Gene name: DIG2
Reference locus (S288C): YDR480W
Gene biotype: protein_coding
Description: Down-regulator of invasive growth 2; MAP kinase-responsive inhibitor of the Ste12p transcription factor; involved in the regulation of mating-specific genes and the invasive growth pathway; related regulators Dig1p and Dig2p bind to Ste12p; DIG2 has a paralog, DIG1, that arose from the whole genome duplication
Top 10 interactors (score): STE12 (0.999); DIG1 (0.999); FUS3 (0.998); KSS1 (0.997); TEC1 (0.872); STE7 (0.85); FUS1 (0.818); STE11 (0.813); STE5 (0.813); STE50 (0.757); STE20 (0.749); FAR1 (0.748); STE4 (0.747); STE18 (0.746); GPA1 (0.718); STE2 (0.712); SST2 (0.699); PRM1 (0.694); AGA1 (0.687); MRX12 (0.659)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1357323-1358294:+ | gene-YDR480W_AKU4011 | rna-NM_001180788.1_AKU4011 | cds-NP_010768.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:232428-233399:+ | gene-YDR480W_BG1 | rna-NM_001180788.1_BG1 | cds-NP_010768.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1388730-1389701:+ | gene-YDR480W_Bruggeman | rna-NM_001180788.1_Bruggeman | cds-NP_010768.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1365878-1366849:+ | gene-YDR480W_CAT1 | rna-NM_001180788.1_CAT1 | cds-NP_010768.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1351622-1352593:+ | gene-YDR480W_CBS1585 | rna-NM_001180788.1_CBS1585 | cds-NP_010768.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1370980-1371951:+ | gene-YDR480W_CBS436 | rna-NM_001180788.1_CBS436 | cds-NP_010768.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1347246-1348217:+ | gene-YDR480W_CBS6412 | rna-NM_001180788.1_CBS6412 | cds-NP_010768.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1370257-1371228:+ | gene-YDR480W_CBS6413 | rna-NM_001180788.1_CBS6413 | cds-NP_010768.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1416095-1417066:+ | gene-YDR480W_CENPK1137D | rna-NM_001180788.1_CENPK1137D | cds-NP_010768.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1360664-1361635:+ | gene-YDR480W_EthanolRed | rna-NM_001180788.1_EthanolRed | cds-NP_010768.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1364217-1365188:+ | gene-YDR480W_FaliES1 | rna-NM_001180788.1_FaliES1 | cds-NP_010768.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:62469-63440:+ | gene-YDR480W_JAY291 | rna-NM_001180788.1_JAY291 | cds-NP_010768.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1371221-1372192:+ | gene-YDR480W_MUCL30387 | rna-NM_001180788.1_MUCL30387 | cds-NP_010768.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1353244-1354215:+ | gene-YDR480W_MUCL30388 | rna-NM_001180788.1_MUCL30388 | cds-NP_010768.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1343107-1344078:+ | gene-YDR480W_MUCL39482 | rna-NM_001180788.1_MUCL39482 | cds-NP_010768.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1285896-1286867:+ | gene-YDR480W_MUCL42920 | rna-NM_001180788.1_MUCL42920 | cds-NP_010768.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1417322-1418293:+ | gene-YDR480W_NCIM3186 | rna-NM_001180788.1_NCIM3186 | cds-NP_010768.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1356876-1357847:+ | gene-YDR480W_NCYC1407 | rna-NM_001180788.1_NCYC1407 | cds-NP_010768.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1367721-1368692:+ | gene-YDR480W_PE2H3 | rna-NM_001180788.1_PE2H3 | cds-NP_010768.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1373295-1374266:+ | gene-YDR480W_PE2H4 | rna-NM_001180788.1_PE2H4 | cds-NP_010768.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1417399-1418370:+ | gene-YDR480W_S288C | rna-NM_001180788.1_S288C | cds-NP_010768.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:198788-199759:- | gene-YDR480W_SA1 | rna-NM_001180788.1_SA1 | cds-NP_010768.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1368439-1369410:+ | gene-YDR480W_ThermosaccDry | rna-NM_001180788.1_ThermosaccDry | cds-NP_010768.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1384164-1385135:+ | gene-YDR480W_VR1 | rna-NM_001180788.1_VR1 | cds-NP_010768.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:411105-412076:+ | gene-YDR480W_ZTW1 | rna-NM_001180788.1_ZTW1 | cds-NP_010768.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1371206-1372177:+ | gene-YDR480W_Sparadoxus | rna-NM_001180788.1_Sparadoxus | cds-NP_010768.1_Sparadoxus | 87.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |