Gene name: DCS2
Reference locus (S288C): YOR173W
Gene biotype: protein_coding
Description: Inactive diphosphatase DCS2; m(7)GpppX pyrophosphatase regulator; non-essential, stress induced regulatory protein; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway; mutant has increased aneuploidy tolerance; DCS2 has a paralog, DCS1, that arose from the whole genome duplication; Belongs to the HIT family
Top 10 interactors (score): DCS1 (0.999); SOL4 (0.994); MSC1 (0.993); RTN2 (0.987); GAD1 (0.975); TFS1 (0.975); TSL1 (0.975); GLC3 (0.969); OM45 (0.969); GCY1 (0.964); DDR2 (0.959); ALD3 (0.957); CTT1 (0.943); FMP16 (0.941); UIP4 (0.941); RTC3 (0.941); IGD1 (0.94); YLR345W (0.94); NNR1 (0.932); STF2 (0.928)
Homologues (species, bitscore): DCPS (Homo sapiens, 167.2); Dcps (Mus musculus, 167.2); dcps (Danio rerio, 162.5); dcps (Xenopus tropicalis, 157.9); CG2091 (Drosophila melanogaster, 179.5); dcs-1 (Caenorhabditis elegans, 143.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:654903-655964:+ | gene-YOR173W_AKU4011 | rna-NM_001183592.1_AKU4011 | cds-NP_014816.2_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:56657-57718:+ | gene-YOR173W_BG1 | rna-NM_001183592.1_BG1 | cds-NP_014816.2_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:638976-640037:+ | gene-YOR173W_Bruggeman | rna-NM_001183592.1_Bruggeman | cds-NP_014816.2_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:638995-640056:+ | gene-YOR173W_CAT1 | rna-NM_001183592.1_CAT1 | cds-NP_014816.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:637398-638459:+ | gene-YOR173W_CBS1585 | rna-NM_001183592.1_CBS1585 | cds-NP_014816.2_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:635692-636753:+ | gene-YOR173W_CBS436 | rna-NM_001183592.1_CBS436 | cds-NP_014816.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:635010-636071:+ | gene-YOR173W_CBS6412 | rna-NM_001183592.1_CBS6412 | cds-NP_014816.2_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:643691-644752:+ | gene-YOR173W_CBS6413 | rna-NM_001183592.1_CBS6413 | cds-NP_014816.2_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:657020-658081:+ | gene-YOR173W_CENPK1137D | rna-NM_001183592.1_CENPK1137D | cds-NP_014816.2_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:631106-632167:+ | gene-YOR173W_EthanolRed | rna-NM_001183592.1_EthanolRed | cds-NP_014816.2_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:635959-637020:+ | gene-YOR173W_FaliES1 | rna-NM_001183592.1_FaliES1 | cds-NP_014816.2_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000070.1:6522-7583:- | gene-YOR173W_JAY291 | rna-NM_001183592.1_JAY291 | cds-NP_014816.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:643783-644844:+ | gene-YOR173W_MUCL30387 | rna-NM_001183592.1_MUCL30387 | cds-NP_014816.2_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:650547-651608:+ | gene-YOR173W_MUCL30388 | rna-NM_001183592.1_MUCL30388 | cds-NP_014816.2_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:645239-646300:+ | gene-YOR173W_MUCL39482 | rna-NM_001183592.1_MUCL39482 | cds-NP_014816.2_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:654660-655721:+ | gene-YOR173W_MUCL42920 | rna-NM_001183592.1_MUCL42920 | cds-NP_014816.2_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:657153-658214:+ | gene-YOR173W_NCIM3186 | rna-NM_001183592.1_NCIM3186 | cds-NP_014816.2_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:645325-646386:+ | gene-YOR173W_NCYC1407 | rna-NM_001183592.1_NCYC1407 | cds-NP_014816.2_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:643836-644897:+ | gene-YOR173W_PE2H3 | rna-NM_001183592.1_PE2H3 | cds-NP_014816.2_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:654213-655274:+ | gene-YOR173W_PE2H4 | rna-NM_001183592.1_PE2H4 | cds-NP_014816.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:657264-658325:+ | gene-YOR173W_S288C | rna-NM_001183592.1_S288C | cds-NP_014816.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:73822-74883:+ | gene-YOR173W_SA1 | rna-NM_001183592.1_SA1 | cds-NP_014816.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:635142-636203:+ | gene-YOR173W_ThermosaccDry | rna-NM_001183592.1_ThermosaccDry | cds-NP_014816.2_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:698839-699900:+ | gene-YOR173W_VR1 | rna-NM_001183592.1_VR1 | cds-NP_014816.2_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:368593-369654:+ | gene-YOR173W_ZTW1 | rna-NM_001183592.1_ZTW1 | cds-NP_014816.2_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:640080-641141:+ | gene-YOR173W_Sparadoxus | rna-NM_001183592.1_Sparadoxus | cds-NP_014816.2_Sparadoxus | 91.2 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |