DCN1 (YLR128W)


Gene profile

Gene name: DCN1
Reference locus (S288C): YLR128W
Gene biotype: protein_coding

Description: Scaffold-type E3 ligase; required for cullin neddylation and ubiquitin ligase activation; contains a ubiquitin-binding domain (UBA) for ubiquitin and Nedd8 (Rub1p) interaction and a PONY domain involved in cullin binding and neddylation

Top 10 interactors (score): CDC53 (0.999); UBC12 (0.999); HRT1 (0.999); CUL3 (0.997); UBA3 (0.991); RRI1 (0.969); LAG2 (0.937); RUB1 (0.929); RTT101 (0.914); SKP1 (0.874); L9233.4 (0.844); CDC34 (0.828); ULA1 (0.792); RPC37 (0.761); ELC1 (0.759); TFB3 (0.721); YLR125W (0.691); SDA1 (0.66); TAO3 (0.646); HRT3 (0.626)

Homologues (species, bitscore): DCUN1D1 (Homo sapiens, 91.3); Dcun1d2 (Mus musculus, 87.4); dcun1d1 (Danio rerio, 98.2); dcun1d1 (Xenopus tropicalis, 91.7); CG7427 (Drosophila melanogaster, 87.0); dcn-1 (Caenorhabditis elegans, 69.3); AT3G12760 (Arabidopsis thaliana, 92.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:381011-381914:+ gene-YLR128W_AKU4011 rna-NM_001182015.1_AKU4011 cds-NP_013229.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:344795-345698:+ gene-YLR128W_BG1 rna-NM_001182015.1_BG1 cds-NP_013229.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:392890-393793:+ gene-YLR128W_Bruggeman rna-NM_001182015.1_Bruggeman cds-NP_013229.1_Bruggeman 99.0 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:392305-393208:+ gene-YLR128W_CAT1 rna-NM_001182015.1_CAT1 cds-NP_013229.1_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:388155-389058:+ gene-YLR128W_CBS1585 rna-NM_001182015.1_CBS1585 cds-NP_013229.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:378395-379298:+ gene-YLR128W_CBS436 rna-NM_001182015.1_CBS436 cds-NP_013229.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:386572-387475:+ gene-YLR128W_CBS6412 rna-NM_001182015.1_CBS6412 cds-NP_013229.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:388420-389323:+ gene-YLR128W_CBS6413 rna-NM_001182015.1_CBS6413 cds-NP_013229.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:383552-384455:+ gene-YLR128W_CENPK1137D rna-NM_001182015.1_CENPK1137D cds-NP_013229.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:381212-382115:+ gene-YLR128W_EthanolRed rna-NM_001182015.1_EthanolRed cds-NP_013229.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:380723-381626:+ gene-YLR128W_FaliES1 rna-NM_001182015.1_FaliES1 cds-NP_013229.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000117.1:11563-12466:- gene-YLR128W_JAY291 rna-NM_001182015.1_JAY291 cds-NP_013229.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:392881-393784:+ gene-YLR128W_MUCL30387 rna-NM_001182015.1_MUCL30387 cds-NP_013229.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:397700-398603:+ gene-YLR128W_MUCL30388 rna-NM_001182015.1_MUCL30388 cds-NP_013229.1_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:388664-389567:+ gene-YLR128W_MUCL39482 rna-NM_001182015.1_MUCL39482 cds-NP_013229.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:388789-389692:+ gene-YLR128W_MUCL42920 rna-NM_001182015.1_MUCL42920 cds-NP_013229.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:398504-399407:+ gene-YLR128W_NCIM3186 rna-NM_001182015.1_NCIM3186 cds-NP_013229.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:380936-381839:+ gene-YLR128W_NCYC1407 rna-NM_001182015.1_NCYC1407 cds-NP_013229.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:386505-387408:+ gene-YLR128W_PE2H3 rna-NM_001182015.1_PE2H3 cds-NP_013229.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:386246-387149:+ gene-YLR128W_PE2H4 rna-NM_001182015.1_PE2H4 cds-NP_013229.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:398530-399433:+ gene-YLR128W_S288C rna-NM_001182015.1_S288C cds-NP_013229.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000055.1:24443-25346:+ gene-YLR128W_SA1 rna-NM_001182015.1_SA1 cds-NP_013229.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:381933-382836:+ gene-YLR128W_ThermosaccDry rna-NM_001182015.1_ThermosaccDry cds-NP_013229.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:394647-395550:+ gene-YLR128W_VR1 rna-NM_001182015.1_VR1 cds-NP_013229.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:379730-380633:+ gene-YLR128W_ZTW1 rna-NM_001182015.1_ZTW1 cds-NP_013229.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:389814-390719:+ gene-YLR128W_Sparadoxus rna-NM_001182015.1_Sparadoxus cds-NP_013229.1_Sparadoxus 87.7 99.6 Verified 1 1 1 False True False False False

Additional files