Gene name: DIA2
Reference locus (S288C): YOR080W
Gene biotype: protein_coding
Description: Protein DIA2; Origin-binding F-box protein; forms SCF ubiquitin ligase complex with Skp1p and Cdc53p; functions in ubiquitination of silent chromatin structural protein Sir4p; required to target Cdc6p for destruction during G1 phase; required for deactivation of Rad53 checkpoint kinase, completion of DNA replication during recovery from DNA damage, assembly of RSC complex, RSC-mediated transcription regulation, and nucleosome positioning; involved in invasive and pseudohyphal growth; Belongs to the DIA2 family
Top 10 interactors (score): MRC1 (0.977); SKP1 (0.971); CDC53 (0.96); CTF4 (0.941); CDC45 (0.863); CSM3 (0.859); SLD5 (0.849); MCM2 (0.827); SGS1 (0.798); MCM7 (0.776); RTT101 (0.769); YRA1 (0.763); RRM3 (0.744); TOM1 (0.727); RAD53 (0.725); RAD9 (0.725); TOF1 (0.723); RAD24 (0.713); BUD26 (0.697); YLR232W (0.696)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:458943-461141:+ | gene-YOR080W_AKU4011 | rna-NM_001183499.1_AKU4011 | cds-NP_014723.2_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:118554-120752:- | gene-YOR080W_BG1 | rna-NM_001183499.1_BG1 | cds-NP_014723.2_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:461661-463859:+ | gene-YOR080W_Bruggeman | rna-NM_001183499.1_Bruggeman | cds-NP_014723.2_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:460428-462626:+ | gene-YOR080W_CAT1 | rna-NM_001183499.1_CAT1 | cds-NP_014723.2_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:453662-455860:+ | gene-YOR080W_CBS1585 | rna-NM_001183499.1_CBS1585 | cds-NP_014723.2_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:458461-460659:+ | gene-YOR080W_CBS436 | rna-NM_001183499.1_CBS436 | cds-NP_014723.2_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:452952-455150:+ | gene-YOR080W_CBS6412 | rna-NM_001183499.1_CBS6412 | cds-NP_014723.2_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:460269-462467:+ | gene-YOR080W_CBS6413 | rna-NM_001183499.1_CBS6413 | cds-NP_014723.2_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:474591-476789:+ | gene-YOR080W_CENPK1137D | rna-NM_001183499.1_CENPK1137D | cds-NP_014723.2_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:455654-457852:+ | gene-YOR080W_EthanolRed | rna-NM_001183499.1_EthanolRed | cds-NP_014723.2_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:458983-461181:+ | gene-YOR080W_FaliES1 | rna-NM_001183499.1_FaliES1 | cds-NP_014723.2_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000231.1:10805-13003:- | gene-YOR080W_JAY291 | rna-NM_001183499.1_JAY291 | cds-NP_014723.2_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:466444-468642:+ | gene-YOR080W_MUCL30387 | rna-NM_001183499.1_MUCL30387 | cds-NP_014723.2_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:471101-473299:+ | gene-YOR080W_MUCL30388 | rna-NM_001183499.1_MUCL30388 | cds-NP_014723.2_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:461377-463575:+ | gene-YOR080W_MUCL39482 | rna-NM_001183499.1_MUCL39482 | cds-NP_014723.2_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:476922-479120:+ | gene-YOR080W_MUCL42920 | rna-NM_001183499.1_MUCL42920 | cds-NP_014723.2_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:474483-476681:+ | gene-YOR080W_NCIM3186 | rna-NM_001183499.1_NCIM3186 | cds-NP_014723.2_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:468049-470247:+ | gene-YOR080W_NCYC1407 | rna-NM_001183499.1_NCYC1407 | cds-NP_014723.2_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:466697-468895:+ | gene-YOR080W_PE2H3 | rna-NM_001183499.1_PE2H3 | cds-NP_014723.2_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:477073-479271:+ | gene-YOR080W_PE2H4 | rna-NM_001183499.1_PE2H4 | cds-NP_014723.2_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:474594-476792:+ | gene-YOR080W_S288C | rna-NM_001183499.1_S288C | cds-NP_014723.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000091.1:10834-13032:- | gene-YOR080W_SA1 | rna-NM_001183499.1_SA1 | cds-NP_014723.2_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:458139-460337:+ | gene-YOR080W_ThermosaccDry | rna-NM_001183499.1_ThermosaccDry | cds-NP_014723.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:459637-461835:+ | gene-YOR080W_VR1 | rna-NM_001183499.1_VR1 | cds-NP_014723.2_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:192136-194333:+ | gene-YOR080W_ZTW1 | rna-NM_001183499.1_ZTW1 | cds-NP_014723.2_ZTW1 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:463771-465972:+ | gene-YOR080W_Sparadoxus | rna-NM_001183499.1_Sparadoxus | cds-NP_014723.2_Sparadoxus | 87.5 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |