM_001181821.1_FaliES1 cds-NP_013100.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000083.1:17861-20134:- gene-YLL001W_JAY291 rna-NM_001181821.1_JAY291 cds-NP_013100.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:143369-145642:+ gene-YLL001W_MUCL30387 rna-NM_001181821.1_MUCL30387 cds-NP_013100.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:147867-150140:+ gene-YLL001W_MUCL30388 rna-NM_001181821.1_MUCL30388 cds-NP_013100.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:143717-145990:+ gene-YLL001W_MUCL39482 rna-NM_001181821.1_MUCL39482 cds-NP_013100.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:143385-145658:+ gene-YLL001W_MUCL42920 rna-NM_001181821.1_MUCL42920 cds-NP_013100.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:147864-150137:+ gene-YLL001W_NCIM3186 rna-NM_001181821.1_NCIM3186 cds-NP_013100.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:135320-137593:+ gene-YLL001W_NCYC1407 rna-NM_001181821.1_NCYC1407 cds-NP_013100.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:141668-143941:+ gene-YLL001W_PE2H3 rna-NM_001181821.1_PE2H3 cds-NP_013100.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:141409-143682:+ gene-YLL001W_PE2H4 rna-NM_001181821.1_PE2H4 cds-NP_013100.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:147890-150163:+ gene-YLL001W_S288C rna-NM_001181821.1_S288C cds-NP_013100.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000062.1:50851-53124:+ gene-YLL001W_SA1 rna-NM_001181821.1_SA1 cds-NP_013100.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:135742-138015:+ gene-YLL001W_ThermosaccDry rna-NM_001181821.1_ThermosaccDry cds-NP_013100.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:149342-151615:+ gene-YLL001W_VR1 rna-NM_001181821.1_VR1 cds-NP_013100.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:135070-137343:+ gene-YLL001W_ZTW1 rna-NM_001181821.1_ZTW1 cds-NP_013100.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:143450-145723:+ gene-YLL001W_Sparadoxus rna-NM_001181821.1_Sparadoxus cds-NP_013100.1_Sparadoxus 92.8 100.0 Verified 1 1 1 False True False False False

Additional files