DIE2 (YGR227W)


Gene profile

Gene name: DIE2
Reference locus (S288C): YGR227W
Gene biotype: protein_coding

Description: Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase; located in the ER; functions in pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation; has a role in regulation of ITR1 and INO1; human homolog ALG10B can complement yeast die2 null mutant

Top 10 interactors (score): STT3 (0.999); ALG8 (0.999); OST3 (0.996); ALG6 (0.995); ALG9 (0.995); OST5 (0.995); ALG12 (0.994); OST6 (0.991); ALG5 (0.991); WBP1 (0.99); ALG3 (0.989); OST1 (0.988); SWP1 (0.986); ALG11 (0.974); ALG13 (0.96); OST2 (0.96); ITR1 (0.933); KEG1 (0.925); ALG7 (0.924); CWH41 (0.911)

Homologues (species, bitscore): ALG10B (Homo sapiens, 142.9); Alg10b (Mus musculus, 147.9); alg10 (Danio rerio, 150.2); alg10 (Xenopus tropicalis, 144.1); Alg10 (Drosophila melanogaster, 132.9); tag-179 (Caenorhabditis elegans, 115.5); ALG10 (Arabidopsis thaliana, 146.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:912725-914302:+ gene-YGR227W_AKU4011 rna-NM_001181356.2_AKU4011 cds-NP_011743.2_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:192947-194524:+ gene-YGR227W_BG1 rna-NM_001181356.2_BG1 cds-NP_011743.2_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:920429-922006:+ gene-YGR227W_Bruggeman rna-NM_001181356.2_Bruggeman cds-NP_011743.2_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:918677-920683:+ gene-YGR227W_CAT1 rna-NM_001181356.2_CAT1 cds-NP_011743.2_CAT1 78.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:915675-917252:+ gene-YGR227W_CBS1585 rna-NM_001181356.2_CBS1585 cds-NP_011743.2_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:919354-920931:+ gene-YGR227W_CBS436 rna-NM_001181356.2_CBS436 cds-NP_011743.2_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:906545-908122:+ gene-YGR227W_CBS6412 rna-NM_001181356.2_CBS6412 cds-NP_011743.2_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:912604-914181:+ gene-YGR227W_CBS6413 rna-NM_001181356.2_CBS6413 cds-NP_011743.2_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:947002-948579:+ gene-YGR227W_CENPK1137D rna-NM_001181356.2_CENPK1137D cds-NP_011743.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:901054-902631:+ gene-YGR227W_EthanolRed rna-NM_001181356.2_EthanolRed cds-NP_011743.2_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:905445-907022:+ gene-YGR227W_FaliES1 rna-NM_001181356.2_FaliES1 cds-NP_011743.2_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000076.1:123244-124821:- gene-YGR227W_JAY291 rna-NM_001181356.2_JAY291 cds-NP_011743.2_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:918344-919921:+ gene-YGR227W_MUCL30387 rna-NM_001181356.2_MUCL30387 cds-NP_011743.2_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:917600-919177:+ gene-YGR227W_MUCL30388 rna-NM_001181356.2_MUCL30388 cds-NP_011743.2_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:910752-912329:+ gene-YGR227W_MUCL39482 rna-NM_001181356.2_MUCL39482 cds-NP_011743.2_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:929304-930881:+ gene-YGR227W_MUCL42920 rna-NM_001181356.2_MUCL42920 cds-NP_011743.2_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:947420-948997:+ gene-YGR227W_NCIM3186 rna-NM_001181356.2_NCIM3186 cds-NP_011743.2_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:906404-907981:+ gene-YGR227W_NCYC1407 rna-NM_001181356.2_NCYC1407 cds-NP_011743.2_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:931344-932921:+ gene-YGR227W_PE2H3 rna-NM_001181356.2_PE2H3 cds-NP_011743.2_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:936450-938027:+ gene-YGR227W_PE2H4 rna-NM_001181356.2_PE2H4 cds-NP_011743.2_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:947420-948997:+ gene-YGR227W_S288C rna-NM_001181356.2_S288C cds-NP_011743.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000045.1:52765-54342:- gene-YGR227W_SA1 rna-NM_001181356.2_SA1 cds-NP_011743.2_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:925956-927533:+ gene-YGR227W_ThermosaccDry rna-NM_001181356.2_ThermosaccDry cds-NP_011743.2_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:1030771-1032348:+ gene-YGR227W_VR1 rna-NM_001181356.2_VR1 cds-NP_011743.2_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:227391-228968:+ gene-YGR227W_ZTW1 rna-NM_001181356.2_ZTW1 cds-NP_011743.2_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:918136-919713:+ gene-YGR227W_Sparadoxus rna-NM_001181356.2_Sparadoxus cds-NP_011743.2_Sparadoxus 92.0 99.9 Verified 1 1 1 False True False False False

Additional files