CWC25 (YNL245C)


Gene profile

Gene name: CWC25
Reference locus (S288C): YNL245C
Gene biotype: protein_coding

Description: U2-type spliceosomal complex subunit CWC25; Pre-mRNA-splicing factor CWC25; Splicing factor required for the first step of pre-mRNA splicing; binding to the spliceosome requires Prp2p and Yju2p; heat-stable protein; has similarity to S. pombe Cwf25p; Belongs to the CWC25 family

Top 10 interactors (score): CWC2 (0.999); PRP16 (0.999); PRP19 (0.999); SNT309 (0.999); CDC40 (0.999); BUD31 (0.999); YJU2 (0.999); CEF1 (0.999); CWC22 (0.997); BRR2 (0.996); CWC15 (0.996); SNU114 (0.995); SLU7 (0.995); LEA1 (0.995); SYF1 (0.995); PRP18 (0.994); PRP22 (0.991); PRP45 (0.991); CWC24 (0.991); CWC21 (0.99)

Homologues (species, bitscore): CWC25 (Homo sapiens, 59.7); Cwc25 (Mus musculus, 59.7); cwc25 (Danio rerio, 67.8); cwc25 (Xenopus tropicalis, 58.5); Cwc25 (Drosophila melanogaster, 74.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:180131-180670:- gene-YNL245C_AKU4011 rna-NM_001183083.1_AKU4011 cds-NP_014154.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:84075-84614:- gene-YNL245C_BG1 rna-NM_001183083.1_BG1 cds-NP_014154.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:189938-190477:- gene-YNL245C_Bruggeman rna-NM_001183083.1_Bruggeman cds-NP_014154.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:197233-197772:- gene-YNL245C_CAT1 rna-NM_001183083.1_CAT1 cds-NP_014154.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:180528-181067:- gene-YNL245C_CBS1585 rna-NM_001183083.1_CBS1585 cds-NP_014154.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:175618-176157:- gene-YNL245C_CBS436 rna-NM_001183083.1_CBS436 cds-NP_014154.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:176569-177108:- gene-YNL245C_CBS6412 rna-NM_001183083.1_CBS6412 cds-NP_014154.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:177210-177749:- gene-YNL245C_CBS6413 rna-NM_001183083.1_CBS6413 cds-NP_014154.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:180157-180696:- gene-YNL245C_CENPK1137D rna-NM_001183083.1_CENPK1137D cds-NP_014154.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:177788-178327:- gene-YNL245C_EthanolRed rna-NM_001183083.1_EthanolRed cds-NP_014154.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:172523-173062:- gene-YNL245C_FaliES1 rna-NM_001183083.1_FaliES1 cds-NP_014154.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000082.1:83668-84207:- gene-YNL245C_JAY291 rna-NM_001183083.1_JAY291 cds-NP_014154.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:185721-186260:- gene-YNL245C_MUCL30387 rna-NM_001183083.1_MUCL30387 cds-NP_014154.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:184304-184843:- gene-YNL245C_MUCL30388 rna-NM_001183083.1_MUCL30388 cds-NP_014154.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:178018-178557:- gene-YNL245C_MUCL39482 rna-NM_001183083.1_MUCL39482 cds-NP_014154.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:180277-180816:- gene-YNL245C_MUCL42920 rna-NM_001183083.1_MUCL42920 cds-NP_014154.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:186315-186854:- gene-YNL245C_NCIM3186 rna-NM_001183083.1_NCIM3186 cds-NP_014154.1_NCIM3186 99.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:180110-180649:- gene-YNL245C_NCYC1407 rna-NM_001183083.1_NCYC1407 cds-NP_014154.1_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:177011-177550:- gene-YNL245C_PE2H3 rna-NM_001183083.1_PE2H3 cds-NP_014154.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:176399-176938:- gene-YNL245C_PE2H4 rna-NM_001183083.1_PE2H4 cds-NP_014154.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:186346-186885:- gene-YNL245C_S288C rna-NM_001183083.1_S288C cds-NP_014154.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000040.1:65408-65947:+ gene-YNL245C_SA1 rna-NM_001183083.1_SA1 cds-NP_014154.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:173379-173918:- gene-YNL245C_ThermosaccDry rna-NM_001183083.1_ThermosaccDry cds-NP_014154.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:192268-192807:- gene-YNL245C_VR1 rna-NM_001183083.1_VR1 cds-NP_014154.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:83701-84240:- gene-YNL245C_ZTW1 rna-NM_001183083.1_ZTW1 cds-NP_014154.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:183636-184175:- gene-YNL245C_Sparadoxus rna-NM_001183083.1_Sparadoxus cds-NP_014154.1_Sparadoxus 88.7 100.0 Mismatch 1 1 1 False True False False False

Additional files