CYM1 (YDR430C)


Gene profile

Gene name: CYM1
Reference locus (S288C): YDR430C
Gene biotype: protein_coding

Description: Mitochondrial presequence protease; Lysine-specific metalloprotease of the pitrilysin family; metalloprotease of the intermembrane space; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology

Top 10 interactors (score): OCT1 (0.938); JAC1 (0.914); HSP60 (0.909); YFH1 (0.908); GCN1 (0.903); ARG3 (0.9); MCD1 (0.892); STE23 (0.881); PRD1 (0.827); PDX1 (0.822); MAS1 (0.808); LAT1 (0.805); PDA1 (0.783); LPD1 (0.764); PUF3 (0.763); PDB1 (0.76); MAS2 (0.736); MPM1 (0.658); HOT13 (0.647); VPS41 (0.639)

Homologues (species, bitscore): PITRM1 (Homo sapiens, 614.4); Pitrm1 (Mus musculus, 610.1); pitrm1 (Danio rerio, 594.7); pitrm1 (Xenopus tropicalis, 490.0); CG3107 (Drosophila melanogaster, 502.7); C05D11.1 (Caenorhabditis elegans, 85.5); PREP2 (Arabidopsis thaliana, 392.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1265769-1268738:- gene-YDR430C_AKU4011 rna-NM_001180738.1_AKU4011 cds-NP_010718.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:144108-147077:- gene-YDR430C_BG1 rna-NM_001180738.1_BG1 cds-NP_010718.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1296156-1299125:- gene-YDR430C_Bruggeman rna-NM_001180738.1_Bruggeman cds-NP_010718.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1274350-1277319:- gene-YDR430C_CAT1 rna-NM_001180738.1_CAT1 cds-NP_010718.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1260098-1263067:- gene-YDR430C_CBS1585 rna-NM_001180738.1_CBS1585 cds-NP_010718.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1279430-1282399:- gene-YDR430C_CBS436 rna-NM_001180738.1_CBS436 cds-NP_010718.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1256064-1259033:- gene-YDR430C_CBS6412 rna-NM_001180738.1_CBS6412 cds-NP_010718.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1278213-1281182:- gene-YDR430C_CBS6413 rna-NM_001180738.1_CBS6413 cds-NP_010718.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1324179-1327148:- gene-YDR430C_CENPK1137D rna-NM_001180738.1_CENPK1137D cds-NP_010718.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1269346-1272315:- gene-YDR430C_EthanolRed rna-NM_001180738.1_EthanolRed cds-NP_010718.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1272653-1275622:- gene-YDR430C_FaliES1 rna-NM_001180738.1_FaliES1 cds-NP_010718.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000263.1:16932-19900:- gene-YDR430C_JAY291 rna-NM_001180738.1_JAY291 cds-NP_010718.1_JAY291 99.6 99.9 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1279798-1282767:- gene-YDR430C_MUCL30387 rna-NM_001180738.1_MUCL30387 cds-NP_010718.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1261734-1264703:- gene-YDR430C_MUCL30388 rna-NM_001180738.1_MUCL30388 cds-NP_010718.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1251590-1254559:- gene-YDR430C_MUCL39482 rna-NM_001180738.1_MUCL39482 cds-NP_010718.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1193990-1196959:- gene-YDR430C_MUCL42920 rna-NM_001180738.1_MUCL42920 cds-NP_010718.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1325424-1328393:- gene-YDR430C_NCIM3186 rna-NM_001180738.1_NCIM3186 cds-NP_010718.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1265354-1268323:- gene-YDR430C_NCYC1407 rna-NM_001180738.1_NCYC1407 cds-NP_010718.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1276175-1279144:- gene-YDR430C_PE2H3 rna-NM_001180738.1_PE2H3 cds-NP_010718.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1281743-1284712:- gene-YDR430C_PE2H4 rna-NM_001180738.1_PE2H4 cds-NP_010718.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1325501-1328470:- gene-YDR430C_S288C rna-NM_001180738.1_S288C cds-NP_010718.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000082.1:28747-31716:+ gene-YDR430C_SA1 rna-NM_001180738.1_SA1 cds-NP_010718.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1276915-1279884:- gene-YDR430C_ThermosaccDry rna-NM_001180738.1_ThermosaccDry cds-NP_010718.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1292137-1295106:- gene-YDR430C_VR1 rna-NM_001180738.1_VR1 cds-NP_010718.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:319557-322526:- gene-YDR430C_ZTW1 rna-NM_001180738.1_ZTW1 cds-NP_010718.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1273310-1276279:- gene-YDR430C_Sparadoxus rna-NM_001180738.1_Sparadoxus cds-NP_010718.1_Sparadoxus 89.1 100.0 Verified 1 1 1 False True False False False

Additional files