Gene name: DBF2
Reference locus (S288C): YGR092W
Gene biotype: protein_coding
Description: Cell cycle protein kinase DBF2; Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication
Top 10 interactors (score): MOB1 (0.999); CDC14 (0.998); TEM1 (0.992); CDC15 (0.985); MOB2 (0.98); CLB2 (0.968); NET1 (0.966); DBF20 (0.959); BUB2 (0.957); SPO12 (0.955); LTE1 (0.952); HOF1 (0.952); BFA1 (0.927); SIC1 (0.927); IQG1 (0.907); TAO3 (0.898); CDC5 (0.891); CHS2 (0.885); NUD1 (0.881); CCR4 (0.845)
Homologues (species, bitscore): STK38L (Homo sapiens, 253.8); Stk38l (Mus musculus, 251.9); stk38l (Danio rerio, 250.8); stk38l (Xenopus tropicalis, 251.9); wts (Drosophila melanogaster, 256.9); sax-1 (Caenorhabditis elegans, 243.4); AT5G09890 (Arabidopsis thaliana, 238.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:652371-654089:+ | gene-YGR092W_AKU4011 | rna-NM_001181221.3_AKU4011 | cds-NP_011606.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:88176-89894:+ | gene-YGR092W_BG1 | rna-NM_001181221.3_BG1 | cds-NP_011606.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:654559-656277:+ | gene-YGR092W_Bruggeman | rna-NM_001181221.3_Bruggeman | cds-NP_011606.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:652749-654467:+ | gene-YGR092W_CAT1 | rna-NM_001181221.3_CAT1 | cds-NP_011606.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:653335-655053:+ | gene-YGR092W_CBS1585 | rna-NM_001181221.3_CBS1585 | cds-NP_011606.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:654993-656711:+ | gene-YGR092W_CBS436 | rna-NM_001181221.3_CBS436 | cds-NP_011606.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:645028-646746:+ | gene-YGR092W_CBS6412 | rna-NM_001181221.3_CBS6412 | cds-NP_011606.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:649970-651688:+ | gene-YGR092W_CBS6413 | rna-NM_001181221.3_CBS6413 | cds-NP_011606.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:667864-669582:+ | gene-YGR092W_CENPK1137D | rna-NM_001181221.3_CENPK1137D | cds-NP_011606.3_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:639922-641640:+ | gene-YGR092W_EthanolRed | rna-NM_001181221.3_EthanolRed | cds-NP_011606.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:643767-645485:+ | gene-YGR092W_FaliES1 | rna-NM_001181221.3_FaliES1 | cds-NP_011606.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000396.1:31071-32789:- | gene-YGR092W_JAY291 | rna-NM_001181221.3_JAY291 | cds-NP_011606.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:651547-653265:+ | gene-YGR092W_MUCL30387 | rna-NM_001181221.3_MUCL30387 | cds-NP_011606.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:654359-656077:+ | gene-YGR092W_MUCL30388 | rna-NM_001181221.3_MUCL30388 | cds-NP_011606.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:649063-650781:+ | gene-YGR092W_MUCL39482 | rna-NM_001181221.3_MUCL39482 | cds-NP_011606.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:659371-661089:+ | gene-YGR092W_MUCL42920 | rna-NM_001181221.3_MUCL42920 | cds-NP_011606.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:668189-669907:+ | gene-YGR092W_NCIM3186 | rna-NM_001181221.3_NCIM3186 | cds-NP_011606.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:643752-645470:+ | gene-YGR092W_NCYC1407 | rna-NM_001181221.3_NCYC1407 | cds-NP_011606.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:646439-648157:+ | gene-YGR092W_PE2H3 | rna-NM_001181221.3_PE2H3 | cds-NP_011606.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:651559-653277:+ | gene-YGR092W_PE2H4 | rna-NM_001181221.3_PE2H4 | cds-NP_011606.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:668189-669907:+ | gene-YGR092W_S288C | rna-NM_001181221.3_S288C | cds-NP_011606.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:94763-96481:+ | gene-YGR092W_SA1 | rna-NM_001181221.3_SA1 | cds-NP_011606.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:664137-665855:+ | gene-YGR092W_ThermosaccDry | rna-NM_001181221.3_ThermosaccDry | cds-NP_011606.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:760629-762347:+ | gene-YGR092W_VR1 | rna-NM_001181221.3_VR1 | cds-NP_011606.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:118387-120105:+ | gene-YGR092W_ZTW1 | rna-NM_001181221.3_ZTW1 | cds-NP_011606.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:654151-655872:+ | gene-YGR092W_Sparadoxus | rna-NM_001181221.3_Sparadoxus | cds-NP_011606.3_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |