DGR2 (YKL121W)


Gene profile

Gene name: DGR2
Reference locus (S288C): YKL121W
Gene biotype: protein_coding

Description: Protein of unknown function; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally elongated buds; DGR2 has a paralog, YMR102C, that arose from the whole genome duplication; Belongs to the WD repeat DGR2 family

Top 10 interactors (score): DGR1 (0.895); ROT2 (0.816); EIS1 (0.692); LAM4 (0.619); HCR1 (0.617); SIP3 (0.581); BUD21 (0.574); LOC1 (0.573); SCO1 (0.568); YDL124W (0.567); YPT31 (0.552); YPT32 (0.552); GET3 (0.515); PGM2 (0.51); ENV7 (0.496); ARP3 (0.491); YRA1 (0.491); PGM1 (0.483); YER156C (0.48); LSP1 (0.48)

Homologues (species, bitscore): WDR44 (Homo sapiens, 143.7); Wdr44 (Mus musculus, 142.9); WDR44 (Danio rerio, 135.6); wdr44 (Xenopus tropicalis, 142.1); CG34133 (Drosophila melanogaster, 138.7); sym-4 (Caenorhabditis elegans, 154.8); AT3G15470 (Arabidopsis thaliana, 127.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:200719-203277:+ gene-YKL121W_AKU4011 rna-NM_001179687.1_AKU4011 cds-NP_012801.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:177841-180399:+ gene-YKL121W_BG1 rna-NM_001179687.1_BG1 cds-NP_012801.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:218632-221190:+ gene-YKL121W_Bruggeman rna-NM_001179687.1_Bruggeman cds-NP_012801.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:213687-216245:+ gene-YKL121W_CAT1 rna-NM_001179687.1_CAT1 cds-NP_012801.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:212952-215510:+ gene-YKL121W_CBS1585 rna-NM_001179687.1_CBS1585 cds-NP_012801.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:211539-214097:+ gene-YKL121W_CBS436 rna-NM_001179687.1_CBS436 cds-NP_012801.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:197580-200138:+ gene-YKL121W_CBS6412 rna-NM_001179687.1_CBS6412 cds-NP_012801.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:213415-215973:+ gene-YKL121W_CBS6413 rna-NM_001179687.1_CBS6413 cds-NP_012801.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:213783-216341:+ gene-YKL121W_CENPK1137D rna-NM_001179687.1_CENPK1137D cds-NP_012801.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:211449-214007:+ gene-YKL121W_EthanolRed rna-NM_001179687.1_EthanolRed cds-NP_012801.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:212262-214820:+ gene-YKL121W_FaliES1 rna-NM_001179687.1_FaliES1 cds-NP_012801.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:34558-37116:+ gene-YKL121W_JAY291 rna-NM_001179687.1_JAY291 cds-NP_012801.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:220453-223011:+ gene-YKL121W_MUCL30387 rna-NM_001179687.1_MUCL30387 cds-NP_012801.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:214824-217382:+ gene-YKL121W_MUCL30388 rna-NM_001179687.1_MUCL30388 cds-NP_012801.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:212744-215302:+ gene-YKL121W_MUCL39482 rna-NM_001179687.1_MUCL39482 cds-NP_012801.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:217120-219678:+ gene-YKL121W_MUCL42920 rna-NM_001179687.1_MUCL42920 cds-NP_012801.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:214131-216689:+ gene-YKL121W_NCIM3186 rna-NM_001179687.1_NCIM3186 cds-NP_012801.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:212926-215484:+ gene-YKL121W_NCYC1407 rna-NM_001179687.1_NCYC1407 cds-NP_012801.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:220027-222585:+ gene-YKL121W_PE2H3 rna-NM_001179687.1_PE2H3 cds-NP_012801.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:216310-218868:+ gene-YKL121W_PE2H4 rna-NM_001179687.1_PE2H4 cds-NP_012801.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:214142-216700:+ gene-YKL121W_S288C rna-NM_001179687.1_S288C cds-NP_012801.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:130267-132825:+ gene-YKL121W_SA1 rna-NM_001179687.1_SA1 cds-NP_012801.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:212962-215520:+ gene-YKL121W_ThermosaccDry rna-NM_001179687.1_ThermosaccDry cds-NP_012801.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:212278-214836:+ gene-YKL121W_VR1 rna-NM_001179687.1_VR1 cds-NP_012801.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:211494-214052:+ gene-YKL121W_ZTW1 rna-NM_001179687.1_ZTW1 cds-NP_012801.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:228774-231332:+ gene-YKL121W_Sparadoxus rna-NM_001179687.1_Sparadoxus cds-NP_012801.1_Sparadoxus 89.2 100.0 Verified 1 1 1 False True False False False

Additional files