Gene name: CYC3
Reference locus (S288C): YAL039C
Gene biotype: protein_coding
Description: Cytochrome c heme lyase (holocytochrome c synthase); attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in mitochondrial intermembrane space; human homolog HCCS implicated in microphthalmia with linear skin defects (MLS), and can complement yeast null mutant
Top 10 interactors (score): CYC7 (0.978); CYC2 (0.972); COX10 (0.956); CYC1 (0.948); CTM1 (0.92); HEM15 (0.914); ILV1 (0.908); CYT1 (0.893); CYT2 (0.852); ERV1 (0.775); MIA40 (0.775); TIM23 (0.679); COX12 (0.677); PUF3 (0.672); COX15 (0.641); RPS20 (0.636); QCR8 (0.618); TIM8 (0.615); YAT1 (0.608); RSM10 (0.603)
Homologues (species, bitscore): HCCS (Homo sapiens, 133.7); Hccs (Mus musculus, 134.4); hccs (Danio rerio, 143.7); hccs (Xenopus tropicalis, 137.5); Cchl (Drosophila melanogaster, 156.4); cchl-1 (Caenorhabditis elegans, 136.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:53859-54668:- | gene-YAL039C_AKU4011 | rna-NM_001178184.1_AKU4011 | cds-NP_009361.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:40929-41738:- | gene-YAL039C_BG1 | rna-NM_001178184.1_BG1 | cds-NP_009361.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:68318-69127:- | gene-YAL039C_Bruggeman | rna-NM_001178184.1_Bruggeman | cds-NP_009361.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:55079-55888:- | gene-YAL039C_CAT1 | rna-NM_001178184.1_CAT1 | cds-NP_009361.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:66879-67688:- | gene-YAL039C_CBS1585 | rna-NM_001178184.1_CBS1585 | cds-NP_009361.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:67122-67931:- | gene-YAL039C_CBS436 | rna-NM_001178184.1_CBS436 | cds-NP_009361.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:53024-53833:- | gene-YAL039C_CBS6412 | rna-NM_001178184.1_CBS6412 | cds-NP_009361.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:65142-65951:- | gene-YAL039C_CBS6413 | rna-NM_001178184.1_CBS6413 | cds-NP_009361.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:68777-69586:- | gene-YAL039C_CENPK1137D | rna-NM_001178184.1_CENPK1137D | cds-NP_009361.1_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:55273-56082:- | gene-YAL039C_EthanolRed | rna-NM_001178184.1_EthanolRed | cds-NP_009361.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:69215-70024:- | gene-YAL039C_FaliES1 | rna-NM_001178184.1_FaliES1 | cds-NP_009361.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:41166-41975:- | gene-YAL039C_JAY291 | rna-NM_001178184.1_JAY291 | cds-NP_009361.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:69826-70635:- | gene-YAL039C_MUCL30387 | rna-NM_001178184.1_MUCL30387 | cds-NP_009361.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:66368-67177:- | gene-YAL039C_MUCL30388 | rna-NM_001178184.1_MUCL30388 | cds-NP_009361.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:65683-66492:- | gene-YAL039C_MUCL39482 | rna-NM_001178184.1_MUCL39482 | cds-NP_009361.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:68033-68842:- | gene-YAL039C_MUCL42920 | rna-NM_001178184.1_MUCL42920 | cds-NP_009361.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:68593-69402:- | gene-YAL039C_NCIM3186 | rna-NM_001178184.1_NCIM3186 | cds-NP_009361.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:53548-54357:- | gene-YAL039C_NCYC1407 | rna-NM_001178184.1_NCYC1407 | cds-NP_009361.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:55432-56241:- | gene-YAL039C_PE2H3 | rna-NM_001178184.1_PE2H3 | cds-NP_009361.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:55151-55960:- | gene-YAL039C_PE2H4 | rna-NM_001178184.1_PE2H4 | cds-NP_009361.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:68716-69525:- | gene-YAL039C_S288C | rna-NM_001178184.1_S288C | cds-NP_009361.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000084.1:43326-44135:- | gene-YAL039C_SA1 | rna-NM_001178184.1_SA1 | cds-NP_009361.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:69425-70234:- | gene-YAL039C_ThermosaccDry | rna-NM_001178184.1_ThermosaccDry | cds-NP_009361.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:70693-71502:- | gene-YAL039C_VR1 | rna-NM_001178184.1_VR1 | cds-NP_009361.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:41231-42040:- | gene-YAL039C_ZTW1 | rna-NM_001178184.1_ZTW1 | cds-NP_009361.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:58892-59704:- | gene-YAL039C_Sparadoxus | rna-NM_001178184.1_Sparadoxus | cds-NP_009361.1_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |