Gene name: DIF1
Reference locus (S288C): YLR437C
Gene biotype: protein_coding
Description: Damage-regulated import facilitator 1; Protein that regulates nuclear localization of Rnr2p and Rnr4p; phosphorylated by Dun1p in response to DNA damage and degraded; N-terminal half shows similarity to S. pombe Spd1 protein; DIF1 has a paralog, SML1, that arose from the whole genome duplication
Top 10 interactors (score): WTM1 (0.917); SML1 (0.911); DUN1 (0.905); RNR2 (0.862); MEC1 (0.849); RNR4 (0.82); HUG1 (0.766); RNR1 (0.754); RAD53 (0.749); RNR3 (0.699); RFX1 (0.698); YIR020C (0.697); YCR022C (0.697); YGR176W (0.618); MAK32 (0.614); IXR1 (0.581); YCR051W (0.567); ECM30 (0.526); MUB1 (0.499); YCR007C (0.499)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:949877-950278:- | gene-YLR437C_AKU4011 | rna-NM_001182325.3_AKU4011 | cds-NP_013541.3_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:182333-182740:- | gene-YLR437C_BG1 | rna-NM_001182325.3_BG1 | cds-NP_013541.3_BG1 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:988184-988582:- | gene-YLR437C_Bruggeman | rna-NM_001182325.3_Bruggeman | cds-NP_013541.3_Bruggeman | 98.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:984198-984593:- | gene-YLR437C_CAT1 | rna-NM_001182325.3_CAT1 | cds-NP_013541.3_CAT1 | 98.5 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:985474-985869:- | gene-YLR437C_CBS1585 | rna-NM_001182325.3_CBS1585 | cds-NP_013541.3_CBS1585 | 98.0 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:974817-975218:- | gene-YLR437C_CBS436 | rna-NM_001182325.3_CBS436 | cds-NP_013541.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:1021514-1021909:- | gene-YLR437C_CBS6412 | rna-NM_001182325.3_CBS6412 | cds-NP_013541.3_CBS6412 | 98.0 | 98.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:986259-986657:- | gene-YLR437C_CBS6413 | rna-NM_001182325.3_CBS6413 | cds-NP_013541.3_CBS6413 | 99.2 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:996235-996636:- | gene-YLR437C_CENPK1137D | rna-NM_001182325.3_CENPK1137D | cds-NP_013541.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:942905-943300:- | gene-YLR437C_EthanolRed | rna-NM_001182325.3_EthanolRed | cds-NP_013541.3_EthanolRed | 97.7 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:978176-978571:- | gene-YLR437C_FaliES1 | rna-NM_001182325.3_FaliES1 | cds-NP_013541.3_FaliES1 | 97.7 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000194.1:40115-40513:+ | gene-YLR437C_JAY291 | rna-NM_001182325.3_JAY291 | cds-NP_013541.3_JAY291 | 99.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:987045-987443:- | gene-YLR437C_MUCL30387 | rna-NM_001182325.3_MUCL30387 | cds-NP_013541.3_MUCL30387 | 98.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:994402-994800:- | gene-YLR437C_MUCL30388 | rna-NM_001182325.3_MUCL30388 | cds-NP_013541.3_MUCL30388 | 98.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:986694-987089:- | gene-YLR437C_MUCL39482 | rna-NM_001182325.3_MUCL39482 | cds-NP_013541.3_MUCL39482 | 98.0 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:987193-987591:- | gene-YLR437C_MUCL42920 | rna-NM_001182325.3_MUCL42920 | cds-NP_013541.3_MUCL42920 | 98.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:1011596-1011997:- | gene-YLR437C_NCIM3186 | rna-NM_001182325.3_NCIM3186 | cds-NP_013541.3_NCIM3186 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:996122-996523:- | gene-YLR437C_NCYC1407 | rna-NM_001182325.3_NCYC1407 | cds-NP_013541.3_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:982573-982971:- | gene-YLR437C_PE2H3 | rna-NM_001182325.3_PE2H3 | cds-NP_013541.3_PE2H3 | 99.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:982317-982715:- | gene-YLR437C_PE2H4 | rna-NM_001182325.3_PE2H4 | cds-NP_013541.3_PE2H4 | 99.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:1011622-1012023:- | gene-YLR437C_S288C | rna-NM_001182325.3_S288C | cds-NP_013541.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:47935-48336:+ | gene-YLR437C_SA1 | rna-NM_001182325.3_SA1 | cds-NP_013541.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:981255-981650:- | gene-YLR437C_ThermosaccDry | rna-NM_001182325.3_ThermosaccDry | cds-NP_013541.3_ThermosaccDry | 97.7 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:987678-988076:- | gene-YLR437C_VR1 | rna-NM_001182325.3_VR1 | cds-NP_013541.3_VR1 | 99.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:311527-311922:- | gene-YLR437C_ZTW1 | rna-NM_001182325.3_ZTW1 | cds-NP_013541.3_ZTW1 | 98.0 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:960657-961052:- | gene-YLR437C_Sparadoxus | rna-NM_001182325.3_Sparadoxus | cds-NP_013541.3_Sparadoxus | 93.7 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |