Gene name: DMA2
Reference locus (S288C): YNL116W
Gene biotype: protein_coding
Description: Ubiquitin-protein ligase (E3); controls septin dynamics and spindle position checkpoint (SPOC) with ligase Dma1p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ortholog of human RNF8, similar to human Chfr; contains FHA and RING finger domains; DMA2 has a paralog, DMA1, that arose from the whole genome duplication
Top 10 interactors (score): CDC123 (0.928); UBC13 (0.914); DMA1 (0.893); BUB2 (0.853); CDC5 (0.826); UFD4 (0.79); RAD9 (0.781); TEL1 (0.776); RTT107 (0.742); FAR8 (0.729); FAR11 (0.719); SWE1 (0.713); SHS1 (0.689); MAG2 (0.673); YBR062C (0.669); UBC4 (0.646); UBC5 (0.644); TEM1 (0.626); KIN4 (0.619); CLA4 (0.613)
Homologues (species, bitscore): SLMAP (Homo sapiens, 60.8); Slmap (Mus musculus, 57.8); slmapa (Danio rerio, 60.5); slmap (Xenopus tropicalis, 60.8); Slmap (Drosophila melanogaster, 53.9); M4.1 (Caenorhabditis elegans, 58.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:402023-403591:+ | gene-YNL116W_AKU4011 | rna-NM_001182954.3_AKU4011 | cds-NP_014283.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:306017-307585:+ | gene-YNL116W_BG1 | rna-NM_001182954.3_BG1 | cds-NP_014283.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:412489-414057:+ | gene-YNL116W_Bruggeman | rna-NM_001182954.3_Bruggeman | cds-NP_014283.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:455787-457355:+ | gene-YNL116W_CAT1 | rna-NM_001182954.3_CAT1 | cds-NP_014283.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:402643-404211:+ | gene-YNL116W_CBS1585 | rna-NM_001182954.3_CBS1585 | cds-NP_014283.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:471052-472620:+ | gene-YNL116W_CBS436 | rna-NM_001182954.3_CBS436 | cds-NP_014283.3_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:398096-399664:+ | gene-YNL116W_CBS6412 | rna-NM_001182954.3_CBS6412 | cds-NP_014283.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:399061-400629:+ | gene-YNL116W_CBS6413 | rna-NM_001182954.3_CBS6413 | cds-NP_014283.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:402191-403759:+ | gene-YNL116W_CENPK1137D | rna-NM_001182954.3_CENPK1137D | cds-NP_014283.3_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:399013-400581:+ | gene-YNL116W_EthanolRed | rna-NM_001182954.3_EthanolRed | cds-NP_014283.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:394915-396483:+ | gene-YNL116W_FaliES1 | rna-NM_001182954.3_FaliES1 | cds-NP_014283.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000021.1:51293-52861:+ | gene-YNL116W_JAY291 | rna-NM_001182954.3_JAY291 | cds-NP_014283.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:408908-410476:+ | gene-YNL116W_MUCL30387 | rna-NM_001182954.3_MUCL30387 | cds-NP_014283.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:444087-445655:+ | gene-YNL116W_MUCL30388 | rna-NM_001182954.3_MUCL30388 | cds-NP_014283.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:399922-401490:+ | gene-YNL116W_MUCL39482 | rna-NM_001182954.3_MUCL39482 | cds-NP_014283.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:403162-404730:+ | gene-YNL116W_MUCL42920 | rna-NM_001182954.3_MUCL42920 | cds-NP_014283.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:408310-409878:+ | gene-YNL116W_NCIM3186 | rna-NM_001182954.3_NCIM3186 | cds-NP_014283.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:402054-403622:+ | gene-YNL116W_NCYC1407 | rna-NM_001182954.3_NCYC1407 | cds-NP_014283.3_NCYC1407 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:401043-402611:+ | gene-YNL116W_PE2H3 | rna-NM_001182954.3_PE2H3 | cds-NP_014283.3_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:400449-402017:+ | gene-YNL116W_PE2H4 | rna-NM_001182954.3_PE2H4 | cds-NP_014283.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:408341-409909:+ | gene-YNL116W_S288C | rna-NM_001182954.3_S288C | cds-NP_014283.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:3620-5188:- | gene-YNL116W_SA1 | rna-NM_001182954.3_SA1 | cds-NP_014283.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:395769-397337:+ | gene-YNL116W_ThermosaccDry | rna-NM_001182954.3_ThermosaccDry | cds-NP_014283.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:414432-416000:+ | gene-YNL116W_VR1 | rna-NM_001182954.3_VR1 | cds-NP_014283.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:305602-307170:+ | gene-YNL116W_ZTW1 | rna-NM_001182954.3_ZTW1 | cds-NP_014283.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:406614-408215:+ | gene-YNL116W_Sparadoxus | rna-NM_001182954.3_Sparadoxus | cds-NP_014283.3_Sparadoxus | 88.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |