DAD2 (YKR083C)


Gene profile

Gene name: DAD2
Reference locus (S288C): YKR083C
Gene biotype: protein_coding

Description: Essential subunit of the Dam1 complex (aka DASH complex); complex couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis

Top 10 interactors (score): ASK1 (0.999); DAD1 (0.998); SPC34 (0.998); SPC19 (0.998); DAD4 (0.998); DUO1 (0.998); HSK3 (0.993); DAD3 (0.993); DAM1 (0.992); CHL4 (0.925); CDC7 (0.907); IML3 (0.903); DSN1 (0.854); DBF4 (0.85); NNF1 (0.745); NUF2 (0.706); MTW1 (0.594); SPC24 (0.584); CTF3 (0.571); YKR015C (0.53)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:582451-582852:- gene-YKR083C_AKU4011 rna-NM_001179873.1_AKU4011 cds-NP_013009.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:61373-61774:+ gene-YKR083C_BG1 rna-NM_001179873.1_BG1 cds-NP_013009.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:605029-605430:- gene-YKR083C_Bruggeman rna-NM_001179873.1_Bruggeman cds-NP_013009.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:600950-601351:- gene-YKR083C_CAT1 rna-NM_001179873.1_CAT1 cds-NP_013009.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:594938-595339:- gene-YKR083C_CBS1585 rna-NM_001179873.1_CBS1585 cds-NP_013009.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:593323-593724:- gene-YKR083C_CBS436 rna-NM_001179873.1_CBS436 cds-NP_013009.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:578226-578627:- gene-YKR083C_CBS6412 rna-NM_001179873.1_CBS6412 cds-NP_013009.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:594756-595157:- gene-YKR083C_CBS6413 rna-NM_001179873.1_CBS6413 cds-NP_013009.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:596076-596477:- gene-YKR083C_CENPK1137D rna-NM_001179873.1_CENPK1137D cds-NP_013009.1_CENPK1137D 99.5 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:592263-592664:- gene-YKR083C_EthanolRed rna-NM_001179873.1_EthanolRed cds-NP_013009.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:596158-596559:- gene-YKR083C_FaliES1 rna-NM_001179873.1_FaliES1 cds-NP_013009.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000426.1:48375-48776:+ gene-YKR083C_JAY291 rna-NM_001179873.1_JAY291 cds-NP_013009.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:604525-604926:- gene-YKR083C_MUCL30387 rna-NM_001179873.1_MUCL30387 cds-NP_013009.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:598868-599269:- gene-YKR083C_MUCL30388 rna-NM_001179873.1_MUCL30388 cds-NP_013009.1_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:593779-594180:- gene-YKR083C_MUCL39482 rna-NM_001179873.1_MUCL39482 cds-NP_013009.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:599802-600203:- gene-YKR083C_MUCL42920 rna-NM_001179873.1_MUCL42920 cds-NP_013009.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:596410-596811:- gene-YKR083C_NCIM3186 rna-NM_001179873.1_NCIM3186 cds-NP_013009.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:594191-594592:- gene-YKR083C_NCYC1407 rna-NM_001179873.1_NCYC1407 cds-NP_013009.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:619396-619797:- gene-YKR083C_PE2H3 rna-NM_001179873.1_PE2H3 cds-NP_013009.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:603800-604201:- gene-YKR083C_PE2H4 rna-NM_001179873.1_PE2H4 cds-NP_013009.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:596421-596822:- gene-YKR083C_S288C rna-NM_001179873.1_S288C cds-NP_013009.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000029.1:85027-85428:+ gene-YKR083C_SA1 rna-NM_001179873.1_SA1 cds-NP_013009.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:595405-595806:- gene-YKR083C_ThermosaccDry rna-NM_001179873.1_ThermosaccDry cds-NP_013009.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:594667-595068:- gene-YKR083C_VR1 rna-NM_001179873.1_VR1 cds-NP_013009.1_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:592386-592787:- gene-YKR083C_ZTW1 rna-NM_001179873.1_ZTW1 cds-NP_013009.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:617631-618032:- gene-YKR083C_Sparadoxus rna-NM_001179873.1_Sparadoxus cds-NP_013009.1_Sparadoxus 89.8 100.0 Verified 1 1 1 False True False False False

Additional files