DBP5 (YOR046C)


Gene profile

Gene name: DBP5
Reference locus (S288C): YOR046C
Gene biotype: protein_coding

Description: Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family; involved in mRNA export from the nucleus, remodeling messenger ribonucleoprotein particles (mRNPs), with ATPase activity stimulated by Gle1p, IP6 and Nup159p; involved in translation termination along with Sup45p (eRF1); role in the cellular response to heat stress

Top 10 interactors (score): MEX67 (0.999); GLE1 (0.999); NUP159 (0.999); NUP42 (0.998); CRM1 (0.992); NUP2 (0.977); NUP116 (0.977); GFD1 (0.966); RPL25 (0.945); NAB2 (0.945); NMD3 (0.944); HAS1 (0.942); NUP82 (0.942); DBP6 (0.941); DRS1 (0.938); DBP3 (0.938); YRA1 (0.937); MRT4 (0.933); RPL35B (0.931); LOC1 (0.929)

Homologues (species, bitscore): DDX19A (Homo sapiens, 444.9); Ddx19a (Mus musculus, 447.6); ddx19 (Danio rerio, 437.6); ddx19b (Xenopus tropicalis, 407.9); Dbp80 (Drosophila melanogaster, 361.7); ddx-19 (Caenorhabditis elegans, 323.6); LOS4 (Arabidopsis thaliana, 315.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:398800-400248:- gene-YOR046C_AKU4011 rna-NM_001183465.1_AKU4011 cds-NP_014689.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:214398-215846:- gene-YOR046C_BG1 rna-NM_001183465.1_BG1 cds-NP_014689.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:401538-402986:- gene-YOR046C_Bruggeman rna-NM_001183465.1_Bruggeman cds-NP_014689.1_Bruggeman 98.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:399718-401166:- gene-YOR046C_CAT1 rna-NM_001183465.1_CAT1 cds-NP_014689.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:393491-394939:- gene-YOR046C_CBS1585 rna-NM_001183465.1_CBS1585 cds-NP_014689.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:397863-399311:- gene-YOR046C_CBS436 rna-NM_001183465.1_CBS436 cds-NP_014689.1_CBS436 98.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:392845-394293:- gene-YOR046C_CBS6412 rna-NM_001183465.1_CBS6412 cds-NP_014689.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:400221-401669:- gene-YOR046C_CBS6413 rna-NM_001183465.1_CBS6413 cds-NP_014689.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:414457-415905:- gene-YOR046C_CENPK1137D rna-NM_001183465.1_CENPK1137D cds-NP_014689.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:395498-396946:- gene-YOR046C_EthanolRed rna-NM_001183465.1_EthanolRed cds-NP_014689.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:398845-400293:- gene-YOR046C_FaliES1 rna-NM_001183465.1_FaliES1 cds-NP_014689.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000035.1:69515-70962:- gene-YOR046C_JAY291 rna-NM_001183465.1_JAY291 cds-NP_014689.1_JAY291 99.9 99.9 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:406329-407777:- gene-YOR046C_MUCL30387 rna-NM_001183465.1_MUCL30387 cds-NP_014689.1_MUCL30387 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:409632-411080:- gene-YOR046C_MUCL30388 rna-NM_001183465.1_MUCL30388 cds-NP_014689.1_MUCL30388 98.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:400974-402422:- gene-YOR046C_MUCL39482 rna-NM_001183465.1_MUCL39482 cds-NP_014689.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:415810-417258:- gene-YOR046C_MUCL42920 rna-NM_001183465.1_MUCL42920 cds-NP_014689.1_MUCL42920 98.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:414348-415796:- gene-YOR046C_NCIM3186 rna-NM_001183465.1_NCIM3186 cds-NP_014689.1_NCIM3186 98.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:407676-409124:- gene-YOR046C_NCYC1407 rna-NM_001183465.1_NCYC1407 cds-NP_014689.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:406534-407982:- gene-YOR046C_PE2H3 rna-NM_001183465.1_PE2H3 cds-NP_014689.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:416915-418363:- gene-YOR046C_PE2H4 rna-NM_001183465.1_PE2H4 cds-NP_014689.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:414459-415907:- gene-YOR046C_S288C rna-NM_001183465.1_S288C cds-NP_014689.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:382401-383849:- gene-YOR046C_SA1 rna-NM_001183465.1_SA1 cds-NP_014689.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:397385-398833:- gene-YOR046C_ThermosaccDry rna-NM_001183465.1_ThermosaccDry cds-NP_014689.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:398293-399734:- gene-YOR046C_VR1 rna-NM_001183465.1_VR1 cds-NP_014689.1_VR1 94.7 98.0 Verified 1 1 0 False False True False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:132030-133478:- gene-YOR046C_ZTW1 rna-NM_001183465.1_ZTW1 cds-NP_014689.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:404836-406290:- gene-YOR046C_Sparadoxus rna-NM_001183465.1_Sparadoxus cds-NP_014689.1_Sparadoxus 91.0 99.7 Verified 1 1 1 False True False False False

Additional files