Gene name: DCS1
Reference locus (S288C): YLR270W
Gene biotype: protein_coding
Description: m7GpppX diphosphatase; Non-essential hydrolase involved in mRNA decapping; activates Xrn1p; may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; acts as inhibitor of neutral trehalase Nth1p; required for growth on glycerol medium; protein abundance increases in response to DNA replication stress; DCS1 has a paralog, DCS2, that arose from the whole genome duplication
Top 10 interactors (score): DCS2 (0.999); XRN1 (0.976); NTH1 (0.961); GRE3 (0.934); TFS1 (0.927); DCP2 (0.924); MSC1 (0.919); GAD1 (0.91); PNC1 (0.908); SOL4 (0.905); PGM2 (0.895); YLR345W (0.888); TSL1 (0.86); RAT1 (0.855); DHH1 (0.853); HNT2 (0.847); EMW1 (0.835); INO1 (0.835); RTC3 (0.82); GGA1 (0.811)
Homologues (species, bitscore): DCPS (Homo sapiens, 145.6); Dcps (Mus musculus, 144.4); dcps (Danio rerio, 158.7); dcps (Xenopus tropicalis, 151.4); CG2091 (Drosophila melanogaster, 168.7); dcs-1 (Caenorhabditis elegans, 150.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:629431-630483:+ | gene-YLR270W_AKU4011 | rna-NM_001182157.1_AKU4011 | cds-NP_013372.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:101398-102450:- | gene-YLR270W_BG1 | rna-NM_001182157.1_BG1 | cds-NP_013372.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:663692-664744:+ | gene-YLR270W_Bruggeman | rna-NM_001182157.1_Bruggeman | cds-NP_013372.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:662878-663930:+ | gene-YLR270W_CAT1 | rna-NM_001182157.1_CAT1 | cds-NP_013372.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:664926-665978:+ | gene-YLR270W_CBS1585 | rna-NM_001182157.1_CBS1585 | cds-NP_013372.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:649163-650215:+ | gene-YLR270W_CBS436 | rna-NM_001182157.1_CBS436 | cds-NP_013372.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:627901-628953:+ | gene-YLR270W_CBS6412 | rna-NM_001182157.1_CBS6412 | cds-NP_013372.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:665222-666274:+ | gene-YLR270W_CBS6413 | rna-NM_001182157.1_CBS6413 | cds-NP_013372.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:665762-666814:+ | gene-YLR270W_CENPK1137D | rna-NM_001182157.1_CENPK1137D | cds-NP_013372.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:623632-624684:+ | gene-YLR270W_EthanolRed | rna-NM_001182157.1_EthanolRed | cds-NP_013372.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:652463-653515:+ | gene-YLR270W_FaliES1 | rna-NM_001182157.1_FaliES1 | cds-NP_013372.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000136.1:5877-6929:- | gene-YLR270W_JAY291 | rna-NM_001182157.1_JAY291 | cds-NP_013372.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:664547-665599:+ | gene-YLR270W_MUCL30387 | rna-NM_001182157.1_MUCL30387 | cds-NP_013372.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:669314-670366:+ | gene-YLR270W_MUCL30388 | rna-NM_001182157.1_MUCL30388 | cds-NP_013372.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:665907-666959:+ | gene-YLR270W_MUCL39482 | rna-NM_001182157.1_MUCL39482 | cds-NP_013372.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:660693-661745:+ | gene-YLR270W_MUCL42920 | rna-NM_001182157.1_MUCL42920 | cds-NP_013372.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:681160-682212:+ | gene-YLR270W_NCIM3186 | rna-NM_001182157.1_NCIM3186 | cds-NP_013372.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:652895-653947:+ | gene-YLR270W_NCYC1407 | rna-NM_001182157.1_NCYC1407 | cds-NP_013372.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:656683-657735:+ | gene-YLR270W_PE2H3 | rna-NM_001182157.1_PE2H3 | cds-NP_013372.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:656427-657479:+ | gene-YLR270W_PE2H4 | rna-NM_001182157.1_PE2H4 | cds-NP_013372.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:681186-682238:+ | gene-YLR270W_S288C | rna-NM_001182157.1_S288C | cds-NP_013372.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:6123-7175:- | gene-YLR270W_SA1 | rna-NM_001182157.1_SA1 | cds-NP_013372.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:654416-655468:+ | gene-YLR270W_ThermosaccDry | rna-NM_001182157.1_ThermosaccDry | cds-NP_013372.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:665751-666803:+ | gene-YLR270W_VR1 | rna-NM_001182157.1_VR1 | cds-NP_013372.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:178715-179767:+ | gene-YLR270W_ZTW1 | rna-NM_001182157.1_ZTW1 | cds-NP_013372.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:640404-641456:+ | gene-YLR270W_Sparadoxus | rna-NM_001182157.1_Sparadoxus | cds-NP_013372.1_Sparadoxus | 92.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |