DMC1 (YER179W)


Gene profile

Gene name: DMC1
Reference locus (S288C): YER179W
Gene biotype: protein_coding

Description: Meiotic recombination protein DMC1; Meiosis-specific recombinase required for double-strand break repair; also required for pairing between homologous chromosomes; required for the normal morphogenesis of synaptonemal complex; homolog of Rad51p and the bacterial RecA protein; binds ssDNA and dsDNA, forms helical filaments; stimulated by Rdh54p; Belongs to the RecA family. DMC1 subfamily

Top 10 interactors (score): SPO11 (0.998); RAD51 (0.993); RAD54 (0.991); HOP2 (0.987); RDH54 (0.984); PCH2 (0.982); RAD57 (0.98); MUS81 (0.974); HOP1 (0.974); MND1 (0.973); MSH4 (0.972); MEK1 (0.971); MLH1 (0.959); RAD52 (0.928); MSH5 (0.922); NDT80 (0.921); MEC1 (0.919); SGS1 (0.919); RFA1 (0.914); SAE3 (0.898)

Homologues (species, bitscore): DMC1 (Homo sapiens, 369.0); Dmc1 (Mus musculus, 372.1); dmc1 (Danio rerio, 370.9); rad51 (Xenopus tropicalis, 317.4); spn-A (Drosophila melanogaster, 303.1); rad-51 (Caenorhabditis elegans, 312.4); DMC1 (Arabidopsis thaliana, 349.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:529935-531031:+ gene-YER179W_AKU4011 rna-NM_001179069.1_AKU4011 cds-NP_011106.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000176.1:2339-3435:- gene-YER179W_BG1 rna-NM_001179069.1_BG1 cds-NP_011106.1_BG1 99.5 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:542681-543777:+ gene-YER179W_Bruggeman rna-NM_001179069.1_Bruggeman cds-NP_011106.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:529269-530365:+ gene-YER179W_CAT1 rna-NM_001179069.1_CAT1 cds-NP_011106.1_CAT1 99.2 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:529739-530835:+ gene-YER179W_CBS1585 rna-NM_001179069.1_CBS1585 cds-NP_011106.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:539630-540726:+ gene-YER179W_CBS436 rna-NM_001179069.1_CBS436 cds-NP_011106.1_CBS436 99.3 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:527716-528812:+ gene-YER179W_CBS6412 rna-NM_001179069.1_CBS6412 cds-NP_011106.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:536285-537381:+ gene-YER179W_CBS6413 rna-NM_001179069.1_CBS6413 cds-NP_011106.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:546186-547282:+ gene-YER179W_CENPK1137D rna-NM_001179069.1_CENPK1137D cds-NP_011106.1_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:535902-536998:+ gene-YER179W_EthanolRed rna-NM_001179069.1_EthanolRed cds-NP_011106.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:536838-537934:+ gene-YER179W_FaliES1 rna-NM_001179069.1_FaliES1 cds-NP_011106.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000169.1:1964-3059:- gene-YER179W_JAY291 rna-NM_001179069.1_JAY291 cds-NP_011106.1_JAY291 99.2 99.9 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:529991-531087:+ gene-YER179W_MUCL30387 rna-NM_001179069.1_MUCL30387 cds-NP_011106.1_MUCL30387 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:532904-534000:+ gene-YER179W_MUCL30388 rna-NM_001179069.1_MUCL30388 cds-NP_011106.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:525697-526793:+ gene-YER179W_MUCL39482 rna-NM_001179069.1_MUCL39482 cds-NP_011106.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:540223-541319:+ gene-YER179W_MUCL42920 rna-NM_001179069.1_MUCL42920 cds-NP_011106.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:548420-549516:+ gene-YER179W_NCIM3186 rna-NM_001179069.1_NCIM3186 cds-NP_011106.1_NCIM3186 97.0 100.0 Verified 1 1 0 False False True False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:535153-536249:+ gene-YER179W_NCYC1407 rna-NM_001179069.1_NCYC1407 cds-NP_011106.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:551093-552189:+ gene-YER179W_PE2H3 rna-NM_001179069.1_PE2H3 cds-NP_011106.1_PE2H3 99.3 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:541026-542122:+ gene-YER179W_PE2H4 rna-NM_001179069.1_PE2H4 cds-NP_011106.1_PE2H4 99.3 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:548421-549517:+ gene-YER179W_S288C rna-NM_001179069.1_S288C cds-NP_011106.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000030.1:100576-101672:+ gene-YER179W_SA1 rna-NM_001179069.1_SA1 cds-NP_011106.1_SA1 99.4 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:537638-538734:+ gene-YER179W_ThermosaccDry rna-NM_001179069.1_ThermosaccDry cds-NP_011106.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:530929-532025:+ gene-YER179W_VR1 rna-NM_001179069.1_VR1 cds-NP_011106.1_VR1 99.3 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000011.1:50491-51587:+ gene-YER179W_ZTW1 rna-NM_001179069.1_ZTW1 cds-NP_011106.1_ZTW1 99.3 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:538947-540042:+ gene-YER179W_Sparadoxus rna-NM_001179069.1_Sparadoxus cds-NP_011106.1_Sparadoxus 91.9 100.0 Verified 1 1 1 False True False False False

Additional files