Gene name: CYC8
Reference locus (S288C): YBR112C
Gene biotype: protein_coding
Description: General transcriptional co-repressor; acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters; can form the prion [OCT+]
Top 10 interactors (score): TUP1 (0.999); MIG1 (0.998); RGT1 (0.997); RTT107 (0.997); SKO1 (0.997); SWD1 (0.996); SWD3 (0.996); BRE2 (0.992); HHT2 (0.98); CTI6 (0.974); ROX1 (0.967); MCM1 (0.965); MOT3 (0.958); HTZ1 (0.953); RFX1 (0.952); RPD3 (0.945); HOG1 (0.939); SNF2 (0.93); SFL1 (0.923); SWI1 (0.922)
Homologues (species, bitscore): KDM6A (Homo sapiens, 185.3); Kdm6a (Mus musculus, 183.3); kdm6a (Danio rerio, 176.4); kdm6a (Xenopus tropicalis, 185.3); Utx (Drosophila melanogaster, 152.5); utx-1 (Caenorhabditis elegans, 106.3); SPY (Arabidopsis thaliana, 87.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:445266-448169:- | gene-YBR112C_AKU4011 | rna-NM_001178460.3_AKU4011 | cds-NP_009670.3_AKU4011 | 98.4 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:436311-439202:- | gene-YBR112C_BG1 | rna-NM_001178460.3_BG1 | cds-NP_009670.3_BG1 | 98.1 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:446996-449941:- | gene-YBR112C_Bruggeman | rna-NM_001178460.3_Bruggeman | cds-NP_009670.3_Bruggeman | 97.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:449789-452729:- | gene-YBR112C_CAT1 | rna-NM_001178460.3_CAT1 | cds-NP_009670.3_CAT1 | 88.5 | 95.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:437549-440452:- | gene-YBR112C_CBS1585 | rna-NM_001178460.3_CBS1585 | cds-NP_009670.3_CBS1585 | 98.4 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:445644-448520:- | gene-YBR112C_CBS436 | rna-NM_001178460.3_CBS436 | cds-NP_009670.3_CBS436 | 98.0 | 99.1 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:535778-538681:- | gene-YBR112C_CBS6412 | rna-NM_001178460.3_CBS6412 | cds-NP_009670.3_CBS6412 | 98.4 | 99.4 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:442690-445581:- | gene-YBR112C_CBS6413 | rna-NM_001178460.3_CBS6413 | cds-NP_009670.3_CBS6413 | 98.4 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:454768-457668:- | gene-YBR112C_CENPK1137D | rna-NM_001178460.3_CENPK1137D | cds-NP_009670.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:572022-574922:- | gene-YBR112C_EthanolRed | rna-NM_001178460.3_EthanolRed | cds-NP_009670.3_EthanolRed | 99.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:461305-464205:- | gene-YBR112C_FaliES1 | rna-NM_001178460.3_FaliES1 | cds-NP_009670.3_FaliES1 | 99.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000312.1:32238-35105:- | gene-YBR112C_JAY291 | rna-NM_001178460.3_JAY291 | cds-NP_009670.3_JAY291 | 98.4 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:449706-452594:- | gene-YBR112C_MUCL30387 | rna-NM_001178460.3_MUCL30387 | cds-NP_009670.3_MUCL30387 | 98.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:448050-451202:- | gene-YBR112C_MUCL30388 | rna-NM_001178460.3_MUCL30388 | cds-NP_009670.3_MUCL30388 | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:435692-438595:- | gene-YBR112C_MUCL39482 | rna-NM_001178460.3_MUCL39482 | cds-NP_009670.3_MUCL39482 | 98.4 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:445348-448251:- | gene-YBR112C_MUCL42920 | rna-NM_001178460.3_MUCL42920 | cds-NP_009670.3_MUCL42920 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:462667-465567:- | gene-YBR112C_NCIM3186 | rna-NM_001178460.3_NCIM3186 | cds-NP_009670.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:438473-441373:- | gene-YBR112C_NCYC1407 | rna-NM_001178460.3_NCYC1407 | cds-NP_009670.3_NCYC1407 | 98.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:451083-453950:- | gene-YBR112C_PE2H3 | rna-NM_001178460.3_PE2H3 | cds-NP_009670.3_PE2H3 | 98.4 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:448759-451626:- | gene-YBR112C_PE2H4 | rna-NM_001178460.3_PE2H4 | cds-NP_009670.3_PE2H4 | 98.4 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:462870-465770:- | gene-YBR112C_S288C | rna-NM_001178460.3_S288C | cds-NP_009670.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:12001-14835:+ | gene-YBR112C_SA1 | rna-NM_001178460.3_SA1 | cds-NP_009670.3_SA1 | 97.2 | 97.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:460312-463212:- | gene-YBR112C_ThermosaccDry | rna-NM_001178460.3_ThermosaccDry | cds-NP_009670.3_ThermosaccDry | 99.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:442345-445191:- | gene-YBR112C_VR1 | rna-NM_001178460.3_VR1 | cds-NP_009670.3_VR1 | 95.5 | 97.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:435985-438861:- | gene-YBR112C_ZTW1 | rna-NM_001178460.3_ZTW1 | cds-NP_009670.3_ZTW1 | 97.8 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:473069-476038:- | gene-YBR112C_Sparadoxus | rna-NM_001178460.3_Sparadoxus | cds-NP_009670.3_Sparadoxus | 86.8 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |