Gene name: CYS3
Reference locus (S288C): YAL012W
Gene biotype: protein_coding
Description: Cystathionine gamma-lyase; catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine; protein abundance increases in response to DNA replication stress; Belongs to the trans-sulfuration enzymes family
Top 10 interactors (score): CYS4 (0.999); GSH1 (0.986); MCY1 (0.98); MET6 (0.976); AAT2 (0.969); SAH1 (0.967); TUM1 (0.963); STR2 (0.946); SAM1 (0.946); YLL058W (0.942); BAT2 (0.941); AAT1 (0.939); YML082W (0.931); MET17 (0.93); IRC7 (0.929); TRR1 (0.928); STR3 (0.927); HOM6 (0.921); MES1 (0.92); BAT1 (0.919)
Homologues (species, bitscore): CTH (Homo sapiens, 385.2); Cth (Mus musculus, 370.5); cth (Danio rerio, 389.8); cth (Xenopus tropicalis, 399.1); Eip55E (Drosophila melanogaster, 365.9); cth-2 (Caenorhabditis elegans, 362.5); CBL (Arabidopsis thaliana, 281.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:115911-117095:+ | gene-YAL012W_AKU4011 | rna-NM_001178157.1_AKU4011 | cds-NP_009390.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:102861-104045:+ | gene-YAL012W_BG1 | rna-NM_001178157.1_BG1 | cds-NP_009390.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:130784-131968:+ | gene-YAL012W_Bruggeman | rna-NM_001178157.1_Bruggeman | cds-NP_009390.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:117120-118304:+ | gene-YAL012W_CAT1 | rna-NM_001178157.1_CAT1 | cds-NP_009390.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:128923-130107:+ | gene-YAL012W_CBS1585 | rna-NM_001178157.1_CBS1585 | cds-NP_009390.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:129201-130385:+ | gene-YAL012W_CBS436 | rna-NM_001178157.1_CBS436 | cds-NP_009390.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:742017-743201:+ | gene-YAL012W_CBS6412 | rna-NM_001178157.1_CBS6412 | cds-NP_009390.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:127193-128377:+ | gene-YAL012W_CBS6413 | rna-NM_001178157.1_CBS6413 | cds-NP_009390.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:130959-132143:+ | gene-YAL012W_CENPK1137D | rna-NM_001178157.1_CENPK1137D | cds-NP_009390.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:117330-118514:+ | gene-YAL012W_EthanolRed | rna-NM_001178157.1_EthanolRed | cds-NP_009390.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:131957-133141:+ | gene-YAL012W_FaliES1 | rna-NM_001178157.1_FaliES1 | cds-NP_009390.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:103228-104412:+ | gene-YAL012W_JAY291 | rna-NM_001178157.1_JAY291 | cds-NP_009390.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:131937-133121:+ | gene-YAL012W_MUCL30387 | rna-NM_001178157.1_MUCL30387 | cds-NP_009390.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:129184-130368:+ | gene-YAL012W_MUCL30388 | rna-NM_001178157.1_MUCL30388 | cds-NP_009390.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:127705-128889:+ | gene-YAL012W_MUCL39482 | rna-NM_001178157.1_MUCL39482 | cds-NP_009390.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:130086-131270:+ | gene-YAL012W_MUCL42920 | rna-NM_001178157.1_MUCL42920 | cds-NP_009390.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:130676-131860:+ | gene-YAL012W_NCIM3186 | rna-NM_001178157.1_NCIM3186 | cds-NP_009390.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:115588-116772:+ | gene-YAL012W_NCYC1407 | rna-NM_001178157.1_NCYC1407 | cds-NP_009390.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:117516-118700:+ | gene-YAL012W_PE2H3 | rna-NM_001178157.1_PE2H3 | cds-NP_009390.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:117235-118419:+ | gene-YAL012W_PE2H4 | rna-NM_001178157.1_PE2H4 | cds-NP_009390.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:130799-131983:+ | gene-YAL012W_S288C | rna-NM_001178157.1_S288C | cds-NP_009390.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000077.1:47720-48904:+ | gene-YAL012W_SA1 | rna-NM_001178157.1_SA1 | cds-NP_009390.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:131449-132633:+ | gene-YAL012W_ThermosaccDry | rna-NM_001178157.1_ThermosaccDry | cds-NP_009390.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:132759-133943:+ | gene-YAL012W_VR1 | rna-NM_001178157.1_VR1 | cds-NP_009390.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:103277-104461:+ | gene-YAL012W_ZTW1 | rna-NM_001178157.1_ZTW1 | cds-NP_009390.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:120750-121934:+ | gene-YAL012W_Sparadoxus | rna-NM_001178157.1_Sparadoxus | cds-NP_009390.1_Sparadoxus | 94.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |