Gene name: DCP2
Reference locus (S288C): YNL118C
Gene biotype: protein_coding
Description: m7GpppN-mRNA hydrolase; Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex; removes 5' cap structure from mRNAs prior to their degradation; also enters nucleus and positively regulates transcription initiation; nudix hydrolase family member; forms cytoplasmic foci upon DNA replication stress; human homolog DCP2 complements yeast dcp2 thermosensitive mutant
Top 10 interactors (score): LSM1 (0.999); XRN1 (0.999); DCP1 (0.999); SCD6 (0.999); DHH1 (0.999); EDC3 (0.999); PAT1 (0.999); LSM4 (0.998); NAM7 (0.996); LSM3 (0.996); LSM7 (0.996); LSM2 (0.995); NNR1 (0.982); PAB1 (0.98); LSM5 (0.978); RAT1 (0.974); LSM6 (0.973); CDC33 (0.971); DCS1 (0.924); RAI1 (0.923)
Homologues (species, bitscore): DCP2 (Homo sapiens, 165.2); Dcp2 (Mus musculus, 166.0); dcp2 (Danio rerio, 160.2); dcp2 (Xenopus tropicalis, 154.1); DCP2 (Drosophila melanogaster, 152.1); dcap-2 (Caenorhabditis elegans, 131.0); DCP2 (Arabidopsis thaliana, 153.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:396334-399246:- | gene-YNL118C_AKU4011 | rna-NM_001182956.1_AKU4011 | cds-NP_014281.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:300331-303240:- | gene-YNL118C_BG1 | rna-NM_001182956.1_BG1 | cds-NP_014281.1_BG1 | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:406800-409712:- | gene-YNL118C_Bruggeman | rna-NM_001182956.1_Bruggeman | cds-NP_014281.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:450100-453009:- | gene-YNL118C_CAT1 | rna-NM_001182956.1_CAT1 | cds-NP_014281.1_CAT1 | 99.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:396954-399866:- | gene-YNL118C_CBS1585 | rna-NM_001182956.1_CBS1585 | cds-NP_014281.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:465366-468275:- | gene-YNL118C_CBS436 | rna-NM_001182956.1_CBS436 | cds-NP_014281.1_CBS436 | 99.1 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:392407-395319:- | gene-YNL118C_CBS6412 | rna-NM_001182956.1_CBS6412 | cds-NP_014281.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:393372-396284:- | gene-YNL118C_CBS6413 | rna-NM_001182956.1_CBS6413 | cds-NP_014281.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:396502-399414:- | gene-YNL118C_CENPK1137D | rna-NM_001182956.1_CENPK1137D | cds-NP_014281.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:393324-396236:- | gene-YNL118C_EthanolRed | rna-NM_001182956.1_EthanolRed | cds-NP_014281.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:389226-392138:- | gene-YNL118C_FaliES1 | rna-NM_001182956.1_FaliES1 | cds-NP_014281.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000021.1:45608-48517:- | gene-YNL118C_JAY291 | rna-NM_001182956.1_JAY291 | cds-NP_014281.1_JAY291 | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:403219-406131:- | gene-YNL118C_MUCL30387 | rna-NM_001182956.1_MUCL30387 | cds-NP_014281.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:438398-441310:- | gene-YNL118C_MUCL30388 | rna-NM_001182956.1_MUCL30388 | cds-NP_014281.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:394233-397145:- | gene-YNL118C_MUCL39482 | rna-NM_001182956.1_MUCL39482 | cds-NP_014281.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:397473-400385:- | gene-YNL118C_MUCL42920 | rna-NM_001182956.1_MUCL42920 | cds-NP_014281.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:402621-405533:- | gene-YNL118C_NCIM3186 | rna-NM_001182956.1_NCIM3186 | cds-NP_014281.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:396365-399277:- | gene-YNL118C_NCYC1407 | rna-NM_001182956.1_NCYC1407 | cds-NP_014281.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:395357-398266:- | gene-YNL118C_PE2H3 | rna-NM_001182956.1_PE2H3 | cds-NP_014281.1_PE2H3 | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:394763-397672:- | gene-YNL118C_PE2H4 | rna-NM_001182956.1_PE2H4 | cds-NP_014281.1_PE2H4 | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:402652-405564:- | gene-YNL118C_S288C | rna-NM_001182956.1_S288C | cds-NP_014281.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:7965-10874:+ | gene-YNL118C_SA1 | rna-NM_001182956.1_SA1 | cds-NP_014281.1_SA1 | 99.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:390080-392992:- | gene-YNL118C_ThermosaccDry | rna-NM_001182956.1_ThermosaccDry | cds-NP_014281.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:408746-411655:- | gene-YNL118C_VR1 | rna-NM_001182956.1_VR1 | cds-NP_014281.1_VR1 | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:299913-302825:- | gene-YNL118C_ZTW1 | rna-NM_001182956.1_ZTW1 | cds-NP_014281.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:400898-403840:- | gene-YNL118C_Sparadoxus | rna-NM_001182956.1_Sparadoxus | cds-NP_014281.1_Sparadoxus | 85.9 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |