Gene name: DLD1
Reference locus (S288C): YDL174C
Gene biotype: protein_coding
Description: Major mitochondrial D-lactate dehydrogenase; oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane
Top 10 interactors (score): CYB2 (0.994); COQ2 (0.932); NDE1 (0.924); PDB1 (0.918); NDE2 (0.917); CDC19 (0.917); COX5A (0.917); PYC1 (0.917); GLO4 (0.915); ATP2 (0.913); GLO2 (0.911); PYC2 (0.909); PYK2 (0.907); MAE1 (0.903); PDA1 (0.902); OLI1 (0.901); SNO4 (0.9); HSP33 (0.9); HSP31 (0.9); COX4 (0.9)
Homologues (species, bitscore): LDHD (Homo sapiens, 305.4); Ldhd (Mus musculus, 319.7); ldhd (Danio rerio, 332.8); LDHD (Xenopus tropicalis, 327.0); CG3835 (Drosophila melanogaster, 141.0); F32D8.12 (Caenorhabditis elegans, 339.7); AT5G06580 (Arabidopsis thaliana, 352.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:130252-132015:- | gene-YDL174C_AKU4011 | rna-NM_001180234.1_AKU4011 | cds-NP_010107.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:417697-419460:+ | gene-YDL174C_BG1 | rna-NM_001180234.1_BG1 | cds-NP_010107.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:146308-148071:- | gene-YDL174C_Bruggeman | rna-NM_001180234.1_Bruggeman | cds-NP_010107.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:144633-146396:- | gene-YDL174C_CAT1 | rna-NM_001180234.1_CAT1 | cds-NP_010107.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:128290-130053:- | gene-YDL174C_CBS1585 | rna-NM_001180234.1_CBS1585 | cds-NP_010107.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:145248-147011:- | gene-YDL174C_CBS436 | rna-NM_001180234.1_CBS436 | cds-NP_010107.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:127853-129616:- | gene-YDL174C_CBS6412 | rna-NM_001180234.1_CBS6412 | cds-NP_010107.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:146664-148427:- | gene-YDL174C_CBS6413 | rna-NM_001180234.1_CBS6413 | cds-NP_010107.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:144499-146262:- | gene-YDL174C_CENPK1137D | rna-NM_001180234.1_CENPK1137D | cds-NP_010107.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:141672-143435:- | gene-YDL174C_EthanolRed | rna-NM_001180234.1_EthanolRed | cds-NP_010107.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:146998-148761:- | gene-YDL174C_FaliES1 | rna-NM_001180234.1_FaliES1 | cds-NP_010107.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:70751-72514:+ | gene-YDL174C_JAY291 | rna-NM_001180234.1_JAY291 | cds-NP_010107.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:144609-146372:- | gene-YDL174C_MUCL30387 | rna-NM_001180234.1_MUCL30387 | cds-NP_010107.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:136259-138022:- | gene-YDL174C_MUCL30388 | rna-NM_001180234.1_MUCL30388 | cds-NP_010107.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:129432-131195:- | gene-YDL174C_MUCL39482 | rna-NM_001180234.1_MUCL39482 | cds-NP_010107.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000307.1:38174-39937:+ | gene-YDL174C_MUCL42920 | rna-NM_001180234.1_MUCL42920 | cds-NP_010107.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:145749-147512:- | gene-YDL174C_NCIM3186 | rna-NM_001180234.1_NCIM3186 | cds-NP_010107.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:129321-131084:- | gene-YDL174C_NCYC1407 | rna-NM_001180234.1_NCYC1407 | cds-NP_010107.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:136629-138392:- | gene-YDL174C_PE2H3 | rna-NM_001180234.1_PE2H3 | cds-NP_010107.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:136633-138396:- | gene-YDL174C_PE2H4 | rna-NM_001180234.1_PE2H4 | cds-NP_010107.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:145826-147589:- | gene-YDL174C_S288C | rna-NM_001180234.1_S288C | cds-NP_010107.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:11406-13169:- | gene-YDL174C_SA1 | rna-NM_001180234.1_SA1 | cds-NP_010107.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:146758-148521:- | gene-YDL174C_ThermosaccDry | rna-NM_001180234.1_ThermosaccDry | cds-NP_010107.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:147400-149163:- | gene-YDL174C_VR1 | rna-NM_001180234.1_VR1 | cds-NP_010107.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:144933-146696:- | gene-YDL174C_ZTW1 | rna-NM_001180234.1_ZTW1 | cds-NP_010107.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:147129-148892:- | gene-YDL174C_Sparadoxus | rna-NM_001180234.1_Sparadoxus | cds-NP_010107.1_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |