DBP2 (YNL112W)


Gene profile

Gene name: DBP2
Reference locus (S288C): YNL112W
Gene biotype: protein_coding

Description: ATP-dependent RNA helicase of the DEAD-box protein family; has strong preference for dsRNA; interacts with YRA1; required for assembly of Yra1p, Nab2p and Mex67p onto mRNA and formation of nuclear mRNP; involved in mRNA decay and rRNA processing; may be involved in suppression of transcription from cryptic initiation sites

Top 10 interactors (score): PRP43 (0.999); RNT1 (0.999); SDA1 (0.993); DRS1 (0.992); NOP7 (0.992); DHR2 (0.991); NSR1 (0.99); KRE33 (0.982); HAS1 (0.982); BMS1 (0.981); HCA4 (0.981); NOP1 (0.98); SPB1 (0.976); MAK5 (0.974); NOP58 (0.972); HMT1 (0.971); NOG2 (0.971); NUG1 (0.969); NOG1 (0.968); MTR4 (0.966)

Homologues (species, bitscore): DDX5 (Homo sapiens, 589.0); Ddx5 (Mus musculus, 588.6); ddx5 (Danio rerio, 594.0); ddx5 (Xenopus tropicalis, 589.7); CG10077 (Drosophila melanogaster, 577.0); F58E10.3 (Caenorhabditis elegans, 516.2); RH20 (Arabidopsis thaliana, 593.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:407305-409922:+ gene-YNL112W_AKU4011 rna-NM_001182950.3_AKU4011 cds-NP_014287.3_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:311304-313931:+ gene-YNL112W_BG1 rna-NM_001182950.3_BG1 cds-NP_014287.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:418032-420653:+ gene-YNL112W_Bruggeman rna-NM_001182950.3_Bruggeman cds-NP_014287.3_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:461078-463694:+ gene-YNL112W_CAT1 rna-NM_001182950.3_CAT1 cds-NP_014287.3_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:407911-410537:+ gene-YNL112W_CBS1585 rna-NM_001182950.3_CBS1585 cds-NP_014287.3_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:476336-478965:+ gene-YNL112W_CBS436 rna-NM_001182950.3_CBS436 cds-NP_014287.3_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:403395-406010:+ gene-YNL112W_CBS6412 rna-NM_001182950.3_CBS6412 cds-NP_014287.3_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:404397-407013:+ gene-YNL112W_CBS6413 rna-NM_001182950.3_CBS6413 cds-NP_014287.3_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:407485-410133:+ gene-YNL112W_CENPK1137D rna-NM_001182950.3_CENPK1137D cds-NP_014287.3_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:404308-406942:+ gene-YNL112W_EthanolRed rna-NM_001182950.3_EthanolRed cds-NP_014287.3_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:400204-402838:+ gene-YNL112W_FaliES1 rna-NM_001182950.3_FaliES1 cds-NP_014287.3_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000021.1:56591-59220:+ gene-YNL112W_JAY291 rna-NM_001182950.3_JAY291 cds-NP_014287.3_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:414199-416823:+ gene-YNL112W_MUCL30387 rna-NM_001182950.3_MUCL30387 cds-NP_014287.3_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:449363-451966:+ gene-YNL112W_MUCL30388 rna-NM_001182950.3_MUCL30388 cds-NP_014287.3_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:405215-407930:+ gene-YNL112W_MUCL39482 rna-NM_001182950.3_MUCL39482 cds-NP_014287.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:409331-411965:+ gene-YNL112W_MUCL42920 rna-NM_001182950.3_MUCL42920 cds-NP_014287.3_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:413608-416250:+ gene-YNL112W_NCIM3186 rna-NM_001182950.3_NCIM3186 cds-NP_014287.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:407358-410067:+ gene-YNL112W_NCYC1407 rna-NM_001182950.3_NCYC1407 cds-NP_014287.3_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:406340-408991:+ gene-YNL112W_PE2H3 rna-NM_001182950.3_PE2H3 cds-NP_014287.3_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:405746-408397:+ gene-YNL112W_PE2H4 rna-NM_001182950.3_PE2H4 cds-NP_014287.3_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:413639-416281:+ gene-YNL112W_S288C rna-NM_001182950.3_S288C cds-NP_014287.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000113.1:223-1495:+ gene-YNL112W_SA1 rna-NM_001182950.3_SA1 cds-NP_014287.3_SA1 77.1 77.5 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:401076-403710:+ gene-YNL112W_ThermosaccDry rna-NM_001182950.3_ThermosaccDry cds-NP_014287.3_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:419717-422409:+ gene-YNL112W_VR1 rna-NM_001182950.3_VR1 cds-NP_014287.3_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:310895-313528:+ gene-YNL112W_ZTW1 rna-NM_001182950.3_ZTW1 cds-NP_014287.3_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:411953-414597:+ gene-YNL112W_Sparadoxus rna-NM_001182950.3_Sparadoxus cds-NP_014287.3_Sparadoxus 94.2 100.0 Verified 1 1 1 False True False False False

Additional files