Gene name: DED1
Reference locus (S288C): YOR204W
Gene biotype: protein_coding
Description: ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase; required for translation initiation of all yeast mRNAs; binds to mRNA cap-associated factors, and binding stimulates Ded1p RNA-dependent ATPase activity; mutation in human homolog DBY is associated with male infertility; human homolog DDX3X complements ded1 null mutation; DED1 has a paralog, DBP1, that arose from the whole genome duplication
Top 10 interactors (score): DBP1 (0.999); CDC33 (0.998); TIF4631 (0.996); RPG1 (0.986); SNU114 (0.974); PRP6 (0.972); CEF1 (0.969); TIF4632 (0.968); TIF35 (0.964); PAB1 (0.959); DHR2 (0.955); PRT1 (0.949); TIF3 (0.948); NIP1 (0.938); PRP43 (0.934); NOG1 (0.925); XRN1 (0.92); SCD6 (0.893); DHH1 (0.892); TIF1 (0.883)
Homologues (species, bitscore): DDX3X (Homo sapiens, 589.7); D1Pas1 (Mus musculus, 590.1); ddx3 (Danio rerio, 597.0); ddx3x (Xenopus tropicalis, 589.0); bel (Drosophila melanogaster, 593.2); laf-1 (Caenorhabditis elegans, 522.7); AT3G58510 (Arabidopsis thaliana, 573.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:713694-715508:+ | gene-YOR204W_AKU4011 | rna-NM_001183623.3_AKU4011 | cds-NP_014847.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:115733-117547:+ | gene-YOR204W_BG1 | rna-NM_001183623.3_BG1 | cds-NP_014847.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:698525-700342:+ | gene-YOR204W_Bruggeman | rna-NM_001183623.3_Bruggeman | cds-NP_014847.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:699806-701620:+ | gene-YOR204W_CAT1 | rna-NM_001183623.3_CAT1 | cds-NP_014847.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:696681-698495:+ | gene-YOR204W_CBS1585 | rna-NM_001183623.3_CBS1585 | cds-NP_014847.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:695371-697185:+ | gene-YOR204W_CBS436 | rna-NM_001183623.3_CBS436 | cds-NP_014847.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:693799-695613:+ | gene-YOR204W_CBS6412 | rna-NM_001183623.3_CBS6412 | cds-NP_014847.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:702438-704252:+ | gene-YOR204W_CBS6413 | rna-NM_001183623.3_CBS6413 | cds-NP_014847.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:722676-724490:+ | gene-YOR204W_CENPK1137D | rna-NM_001183623.3_CENPK1137D | cds-NP_014847.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:689824-691638:+ | gene-YOR204W_EthanolRed | rna-NM_001183623.3_EthanolRed | cds-NP_014847.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:695221-697035:+ | gene-YOR204W_FaliES1 | rna-NM_001183623.3_FaliES1 | cds-NP_014847.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:129714-131528:- | gene-YOR204W_JAY291 | rna-NM_001183623.3_JAY291 | cds-NP_014847.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:702490-704304:+ | gene-YOR204W_MUCL30387 | rna-NM_001183623.3_MUCL30387 | cds-NP_014847.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:709907-711721:+ | gene-YOR204W_MUCL30388 | rna-NM_001183623.3_MUCL30388 | cds-NP_014847.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:704010-705824:+ | gene-YOR204W_MUCL39482 | rna-NM_001183623.3_MUCL39482 | cds-NP_014847.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:713593-715407:+ | gene-YOR204W_MUCL42920 | rna-NM_001183623.3_MUCL42920 | cds-NP_014847.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:722800-724614:+ | gene-YOR204W_NCIM3186 | rna-NM_001183623.3_NCIM3186 | cds-NP_014847.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:704108-705922:+ | gene-YOR204W_NCYC1407 | rna-NM_001183623.3_NCYC1407 | cds-NP_014847.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:703505-705319:+ | gene-YOR204W_PE2H3 | rna-NM_001183623.3_PE2H3 | cds-NP_014847.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:713882-715696:+ | gene-YOR204W_PE2H4 | rna-NM_001183623.3_PE2H4 | cds-NP_014847.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:722911-724725:+ | gene-YOR204W_S288C | rna-NM_001183623.3_S288C | cds-NP_014847.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:132912-134726:+ | gene-YOR204W_SA1 | rna-NM_001183623.3_SA1 | cds-NP_014847.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:694406-696220:+ | gene-YOR204W_ThermosaccDry | rna-NM_001183623.3_ThermosaccDry | cds-NP_014847.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:757946-759760:+ | gene-YOR204W_VR1 | rna-NM_001183623.3_VR1 | cds-NP_014847.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:427319-429133:+ | gene-YOR204W_ZTW1 | rna-NM_001183623.3_ZTW1 | cds-NP_014847.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:700274-702094:+ | gene-YOR204W_Sparadoxus | rna-NM_001183623.3_Sparadoxus | cds-NP_014847.3_Sparadoxus | 93.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |