CWC24 (YLR323C)


Gene profile

Gene name: CWC24
Reference locus (S288C): YLR323C
Gene biotype: protein_coding

Description: Pre-mRNA-splicing factor CWC24; General splicing factor; required for stable U2 snRNP binding to primary transcripts; essential for the first step of splicing; component of the pre-catalytic spliceosome complex containing Cef1p; similar to S. pombe Cwf24p; Belongs to the CWC24 family

Top 10 interactors (score): CEF1 (0.999); PRP19 (0.999); BRR2 (0.998); CDC40 (0.997); BUD31 (0.997); CUS1 (0.995); CWC2 (0.992); CWC22 (0.991); CWC25 (0.991); SNT309 (0.99); PRP2 (0.989); BUD13 (0.988); CWC27 (0.985); PRP11 (0.985); HSH155 (0.983); SLU7 (0.982); ECM2 (0.979); IST3 (0.978); CWC21 (0.977); PML1 (0.975)

Homologues (species, bitscore): RNF113A (Homo sapiens, 144.8); Rnf113a2 (Mus musculus, 146.4); rnf113a (Danio rerio, 150.6); LOC548788 (Xenopus tropicalis, 149.4); mdlc (Drosophila melanogaster, 143.7); rnf-113 (Caenorhabditis elegans, 123.6); AT1G01350 (Arabidopsis thaliana, 140.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:726626-727405:- gene-YLR323C_AKU4011 rna-NM_001182212.1_AKU4011 cds-NP_013427.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000170.1:5276-6055:+ gene-YLR323C_BG1 rna-NM_001182212.1_BG1 cds-NP_013427.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:762459-763238:- gene-YLR323C_Bruggeman rna-NM_001182212.1_Bruggeman cds-NP_013427.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:760615-761394:- gene-YLR323C_CAT1 rna-NM_001182212.1_CAT1 cds-NP_013427.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:761542-762321:- gene-YLR323C_CBS1585 rna-NM_001182212.1_CBS1585 cds-NP_013427.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:746144-746923:- gene-YLR323C_CBS436 rna-NM_001182212.1_CBS436 cds-NP_013427.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:799497-800276:- gene-YLR323C_CBS6412 rna-NM_001182212.1_CBS6412 cds-NP_013427.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:762214-762993:- gene-YLR323C_CBS6413 rna-NM_001182212.1_CBS6413 cds-NP_013427.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:762787-763566:- gene-YLR323C_CENPK1137D rna-NM_001182212.1_CENPK1137D cds-NP_013427.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:719909-720688:- gene-YLR323C_EthanolRed rna-NM_001182212.1_EthanolRed cds-NP_013427.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:749110-749889:- gene-YLR323C_FaliES1 rna-NM_001182212.1_FaliES1 cds-NP_013427.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000296.1:17968-18747:+ gene-YLR323C_JAY291 rna-NM_001182212.1_JAY291 cds-NP_013427.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:761686-762465:- gene-YLR323C_MUCL30387 rna-NM_001182212.1_MUCL30387 cds-NP_013427.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:767271-768050:- gene-YLR323C_MUCL30388 rna-NM_001182212.1_MUCL30388 cds-NP_013427.1_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:762783-763562:- gene-YLR323C_MUCL39482 rna-NM_001182212.1_MUCL39482 cds-NP_013427.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:757935-758714:- gene-YLR323C_MUCL42920 rna-NM_001182212.1_MUCL42920 cds-NP_013427.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:778147-778926:- gene-YLR323C_NCIM3186 rna-NM_001182212.1_NCIM3186 cds-NP_013427.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:772123-772902:- gene-YLR323C_NCYC1407 rna-NM_001182212.1_NCYC1407 cds-NP_013427.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:759907-760686:- gene-YLR323C_PE2H3 rna-NM_001182212.1_PE2H3 cds-NP_013427.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:759651-760430:- gene-YLR323C_PE2H4 rna-NM_001182212.1_PE2H4 cds-NP_013427.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:778173-778952:- gene-YLR323C_S288C rna-NM_001182212.1_S288C cds-NP_013427.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000039.1:5357-6136:+ gene-YLR323C_SA1 rna-NM_001182212.1_SA1 cds-NP_013427.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:751002-751781:- gene-YLR323C_ThermosaccDry rna-NM_001182212.1_ThermosaccDry cds-NP_013427.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:763123-763902:- gene-YLR323C_VR1 rna-NM_001182212.1_VR1 cds-NP_013427.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:89416-90195:- gene-YLR323C_ZTW1 rna-NM_001182212.1_ZTW1 cds-NP_013427.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:737183-737962:- gene-YLR323C_Sparadoxus rna-NM_001182212.1_Sparadoxus cds-NP_013427.1_Sparadoxus 87.0 100.0 Verified 1 1 1 False True False False False

Additional files