Gene name: DIN7
Reference locus (S288C): YDR263C
Gene biotype: protein_coding
Description: DNA damage-inducible protein DIN7; Mitochondrial nuclease functioning in DNA repair and replication; modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination; DIN7 has a paralog, EXO1, that arose from the whole genome duplication; Belongs to the XPG/RAD2 endonuclease family
Top 10 interactors (score): SGS1 (0.996); MSH2 (0.992); RAD51 (0.95); MLH1 (0.937); CDC45 (0.929); DNA2 (0.922); RNR2 (0.91); MCM2 (0.908); DUN1 (0.904); MCM5 (0.9); RAD54 (0.897); ORC1 (0.896); CDC6 (0.89); YKU80 (0.885); MRE11 (0.882); MPS1 (0.881); CHK1 (0.862); MEC1 (0.82); MHR1 (0.818); CDC9 (0.817)
Homologues (species, bitscore): EXO1 (Homo sapiens, 194.9); Exo1 (Mus musculus, 191.4); exo1 (Danio rerio, 199.5); exo1 (Xenopus tropicalis, 123.2); tos (Drosophila melanogaster, 162.9); exo-1 (Caenorhabditis elegans, 119.8); AT1G29630 (Arabidopsis thaliana, 178.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:946531-947823:- | gene-YDR263C_AKU4011 | rna-NM_001180571.3_AKU4011 | cds-NP_010549.3_AKU4011 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:184501-185793:+ | gene-YDR263C_BG1 | rna-NM_001180571.3_BG1 | cds-NP_010549.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:972708-974000:- | gene-YDR263C_Bruggeman | rna-NM_001180571.3_Bruggeman | cds-NP_010549.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:960546-961838:- | gene-YDR263C_CAT1 | rna-NM_001180571.3_CAT1 | cds-NP_010549.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:940976-942268:- | gene-YDR263C_CBS1585 | rna-NM_001180571.3_CBS1585 | cds-NP_010549.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:959014-960306:- | gene-YDR263C_CBS436 | rna-NM_001180571.3_CBS436 | cds-NP_010549.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:937659-938951:- | gene-YDR263C_CBS6412 | rna-NM_001180571.3_CBS6412 | cds-NP_010549.3_CBS6412 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:958895-960187:- | gene-YDR263C_CBS6413 | rna-NM_001180571.3_CBS6413 | cds-NP_010549.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:992885-994177:- | gene-YDR263C_CENPK1137D | rna-NM_001180571.3_CENPK1137D | cds-NP_010549.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:945076-946368:- | gene-YDR263C_EthanolRed | rna-NM_001180571.3_EthanolRed | cds-NP_010549.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:953278-954570:- | gene-YDR263C_FaliES1 | rna-NM_001180571.3_FaliES1 | cds-NP_010549.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000176.1:1540-2832:- | gene-YDR263C_JAY291 | rna-NM_001180571.3_JAY291 | cds-NP_010549.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:958340-959632:- | gene-YDR263C_MUCL30387 | rna-NM_001180571.3_MUCL30387 | cds-NP_010549.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:946053-947345:- | gene-YDR263C_MUCL30388 | rna-NM_001180571.3_MUCL30388 | cds-NP_010549.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:932782-934074:- | gene-YDR263C_MUCL39482 | rna-NM_001180571.3_MUCL39482 | cds-NP_010549.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:872778-874070:- | gene-YDR263C_MUCL42920 | rna-NM_001180571.3_MUCL42920 | cds-NP_010549.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:994165-995457:- | gene-YDR263C_NCIM3186 | rna-NM_001180571.3_NCIM3186 | cds-NP_010549.3_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:946072-947364:- | gene-YDR263C_NCYC1407 | rna-NM_001180571.3_NCYC1407 | cds-NP_010549.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:956707-957999:- | gene-YDR263C_PE2H3 | rna-NM_001180571.3_PE2H3 | cds-NP_010549.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:961984-963276:- | gene-YDR263C_PE2H4 | rna-NM_001180571.3_PE2H4 | cds-NP_010549.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:994242-995534:- | gene-YDR263C_S288C | rna-NM_001180571.3_S288C | cds-NP_010549.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000102.1:1864-3156:- | gene-YDR263C_SA1 | rna-NM_001180571.3_SA1 | cds-NP_010549.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:957563-958855:- | gene-YDR263C_ThermosaccDry | rna-NM_001180571.3_ThermosaccDry | cds-NP_010549.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:973163-974455:- | gene-YDR263C_VR1 | rna-NM_001180571.3_VR1 | cds-NP_010549.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:1692-2984:- | gene-YDR263C_ZTW1 | rna-NM_001180571.3_ZTW1 | cds-NP_010549.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:954012-955304:- | gene-YDR263C_Sparadoxus | rna-NM_001180571.3_Sparadoxus | cds-NP_010549.3_Sparadoxus | 87.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |