DEG1 (YFL001W)


Gene profile

Gene name: DEG1
Reference locus (S288C): YFL001W
Gene biotype: protein_coding

Description: tRNA:pseudouridine synthase; introduces pseudouridines at position 38 or 39 in tRNA; also responsible for pseudouracil modification of some mRNAs; important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm; non-essential for viability

Top 10 interactors (score): PUS7 (0.976); PUS4 (0.975); TRM1 (0.969); PUS2 (0.964); TRM7 (0.964); TRM10 (0.952); SSM4 (0.915); NCL1 (0.905); TRM5 (0.902); PUS6 (0.898); SEC62 (0.896); RIB2 (0.891); URM1 (0.889); PUS9 (0.889); PUS5 (0.879); ELP3 (0.878); SUA5 (0.871); TRM82 (0.864); MOD5 (0.849); MATALPHA2 (0.843)

Homologues (species, bitscore): PUS3 (Homo sapiens, 264.2); Pus3 (Mus musculus, 266.9); pus3 (Danio rerio, 250.4); pus3 (Xenopus tropicalis, 251.9); CG3045 (Drosophila melanogaster, 218.4); tag-124 (Caenorhabditis elegans, 202.2); AT1G34150 (Arabidopsis thaliana, 207.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:137577-138905:+ gene-YFL001W_AKU4011 rna-NM_001179965.1_AKU4011 cds-NP_116655.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000079.1:22472-23800:+ gene-YFL001W_BG1 rna-NM_001179965.1_BG1 cds-NP_116655.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:137143-138471:+ gene-YFL001W_Bruggeman rna-NM_001179965.1_Bruggeman cds-NP_116655.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:142306-143634:+ gene-YFL001W_CAT1 rna-NM_001179965.1_CAT1 cds-NP_116655.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:138402-139730:+ gene-YFL001W_CBS1585 rna-NM_001179965.1_CBS1585 cds-NP_116655.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:112249-113577:+ gene-YFL001W_CBS436 rna-NM_001179965.1_CBS436 cds-NP_116655.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:138143-139471:+ gene-YFL001W_CBS6412 rna-NM_001179965.1_CBS6412 cds-NP_116655.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:140653-141981:+ gene-YFL001W_CBS6413 rna-NM_001179965.1_CBS6413 cds-NP_116655.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:143265-144593:+ gene-YFL001W_CENPK1137D rna-NM_001179965.1_CENPK1137D cds-NP_116655.1_CENPK1137D 99.2 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:136563-137891:+ gene-YFL001W_EthanolRed rna-NM_001179965.1_EthanolRed cds-NP_116655.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:138210-139538:+ gene-YFL001W_FaliES1 rna-NM_001179965.1_FaliES1 cds-NP_116655.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000451.1:2316-3644:+ gene-YFL001W_JAY291 rna-NM_001179965.1_JAY291 cds-NP_116655.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:138774-140102:+ gene-YFL001W_MUCL30387 rna-NM_001179965.1_MUCL30387 cds-NP_116655.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:136751-138079:+ gene-YFL001W_MUCL30388 rna-NM_001179965.1_MUCL30388 cds-NP_116655.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:136846-138174:+ gene-YFL001W_MUCL39482 rna-NM_001179965.1_MUCL39482 cds-NP_116655.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:136110-137438:+ gene-YFL001W_MUCL42920 rna-NM_001179965.1_MUCL42920 cds-NP_116655.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:147130-148458:+ gene-YFL001W_NCIM3186 rna-NM_001179965.1_NCIM3186 cds-NP_116655.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:137861-139189:+ gene-YFL001W_NCYC1407 rna-NM_001179965.1_NCYC1407 cds-NP_116655.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:156926-158254:+ gene-YFL001W_PE2H3 rna-NM_001179965.1_PE2H3 cds-NP_116655.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:156474-157802:+ gene-YFL001W_PE2H4 rna-NM_001179965.1_PE2H4 cds-NP_116655.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:147131-148459:+ gene-YFL001W_S288C rna-NM_001179965.1_S288C cds-NP_116655.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:175767-177095:- gene-YFL001W_SA1 rna-NM_001179965.1_SA1 cds-NP_116655.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:137370-138698:+ gene-YFL001W_ThermosaccDry rna-NM_001179965.1_ThermosaccDry cds-NP_116655.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:152573-153901:+ gene-YFL001W_VR1 rna-NM_001179965.1_VR1 cds-NP_116655.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:67819-69147:+ gene-YFL001W_ZTW1 rna-NM_001179965.1_ZTW1 cds-NP_116655.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:161017-162345:+ gene-YFL001W_Sparadoxus rna-NM_001179965.1_Sparadoxus cds-NP_116655.1_Sparadoxus 89.9 100.0 Verified 1 1 1 False True False False False

Additional files