CYR1 (YJL005W)


Gene profile

Gene name: CYR1
Reference locus (S288C): YJL005W
Gene biotype: protein_coding

Description: Adenylate cyclase; required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation

Top 10 interactors (score): SRV2 (0.999); RAS1 (0.999); BCY1 (0.999); GPA2 (0.999); TPK1 (0.999); RAS2 (0.999); PDE2 (0.998); TPK2 (0.998); TPK3 (0.997); PDE1 (0.996); ACT1 (0.996); GPR1 (0.994); SGT1 (0.99); GPA1 (0.989); CDC25 (0.985); SCH9 (0.962); STE4 (0.959); IRA1 (0.947); HSC82 (0.947); IRA2 (0.945)

Homologues (species, bitscore): PHLPP1 (Homo sapiens, 166.0); Phlpp1 (Mus musculus, 166.8); PHLPP1 (Danio rerio, 141.4); phlpp2 (Xenopus tropicalis, 202.2); scrib (Drosophila melanogaster, 124.0); F43C1.1 (Caenorhabditis elegans, 141.0); PIRL5 (Arabidopsis thaliana, 104.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:408301-414405:+ gene-YJL005W_AKU4011 rna-NM_001181439.3_AKU4011 cds-NP_012529.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:198320-204424:- gene-YJL005W_BG1 rna-NM_001181439.3_BG1 cds-NP_012529.3_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:422393-428497:+ gene-YJL005W_Bruggeman rna-NM_001181439.3_Bruggeman cds-NP_012529.3_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:426342-432446:+ gene-YJL005W_CAT1 rna-NM_001181439.3_CAT1 cds-NP_012529.3_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:419881-425985:+ gene-YJL005W_CBS1585 rna-NM_001181439.3_CBS1585 cds-NP_012529.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:438867-444971:+ gene-YJL005W_CBS436 rna-NM_001181439.3_CBS436 cds-NP_012529.3_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:408115-414219:+ gene-YJL005W_CBS6412 rna-NM_001181439.3_CBS6412 cds-NP_012529.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:410336-416440:+ gene-YJL005W_CBS6413 rna-NM_001181439.3_CBS6413 cds-NP_012529.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:407646-413726:+ gene-YJL005W_CENPK1137D rna-NM_001181439.3_CENPK1137D cds-NP_012529.3_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:413269-419373:+ gene-YJL005W_EthanolRed rna-NM_001181439.3_EthanolRed cds-NP_012529.3_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:424409-430513:+ gene-YJL005W_FaliES1 rna-NM_001181439.3_FaliES1 cds-NP_012529.3_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000321.1:22719-28823:- gene-YJL005W_JAY291 rna-NM_001181439.3_JAY291 cds-NP_012529.3_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:422724-428828:+ gene-YJL005W_MUCL30387 rna-NM_001181439.3_MUCL30387 cds-NP_012529.3_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:419247-425351:+ gene-YJL005W_MUCL30388 rna-NM_001181439.3_MUCL30388 cds-NP_012529.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:413215-419319:+ gene-YJL005W_MUCL39482 rna-NM_001181439.3_MUCL39482 cds-NP_012529.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:418660-424764:+ gene-YJL005W_MUCL42920 rna-NM_001181439.3_MUCL42920 cds-NP_012529.3_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:425136-431216:+ gene-YJL005W_NCIM3186 rna-NM_001181439.3_NCIM3186 cds-NP_012529.3_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:411117-417221:+ gene-YJL005W_NCYC1407 rna-NM_001181439.3_NCYC1407 cds-NP_012529.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:429525-435629:+ gene-YJL005W_PE2H3 rna-NM_001181439.3_PE2H3 cds-NP_012529.3_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:423219-429323:+ gene-YJL005W_PE2H4 rna-NM_001181439.3_PE2H4 cds-NP_012529.3_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:425157-431237:+ gene-YJL005W_S288C rna-NM_001181439.3_S288C cds-NP_012529.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:221143-227247:+ gene-YJL005W_SA1 rna-NM_001181439.3_SA1 cds-NP_012529.3_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:418069-424173:+ gene-YJL005W_ThermosaccDry rna-NM_001181439.3_ThermosaccDry cds-NP_012529.3_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:420444-426548:+ gene-YJL005W_VR1 rna-NM_001181439.3_VR1 cds-NP_012529.3_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:398080-404184:+ gene-YJL005W_ZTW1 rna-NM_001181439.3_ZTW1 cds-NP_012529.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:422953-429063:+ gene-YJL005W_Sparadoxus rna-NM_001181439.3_Sparadoxus cds-NP_012529.3_Sparadoxus 90.3 100.0 Verified 1 1 1 False True False False False

Additional files