Gene name: DFG10
Reference locus (S288C): YIL049W
Gene biotype: protein_coding
Description: Probable polyprenol reductase; catalyzes conversion of polyprenol to dolichol, the precursor for N-glycosylation; involved in filamentous growth; mutations in human homolog SRD5A3 confer CDG (Congenital Disorders of Glycosylation); human SRD5A3 can complement yeast null mutant
Top 10 interactors (score): SEC59 (0.995); RER2 (0.947); NUS1 (0.935); ALG6 (0.915); SRT1 (0.911); TSC13 (0.876); PRM6 (0.855); JLP2 (0.804); CAX4 (0.792); DPM1 (0.783); ALG5 (0.775); YJL175W (0.766); ALG11 (0.717); DBR1 (0.712); ALG7 (0.669); ANP1 (0.648); PRC1 (0.613); ERG9 (0.61); ALG8 (0.589); ERG20 (0.569)
Homologues (species, bitscore): SRD5A3 (Homo sapiens, 58.2); Srd5a3 (Mus musculus, 55.8); srd5a3 (Danio rerio, 67.0); srd5a3 (Xenopus tropicalis, 57.8); CG7840 (Drosophila melanogaster, 75.9); B0024.13 (Caenorhabditis elegans, 73.2); AT1G72590 (Arabidopsis thaliana, 63.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:256991-257752:+ | gene-YIL049W_AKU4011 | rna-NM_001179399.1_AKU4011 | cds-NP_012215.1_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:118418-119179:+ | gene-YIL049W_BG1 | rna-NM_001179399.1_BG1 | cds-NP_012215.1_BG1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:263242-264003:+ | gene-YIL049W_Bruggeman | rna-NM_001179399.1_Bruggeman | cds-NP_012215.1_Bruggeman | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:251153-251914:+ | gene-YIL049W_CAT1 | rna-NM_001179399.1_CAT1 | cds-NP_012215.1_CAT1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:256816-257577:+ | gene-YIL049W_CBS1585 | rna-NM_001179399.1_CBS1585 | cds-NP_012215.1_CBS1585 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:252116-252877:+ | gene-YIL049W_CBS436 | rna-NM_001179399.1_CBS436 | cds-NP_012215.1_CBS436 | 98.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:253431-254192:+ | gene-YIL049W_CBS6412 | rna-NM_001179399.1_CBS6412 | cds-NP_012215.1_CBS6412 | 98.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:248982-249743:+ | gene-YIL049W_CBS6413 | rna-NM_001179399.1_CBS6413 | cds-NP_012215.1_CBS6413 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:251857-252628:+ | gene-YIL049W_CENPK1137D | rna-NM_001179399.1_CENPK1137D | cds-NP_012215.1_CENPK1137D | 94.8 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:240905-241666:+ | gene-YIL049W_EthanolRed | rna-NM_001179399.1_EthanolRed | cds-NP_012215.1_EthanolRed | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:258444-259205:+ | gene-YIL049W_FaliES1 | rna-NM_001179399.1_FaliES1 | cds-NP_012215.1_FaliES1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000365.1:39674-40435:- | gene-YIL049W_JAY291 | rna-NM_001179399.1_JAY291 | cds-NP_012215.1_JAY291 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:260134-260895:+ | gene-YIL049W_MUCL30387 | rna-NM_001179399.1_MUCL30387 | cds-NP_012215.1_MUCL30387 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:256737-257498:+ | gene-YIL049W_MUCL30388 | rna-NM_001179399.1_MUCL30388 | cds-NP_012215.1_MUCL30388 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:257659-258420:+ | gene-YIL049W_MUCL39482 | rna-NM_001179399.1_MUCL39482 | cds-NP_012215.1_MUCL39482 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:260790-261551:+ | gene-YIL049W_MUCL42920 | rna-NM_001179399.1_MUCL42920 | cds-NP_012215.1_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:260158-260919:+ | gene-YIL049W_NCIM3186 | rna-NM_001179399.1_NCIM3186 | cds-NP_012215.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:261932-262693:+ | gene-YIL049W_NCYC1407 | rna-NM_001179399.1_NCYC1407 | cds-NP_012215.1_NCYC1407 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:255166-255927:+ | gene-YIL049W_PE2H3 | rna-NM_001179399.1_PE2H3 | cds-NP_012215.1_PE2H3 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:249886-250647:+ | gene-YIL049W_PE2H4 | rna-NM_001179399.1_PE2H4 | cds-NP_012215.1_PE2H4 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:260158-260919:+ | gene-YIL049W_S288C | rna-NM_001179399.1_S288C | cds-NP_012215.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:65257-66018:- | gene-YIL049W_SA1 | rna-NM_001179399.1_SA1 | cds-NP_012215.1_SA1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:257113-257874:+ | gene-YIL049W_ThermosaccDry | rna-NM_001179399.1_ThermosaccDry | cds-NP_012215.1_ThermosaccDry | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:254282-255043:+ | gene-YIL049W_VR1 | rna-NM_001179399.1_VR1 | cds-NP_012215.1_VR1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:230956-231717:+ | gene-YIL049W_ZTW1 | rna-NM_001179399.1_ZTW1 | cds-NP_012215.1_ZTW1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:253073-253834:+ | gene-YIL049W_Sparadoxus | rna-NM_001179399.1_Sparadoxus | cds-NP_012215.1_Sparadoxus | 89.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |