DGA1 (YOR245C)


Gene profile

Gene name: DGA1
Reference locus (S288C): YOR245C
Gene biotype: protein_coding

Description: Diacylglycerol O-acyltransferase 1; Diacylglycerol acyltransferase; catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor; Lro1p and Dga1p can O-acylate ceramides; localized to lipid particles

Top 10 interactors (score): LRO1 (0.999); ARE2 (0.998); PAH1 (0.997); TGL3 (0.995); TGL4 (0.992); TGL5 (0.992); ARE1 (0.99); YJU3 (0.982); LPP1 (0.975); DPP1 (0.972); TGL2 (0.955); TGL1 (0.945); PHM8 (0.939); OLE1 (0.936); DGK1 (0.933); ATG15 (0.908); FAT1 (0.906); ALE1 (0.903); SLC1 (0.902); ACC1 (0.892)

Homologues (species, bitscore): MOGAT2 (Homo sapiens, 213.8); Mogat1 (Mus musculus, 218.0); mogat2 (Danio rerio, 203.0); mogat1 (Xenopus tropicalis, 208.8); CG1942 (Drosophila melanogaster, 156.8); K07B1.4 (Caenorhabditis elegans, 198.7); DGAT2 (Arabidopsis thaliana, 106.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:784848-786104:- gene-YOR245C_AKU4011 rna-NM_001183664.1_AKU4011 cds-NP_014888.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:186888-188144:- gene-YOR245C_BG1 rna-NM_001183664.1_BG1 cds-NP_014888.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:770315-771571:- gene-YOR245C_Bruggeman rna-NM_001183664.1_Bruggeman cds-NP_014888.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:770966-772222:- gene-YOR245C_CAT1 rna-NM_001183664.1_CAT1 cds-NP_014888.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:767837-769093:- gene-YOR245C_CBS1585 rna-NM_001183664.1_CBS1585 cds-NP_014888.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:766532-767788:- gene-YOR245C_CBS436 rna-NM_001183664.1_CBS436 cds-NP_014888.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:764956-766212:- gene-YOR245C_CBS6412 rna-NM_001183664.1_CBS6412 cds-NP_014888.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:773596-774852:- gene-YOR245C_CBS6413 rna-NM_001183664.1_CBS6413 cds-NP_014888.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:793839-795095:- gene-YOR245C_CENPK1137D rna-NM_001183664.1_CENPK1137D cds-NP_014888.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:760968-762224:- gene-YOR245C_EthanolRed rna-NM_001183664.1_EthanolRed cds-NP_014888.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:766367-767623:- gene-YOR245C_FaliES1 rna-NM_001183664.1_FaliES1 cds-NP_014888.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:59214-60470:+ gene-YOR245C_JAY291 rna-NM_001183664.1_JAY291 cds-NP_014888.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:774586-775842:- gene-YOR245C_MUCL30387 rna-NM_001183664.1_MUCL30387 cds-NP_014888.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:781704-782960:- gene-YOR245C_MUCL30388 rna-NM_001183664.1_MUCL30388 cds-NP_014888.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:775167-776423:- gene-YOR245C_MUCL39482 rna-NM_001183664.1_MUCL39482 cds-NP_014888.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:784756-786012:- gene-YOR245C_MUCL42920 rna-NM_001183664.1_MUCL42920 cds-NP_014888.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:793965-795221:- gene-YOR245C_NCIM3186 rna-NM_001183664.1_NCIM3186 cds-NP_014888.1_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:775266-776522:- gene-YOR245C_NCYC1407 rna-NM_001183664.1_NCYC1407 cds-NP_014888.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:774568-775824:- gene-YOR245C_PE2H3 rna-NM_001183664.1_PE2H3 cds-NP_014888.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:784945-786201:- gene-YOR245C_PE2H4 rna-NM_001183664.1_PE2H4 cds-NP_014888.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:794076-795332:- gene-YOR245C_S288C rna-NM_001183664.1_S288C cds-NP_014888.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:204069-205325:- gene-YOR245C_SA1 rna-NM_001183664.1_SA1 cds-NP_014888.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:765550-766806:- gene-YOR245C_ThermosaccDry rna-NM_001183664.1_ThermosaccDry cds-NP_014888.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:829008-830264:- gene-YOR245C_VR1 rna-NM_001183664.1_VR1 cds-NP_014888.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:498466-499722:- gene-YOR245C_ZTW1 rna-NM_001183664.1_ZTW1 cds-NP_014888.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:771466-772722:- gene-YOR245C_Sparadoxus rna-NM_001183664.1_Sparadoxus cds-NP_014888.1_Sparadoxus 90.2 99.9 Verified 1 1 1 False True False False False

Additional files