DID2 (YKR035W-A)


Gene profile

Gene name: DID2
Reference locus (S288C): YKR035W-A
Gene biotype: protein_coding

Description: Class E protein of the vacuolar protein-sorting (Vps) pathway; binds Vps4p and directs it to dissociate ESCRT-III complexes; forms a functional and physical complex with Ist1p; human ortholog may be altered in breast tumors

Top 10 interactors (score): VPS60 (0.999); VTA1 (0.999); DID4 (0.999); VPS4 (0.999); VPS24 (0.999); IST1 (0.999); SNF7 (0.999); VPS20 (0.994); VPS25 (0.982); VPS36 (0.979); STP22 (0.975); VPS28 (0.972); CHM7 (0.962); MIM2 (0.93); MOH1 (0.912); BRO1 (0.911); DOA4 (0.898); VPS27 (0.868); SNF8 (0.805); MIM1 (0.746)

Homologues (species, bitscore): CHMP1A (Homo sapiens, 170.6); Chmp1a (Mus musculus, 171.0); chmp1a (Danio rerio, 160.2); chmp1a (Xenopus tropicalis, 170.2); Chmp1 (Drosophila melanogaster, 151.0); did-2 (Caenorhabditis elegans, 149.1); VPS46.2 (Arabidopsis thaliana, 127.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:493607-494221:+ gene-YKR035W-A_AKU4011 rna-NM_001184309.3_AKU4011 cds-NP_012961.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:149256-149870:- gene-YKR035W-A_BG1 rna-NM_001184309.3_BG1 cds-NP_012961.3_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:515786-516400:+ gene-YKR035W-A_Bruggeman rna-NM_001184309.3_Bruggeman cds-NP_012961.3_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:511034-511648:+ gene-YKR035W-A_CAT1 rna-NM_001184309.3_CAT1 cds-NP_012961.3_CAT1 99.1 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:506347-506961:+ gene-YKR035W-A_CBS1585 rna-NM_001184309.3_CBS1585 cds-NP_012961.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:505188-505802:+ gene-YKR035W-A_CBS436 rna-NM_001184309.3_CBS436 cds-NP_012961.3_CBS436 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:490508-491122:+ gene-YKR035W-A_CBS6412 rna-NM_001184309.3_CBS6412 cds-NP_012961.3_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:506176-506790:+ gene-YKR035W-A_CBS6413 rna-NM_001184309.3_CBS6413 cds-NP_012961.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:507681-508331:+ gene-YKR035W-A_CENPK1137D rna-NM_001184309.3_CENPK1137D cds-NP_012961.3_CENPK1137D 94.0 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:503873-504487:+ gene-YKR035W-A_EthanolRed rna-NM_001184309.3_EthanolRed cds-NP_012961.3_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:507006-507620:+ gene-YKR035W-A_FaliES1 rna-NM_001184309.3_FaliES1 cds-NP_012961.3_FaliES1 99.5 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000077.1:46125-46739:- gene-YKR035W-A_JAY291 rna-NM_001184309.3_JAY291 cds-NP_012961.3_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:515936-516550:+ gene-YKR035W-A_MUCL30387 rna-NM_001184309.3_MUCL30387 cds-NP_012961.3_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:510550-511164:+ gene-YKR035W-A_MUCL30388 rna-NM_001184309.3_MUCL30388 cds-NP_012961.3_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:505665-506279:+ gene-YKR035W-A_MUCL39482 rna-NM_001184309.3_MUCL39482 cds-NP_012961.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:511704-512318:+ gene-YKR035W-A_MUCL42920 rna-NM_001184309.3_MUCL42920 cds-NP_012961.3_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:507928-508542:+ gene-YKR035W-A_NCIM3186 rna-NM_001184309.3_NCIM3186 cds-NP_012961.3_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:505871-506485:+ gene-YKR035W-A_NCYC1407 rna-NM_001184309.3_NCYC1407 cds-NP_012961.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:530872-531486:+ gene-YKR035W-A_PE2H3 rna-NM_001184309.3_PE2H3 cds-NP_012961.3_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:515595-516209:+ gene-YKR035W-A_PE2H4 rna-NM_001184309.3_PE2H4 cds-NP_012961.3_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:507939-508553:+ gene-YKR035W-A_S288C rna-NM_001184309.3_S288C cds-NP_012961.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000078.1:5190-5804:- gene-YKR035W-A_SA1 rna-NM_001184309.3_SA1 cds-NP_012961.3_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:506259-506873:+ gene-YKR035W-A_ThermosaccDry rna-NM_001184309.3_ThermosaccDry cds-NP_012961.3_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:505892-506506:+ gene-YKR035W-A_VR1 rna-NM_001184309.3_VR1 cds-NP_012961.3_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:504306-504920:+ gene-YKR035W-A_ZTW1 rna-NM_001184309.3_ZTW1 cds-NP_012961.3_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:529592-530206:+ gene-YKR035W-A_Sparadoxus rna-NM_001184309.3_Sparadoxus cds-NP_012961.3_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files