CYT2 (YKL087C)


Gene profile

Gene name: CYT2
Reference locus (S288C): YKL087C
Gene biotype: protein_coding

Description: Cytochrome c1 heme lyase; involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1; human homolog HCCS can complement yeast cyt2 null mutant

Top 10 interactors (score): COX10 (0.975); CYT1 (0.954); TIM23 (0.928); HEM15 (0.901); CYC3 (0.852); CYC1 (0.851); CYC7 (0.84); CYC2 (0.817); BCS1 (0.785); CBP3 (0.736); CBP4 (0.735); PUF3 (0.733); COX20 (0.725); COX17 (0.711); PET123 (0.68); RSM10 (0.647); TIM8 (0.643); MRPL20 (0.613); PET117 (0.604); CBP2 (0.597)

Homologues (species, bitscore): HCCS (Homo sapiens, 128.3); Hccs (Mus musculus, 129.8); hccsa (Danio rerio, 130.2); hccs (Xenopus tropicalis, 134.4); Cchl (Drosophila melanogaster, 120.6); cchl-1 (Caenorhabditis elegans, 131.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:263745-264419:- gene-YKL087C_AKU4011 rna-NM_001179653.1_AKU4011 cds-NP_012836.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:240923-241597:- gene-YKL087C_BG1 rna-NM_001179653.1_BG1 cds-NP_012836.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:281919-282593:- gene-YKL087C_Bruggeman rna-NM_001179653.1_Bruggeman cds-NP_012836.1_Bruggeman 99.1 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:276721-277395:- gene-YKL087C_CAT1 rna-NM_001179653.1_CAT1 cds-NP_012836.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:275987-276661:- gene-YKL087C_CBS1585 rna-NM_001179653.1_CBS1585 cds-NP_012836.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:274583-275257:- gene-YKL087C_CBS436 rna-NM_001179653.1_CBS436 cds-NP_012836.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:260615-261289:- gene-YKL087C_CBS6412 rna-NM_001179653.1_CBS6412 cds-NP_012836.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:276443-277117:- gene-YKL087C_CBS6413 rna-NM_001179653.1_CBS6413 cds-NP_012836.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:276826-277507:- gene-YKL087C_CENPK1137D rna-NM_001179653.1_CENPK1137D cds-NP_012836.1_CENPK1137D 98.9 100.0 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:274439-275113:- gene-YKL087C_EthanolRed rna-NM_001179653.1_EthanolRed cds-NP_012836.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:275252-275926:- gene-YKL087C_FaliES1 rna-NM_001179653.1_FaliES1 cds-NP_012836.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:97585-98259:- gene-YKL087C_JAY291 rna-NM_001179653.1_JAY291 cds-NP_012836.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:283717-284391:- gene-YKL087C_MUCL30387 rna-NM_001179653.1_MUCL30387 cds-NP_012836.1_MUCL30387 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:278113-278787:- gene-YKL087C_MUCL30388 rna-NM_001179653.1_MUCL30388 cds-NP_012836.1_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:275772-276446:- gene-YKL087C_MUCL39482 rna-NM_001179653.1_MUCL39482 cds-NP_012836.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:280409-281083:- gene-YKL087C_MUCL42920 rna-NM_001179653.1_MUCL42920 cds-NP_012836.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:277178-277852:- gene-YKL087C_NCIM3186 rna-NM_001179653.1_NCIM3186 cds-NP_012836.1_NCIM3186 98.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:275966-276640:- gene-YKL087C_NCYC1407 rna-NM_001179653.1_NCYC1407 cds-NP_012836.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:283058-283732:- gene-YKL087C_PE2H3 rna-NM_001179653.1_PE2H3 cds-NP_012836.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:279345-280019:- gene-YKL087C_PE2H4 rna-NM_001179653.1_PE2H4 cds-NP_012836.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:277189-277863:- gene-YKL087C_S288C rna-NM_001179653.1_S288C cds-NP_012836.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:193319-193993:- gene-YKL087C_SA1 rna-NM_001179653.1_SA1 cds-NP_012836.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:275957-276631:- gene-YKL087C_ThermosaccDry rna-NM_001179653.1_ThermosaccDry cds-NP_012836.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:275318-275992:- gene-YKL087C_VR1 rna-NM_001179653.1_VR1 cds-NP_012836.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:274524-275198:- gene-YKL087C_ZTW1 rna-NM_001179653.1_ZTW1 cds-NP_012836.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:291635-292309:- gene-YKL087C_Sparadoxus rna-NM_001179653.1_Sparadoxus cds-NP_012836.1_Sparadoxus 90.6 99.7 Verified 1 1 1 False True False False False

Additional files