Gene name: CYC1
Reference locus (S288C): YJR048W
Gene biotype: protein_coding
Description: Cytochrome c, isoform 1; also known as iso-1-cytochrome c; electron carrier of mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration; CYC1 has a paralog, CYC7, that arose from the whole genome duplication; human homolog CYC1 can complement yeast null mutant; mutations in human CYC1 cause insulin-responsive hyperglycemia
Top 10 interactors (score): QCR7 (0.999); COR1 (0.999); RIP1 (0.999); QCR6 (0.999); QCR8 (0.999); CYT1 (0.999); QCR9 (0.999); CCP1 (0.995); COX4 (0.993); COB (0.992); QCR2 (0.989); COX5A (0.988); COX6 (0.977); COX12 (0.962); NDE1 (0.959); BI4 (0.951); COX13 (0.948); CYC3 (0.948); CYC7 (0.942); MAS1 (0.934)
Homologues (species, bitscore): CYCS (Homo sapiens, 141.4); Gm10053 (Mus musculus, 142.9); cycsb (Danio rerio, 141.4); cycs (Xenopus tropicalis, 148.3); Cyt-c-p (Drosophila melanogaster, 143.7); cyc-2.1 (Caenorhabditis elegans, 117.9); CYTC-1 (Arabidopsis thaliana, 134.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:498025-498354:+ | gene-YJR048W_AKU4011 | rna-NM_001181706.1_AKU4011 | cds-NP_012582.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:114636-114965:- | gene-YJR048W_BG1 | rna-NM_001181706.1_BG1 | cds-NP_012582.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:512074-512403:+ | gene-YJR048W_Bruggeman | rna-NM_001181706.1_Bruggeman | cds-NP_012582.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:516244-516573:+ | gene-YJR048W_CAT1 | rna-NM_001181706.1_CAT1 | cds-NP_012582.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:510095-510424:+ | gene-YJR048W_CBS1585 | rna-NM_001181706.1_CBS1585 | cds-NP_012582.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:528555-528884:+ | gene-YJR048W_CBS436 | rna-NM_001181706.1_CBS436 | cds-NP_012582.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:497810-498139:+ | gene-YJR048W_CBS6412 | rna-NM_001181706.1_CBS6412 | cds-NP_012582.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:500055-500384:+ | gene-YJR048W_CBS6413 | rna-NM_001181706.1_CBS6413 | cds-NP_012582.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:508700-509029:+ | gene-YJR048W_CENPK1137D | rna-NM_001181706.1_CENPK1137D | cds-NP_012582.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:502937-503266:+ | gene-YJR048W_EthanolRed | rna-NM_001181706.1_EthanolRed | cds-NP_012582.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:514154-514483:+ | gene-YJR048W_FaliES1 | rna-NM_001181706.1_FaliES1 | cds-NP_012582.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000352.1:13938-14267:- | gene-YJR048W_JAY291 | rna-NM_001181706.1_JAY291 | cds-NP_012582.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:512363-512692:+ | gene-YJR048W_MUCL30387 | rna-NM_001181706.1_MUCL30387 | cds-NP_012582.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:508917-509246:+ | gene-YJR048W_MUCL30388 | rna-NM_001181706.1_MUCL30388 | cds-NP_012582.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:503553-503882:+ | gene-YJR048W_MUCL39482 | rna-NM_001181706.1_MUCL39482 | cds-NP_012582.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:508324-508653:+ | gene-YJR048W_MUCL42920 | rna-NM_001181706.1_MUCL42920 | cds-NP_012582.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:526314-526643:+ | gene-YJR048W_NCIM3186 | rna-NM_001181706.1_NCIM3186 | cds-NP_012582.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:501410-501739:+ | gene-YJR048W_NCYC1407 | rna-NM_001181706.1_NCYC1407 | cds-NP_012582.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:519306-519635:+ | gene-YJR048W_PE2H3 | rna-NM_001181706.1_PE2H3 | cds-NP_012582.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:513002-513331:+ | gene-YJR048W_PE2H4 | rna-NM_001181706.1_PE2H4 | cds-NP_012582.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:526335-526664:+ | gene-YJR048W_S288C | rna-NM_001181706.1_S288C | cds-NP_012582.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000110.1:7905-8234:+ | gene-YJR048W_SA1 | rna-NM_001181706.1_SA1 | cds-NP_012582.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:507842-508171:+ | gene-YJR048W_ThermosaccDry | rna-NM_001181706.1_ThermosaccDry | cds-NP_012582.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:510339-510668:+ | gene-YJR048W_VR1 | rna-NM_001181706.1_VR1 | cds-NP_012582.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:487725-488054:+ | gene-YJR048W_ZTW1 | rna-NM_001181706.1_ZTW1 | cds-NP_012582.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:514058-514387:+ | gene-YJR048W_Sparadoxus | rna-NM_001181706.1_Sparadoxus | cds-NP_012582.1_Sparadoxus | 93.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |