DDR48 (YMR173W)


Gene profile

Gene name: DDR48
Reference locus (S288C): YMR173W
Gene biotype: protein_coding

Description: Stress protein DDR48; DNA damage-responsive protein; expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): YMR173W-A (0.994); YDR193W (0.712); YHR112C (0.694); DDR2 (0.677); YBL036C (0.621); YML007C-A (0.62); HSP12 (0.588); YBL071C (0.573); YHR056W-A (0.573); YCR013C (0.573); GRE1 (0.572); YIM2 (0.569); YLR163W-A (0.569); YPR136C (0.569); YAL016C-B (0.569); YKL165C-A (0.569); YNL319W (0.565); YMR304C-A (0.558); YGP1 (0.552); GOT1 (0.53)

Homologues (species, bitscore): ENSDARP00000104633 (Danio rerio, 66.2); ENSXETP00000063577 (Xenopus tropicalis, 128.6); Muc91C (Drosophila melanogaster, 91.7); AT1G10390 (Arabidopsis thaliana, 100.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:648437-649739:+ gene-YMR173W_AKU4011 rna-NM_001182678.1_AKU4011 cds-NP_013897.1_AKU4011 70.0 86.3 Verified 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000068.1:23226-24392:- gene-YMR173W_BG1 rna-NM_001182678.1_BG1 cds-NP_013897.1_BG1 84.2 87.9 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:591365-593225:+ gene-YMR173W_Bruggeman rna-NM_001182678.1_Bruggeman cds-NP_013897.1_Bruggeman 68.5 100.0 Unannotated 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:595118-596641:+ gene-YMR173W_CAT1 rna-NM_001182678.1_CAT1 cds-NP_013897.1_CAT1 82.2 99.3 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:581118-582182:+ gene-YMR173W_CBS1585 rna-NM_001182678.1_CBS1585 cds-NP_013897.1_CBS1585 71.1 78.4 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:584984-586255:+ gene-YMR173W_CBS436 rna-NM_001182678.1_CBS436 cds-NP_013897.1_CBS436 91.9 96.6 Mismatch 1 1 0 False False False True False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:693323-694724:+ gene-YMR173W_CBS6412 rna-NM_001182678.1_CBS6412 cds-NP_013897.1_CBS6412 71.9 93.8 Unannotated 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:579668-581326:+ gene-YMR173W_CBS6413 rna-NM_001182678.1_CBS6413 cds-NP_013897.1_CBS6413 72.9 99.3 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:603592-604527:+ gene-YMR173W_CENPK1137D rna-NM_001182678.1_CENPK1137D cds-NP_013897.1_CENPK1137D 72.3 72.3 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:641294-642558:+ gene-YMR173W_EthanolRed rna-NM_001182678.1_EthanolRed cds-NP_013897.1_EthanolRed 77.9 88.6 Verified 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:586448-587498:+ gene-YMR173W_FaliES1 rna-NM_001182678.1_FaliES1 cds-NP_013897.1_FaliES1 71.0 77.4 Unannotated 1 1 0 False False False True False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000201.1:1-829:- gene-YMR173W_JAY291 rna-NM_001182678.1_JAY291 cds-NP_013897.1_JAY291 59.7 62.2 Verified 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:586339-587641:+ gene-YMR173W_MUCL30387 rna-NM_001182678.1_MUCL30387 cds-NP_013897.1_MUCL30387 86.4 94.2 Verified 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:593370-594493:+ gene-YMR173W_MUCL30388 rna-NM_001182678.1_MUCL30388 cds-NP_013897.1_MUCL30388 80.6 84.9 Verified 1 1 0 False False True False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:581804-583234:+ gene-YMR173W_MUCL39482 rna-NM_001182678.1_MUCL39482 cds-NP_013897.1_MUCL39482 82.0 98.3 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:589349-590608:+ gene-YMR173W_MUCL42920 rna-NM_001182678.1_MUCL42920 cds-NP_013897.1_MUCL42920 74.9 86.7 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:608643-609935:+ gene-YMR173W_NCIM3186 rna-NM_001182678.1_NCIM3186 cds-NP_013897.1_NCIM3186 98.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:581506-582869:+ gene-YMR173W_NCYC1407 rna-NM_001182678.1_NCYC1407 cds-NP_013897.1_NCYC1407 74.3 90.8 Verified 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:591848-592756:+ gene-YMR173W_PE2H3 rna-NM_001182678.1_PE2H3 cds-NP_013897.1_PE2H3 69.6 70.3 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:592311-593582:+ gene-YMR173W_PE2H4 rna-NM_001182678.1_PE2H4 cds-NP_013897.1_PE2H4 88.4 94.8 Verified 1 1 0 False False False True False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:608689-609981:+ gene-YMR173W_S288C rna-NM_001182678.1_S288C cds-NP_013897.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000002.1:198129-199781:- gene-YMR173W_SA1 rna-NM_001182678.1_SA1 cds-NP_013897.1_SA1 76.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:582180-584152:+ gene-YMR173W_ThermosaccDry rna-NM_001182678.1_ThermosaccDry cds-NP_013897.1_ThermosaccDry 64.2 100.0 Verified 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:595674-597326:+ gene-YMR173W_VR1 rna-NM_001182678.1_VR1 cds-NP_013897.1_VR1 75.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:556803-556921:+ gene-YMR173W_ZTW1 rna-NM_001182678.1_ZTW1 cds-NP_013897.1_ZTW1 9.2 9.2 Mismatch 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:600474-602069:+ gene-YMR173W_Sparadoxus rna-NM_001182678.1_Sparadoxus cds-NP_013897.1_Sparadoxus 63.3 94.1 Verified 1 1 1 False True False False False

Additional files