Gene name: DIG1
Reference locus (S288C): YPL049C
Gene biotype: protein_coding
Description: Down-regulator of invasive growth 1; MAP kinase-responsive inhibitor of the Ste12p transcription factor; involved in the regulation of mating-specific genes and the invasive growth pathway; related regulators Dig1p and Dig2p bind to Ste12p; DIG1 has a paralog, DIG2, that arose from the whole genome duplication
Top 10 interactors (score): STE12 (0.999); DIG2 (0.999); KSS1 (0.998); TEC1 (0.997); FUS3 (0.997); STE7 (0.865); MCM1 (0.858); FUS1 (0.828); STE11 (0.813); STE5 (0.813); SWI6 (0.792); SWI4 (0.78); FAR1 (0.76); STE20 (0.75); STE4 (0.748); GPA1 (0.746); HMLALPHA1 (0.732); STE50 (0.724); STE2 (0.718); STE18 (0.712)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:433976-435340:- | gene-YPL049C_AKU4011 | rna-NM_001183863.1_AKU4011 | cds-NP_015276.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:462106-463464:+ | gene-YPL049C_BG1 | rna-NM_001183863.1_BG1 | cds-NP_015276.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:510922-512280:- | gene-YPL049C_Bruggeman | rna-NM_001183863.1_Bruggeman | cds-NP_015276.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:550608-551966:- | gene-YPL049C_CAT1 | rna-NM_001183863.1_CAT1 | cds-NP_015276.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:438044-439408:- | gene-YPL049C_CBS1585 | rna-NM_001183863.1_CBS1585 | cds-NP_015276.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:452167-453525:- | gene-YPL049C_CBS436 | rna-NM_001183863.1_CBS436 | cds-NP_015276.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:442234-443598:- | gene-YPL049C_CBS6412 | rna-NM_001183863.1_CBS6412 | cds-NP_015276.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:434595-435959:- | gene-YPL049C_CBS6413 | rna-NM_001183863.1_CBS6413 | cds-NP_015276.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:462458-463816:- | gene-YPL049C_CENPK1137D | rna-NM_001183863.1_CENPK1137D | cds-NP_015276.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:432331-433695:- | gene-YPL049C_EthanolRed | rna-NM_001183863.1_EthanolRed | cds-NP_015276.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:440161-441525:- | gene-YPL049C_FaliES1 | rna-NM_001183863.1_FaliES1 | cds-NP_015276.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000283.1:48758-50116:- | gene-YPL049C_JAY291 | rna-NM_001183863.1_JAY291 | cds-NP_015276.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:451856-453214:- | gene-YPL049C_MUCL30387 | rna-NM_001183863.1_MUCL30387 | cds-NP_015276.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:450997-452355:- | gene-YPL049C_MUCL30388 | rna-NM_001183863.1_MUCL30388 | cds-NP_015276.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:431360-432724:- | gene-YPL049C_MUCL39482 | rna-NM_001183863.1_MUCL39482 | cds-NP_015276.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:489960-491318:- | gene-YPL049C_MUCL42920 | rna-NM_001183863.1_MUCL42920 | cds-NP_015276.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:462464-463822:- | gene-YPL049C_NCIM3186 | rna-NM_001183863.1_NCIM3186 | cds-NP_015276.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:438638-440002:- | gene-YPL049C_NCYC1407 | rna-NM_001183863.1_NCYC1407 | cds-NP_015276.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:445252-446610:- | gene-YPL049C_PE2H3 | rna-NM_001183863.1_PE2H3 | cds-NP_015276.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:444867-446225:- | gene-YPL049C_PE2H4 | rna-NM_001183863.1_PE2H4 | cds-NP_015276.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:462481-463839:- | gene-YPL049C_S288C | rna-NM_001183863.1_S288C | cds-NP_015276.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000077.1:309-1667:- | gene-YPL049C_SA1 | rna-NM_001183863.1_SA1 | cds-NP_015276.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:439960-441324:- | gene-YPL049C_ThermosaccDry | rna-NM_001183863.1_ThermosaccDry | cds-NP_015276.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:454783-456141:- | gene-YPL049C_VR1 | rna-NM_001183863.1_VR1 | cds-NP_015276.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:439266-440626:- | gene-YPL049C_ZTW1 | rna-NM_001183863.1_ZTW1 | cds-NP_015276.1_ZTW1 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:439876-441243:- | gene-YPL049C_Sparadoxus | rna-NM_001183863.1_Sparadoxus | cds-NP_015276.1_Sparadoxus | 86.7 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |