DIM1 (YPL266W)


Gene profile

Gene name: DIM1
Reference locus (S288C): YPL266W
Gene biotype: protein_coding

Description: Essential 18S rRNA dimethylase (dimethyladenosine transferase); responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing; human homolog DIMT1 complements yeast dim1 mutant

Top 10 interactors (score): SOF1 (0.999); UTP4 (0.999); RRP5 (0.999); BMS1 (0.999); ENP1 (0.999); PWP2 (0.999); NOP56 (0.999); NAN1 (0.999); UTP15 (0.999); DIP2 (0.999); RRP9 (0.999); PNO1 (0.999); IMP3 (0.999); YTM1 (0.999); UTP13 (0.999); RIO2 (0.999); NOP58 (0.999); IMP4 (0.999); TSR1 (0.999); NOP1 (0.999)

Homologues (species, bitscore): DIMT1 (Homo sapiens, 372.1); Dimt1 (Mus musculus, 370.9); dimt1l (Danio rerio, 368.2); dimt1 (Xenopus tropicalis, 371.3); CG11837 (Drosophila melanogaster, 366.7); E02H1.1 (Caenorhabditis elegans, 307.8); DIM1A (Arabidopsis thaliana, 334.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:23427-24383:+ gene-YPL266W_AKU4011 rna-NM_001184080.1_AKU4011 cds-NP_015057.1_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000185.1:16405-17361:- gene-YPL266W_BG1 rna-NM_001184080.1_BG1 cds-NP_015057.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:40663-41619:+ gene-YPL266W_Bruggeman rna-NM_001184080.1_Bruggeman cds-NP_015057.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:38630-39586:+ gene-YPL266W_CAT1 rna-NM_001184080.1_CAT1 cds-NP_015057.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:27135-28091:+ gene-YPL266W_CBS1585 rna-NM_001184080.1_CBS1585 cds-NP_015057.1_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:35525-36481:+ gene-YPL266W_CBS436 rna-NM_001184080.1_CBS436 cds-NP_015057.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:32039-32995:+ gene-YPL266W_CBS6412 rna-NM_001184080.1_CBS6412 cds-NP_015057.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:23287-24243:+ gene-YPL266W_CBS6413 rna-NM_001184080.1_CBS6413 cds-NP_015057.1_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:39069-40025:+ gene-YPL266W_CENPK1137D rna-NM_001184080.1_CENPK1137D cds-NP_015057.1_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:22466-23422:+ gene-YPL266W_EthanolRed rna-NM_001184080.1_EthanolRed cds-NP_015057.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:22814-23770:+ gene-YPL266W_FaliES1 rna-NM_001184080.1_FaliES1 cds-NP_015057.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000190.1:16318-17274:- gene-YPL266W_JAY291 rna-NM_001184080.1_JAY291 cds-NP_015057.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:39937-40893:+ gene-YPL266W_MUCL30387 rna-NM_001184080.1_MUCL30387 cds-NP_015057.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:38126-39082:+ gene-YPL266W_MUCL30388 rna-NM_001184080.1_MUCL30388 cds-NP_015057.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:20265-21221:+ gene-YPL266W_MUCL39482 rna-NM_001184080.1_MUCL39482 cds-NP_015057.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:32422-33378:+ gene-YPL266W_MUCL42920 rna-NM_001184080.1_MUCL42920 cds-NP_015057.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:39104-40060:+ gene-YPL266W_NCIM3186 rna-NM_001184080.1_NCIM3186 cds-NP_015057.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:26711-27667:+ gene-YPL266W_NCYC1407 rna-NM_001184080.1_NCYC1407 cds-NP_015057.1_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:30360-31316:+ gene-YPL266W_PE2H3 rna-NM_001184080.1_PE2H3 cds-NP_015057.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:30337-31293:+ gene-YPL266W_PE2H4 rna-NM_001184080.1_PE2H4 cds-NP_015057.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:39121-40077:+ gene-YPL266W_S288C rna-NM_001184080.1_S288C cds-NP_015057.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000104.1:16446-17402:- gene-YPL266W_SA1 rna-NM_001184080.1_SA1 cds-NP_015057.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:22815-23771:+ gene-YPL266W_ThermosaccDry rna-NM_001184080.1_ThermosaccDry cds-NP_015057.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:269215-270171:+ gene-YPL266W_VR1 rna-NM_001184080.1_VR1 cds-NP_015057.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:28937-29893:+ gene-YPL266W_ZTW1 rna-NM_001184080.1_ZTW1 cds-NP_015057.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:30801-31757:+ gene-YPL266W_Sparadoxus rna-NM_001184080.1_Sparadoxus cds-NP_015057.1_Sparadoxus 92.4 100.0 Verified 1 1 1 False True False False False

Additional files