Gene name: CWC22
Reference locus (S288C): YGR278W
Gene biotype: protein_coding
Description: U2-type spliceosomal complex subunit CWC22; Pre-mRNA-splicing factor CWC22; Spliceosome-associated protein that is required for pre-mRNA splicing; necessary for Prp2p function at the first catalytic step of splicing; has similarity to S. pombe Cwf22p; CWC22 is an essential protein
Top 10 interactors (score): SNU114 (0.999); PRP19 (0.999); BRR2 (0.999); PRP8 (0.999); CDC40 (0.999); HSH155 (0.999); YJU2 (0.999); CEF1 (0.999); SNT309 (0.999); BUD31 (0.999); PRP22 (0.999); SYF1 (0.999); CWC21 (0.998); PRP45 (0.998); ECM2 (0.998); CLF1 (0.998); SLU7 (0.997); PRP16 (0.997); CWC25 (0.997); FAL1 (0.997)
Homologues (species, bitscore): CWC22 (Homo sapiens, 238.8); Cwc22 (Mus musculus, 245.0); cwc22 (Danio rerio, 244.2); cwc22 (Xenopus tropicalis, 236.9); ncm (Drosophila melanogaster, 225.3); let-858 (Caenorhabditis elegans, 221.9); AT1G80930 (Arabidopsis thaliana, 217.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:1012150-1013883:+ | gene-YGR278W_AKU4011 | rna-NM_001181407.3_AKU4011 | cds-NP_011794.3_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000010.1:2948-4691:+ | gene-YGR278W_BG1 | rna-NM_001181407.3_BG1 | cds-NP_011794.3_BG1 | 98.3 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:1020669-1022412:+ | gene-YGR278W_Bruggeman | rna-NM_001181407.3_Bruggeman | cds-NP_011794.3_Bruggeman | 98.4 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:1020149-1021892:+ | gene-YGR278W_CAT1 | rna-NM_001181407.3_CAT1 | cds-NP_011794.3_CAT1 | 98.3 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:1015018-1016751:+ | gene-YGR278W_CBS1585 | rna-NM_001181407.3_CBS1585 | cds-NP_011794.3_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:1018654-1020397:+ | gene-YGR278W_CBS436 | rna-NM_001181407.3_CBS436 | cds-NP_011794.3_CBS436 | 98.5 | 99.7 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:1005910-1007643:+ | gene-YGR278W_CBS6412 | rna-NM_001181407.3_CBS6412 | cds-NP_011794.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:1011963-1013696:+ | gene-YGR278W_CBS6413 | rna-NM_001181407.3_CBS6413 | cds-NP_011794.3_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:1046462-1048195:+ | gene-YGR278W_CENPK1137D | rna-NM_001181407.3_CENPK1137D | cds-NP_011794.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:999999-1001732:+ | gene-YGR278W_EthanolRed | rna-NM_001181407.3_EthanolRed | cds-NP_011794.3_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:1004805-1006538:+ | gene-YGR278W_FaliES1 | rna-NM_001181407.3_FaliES1 | cds-NP_011794.3_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:23767-25510:- | gene-YGR278W_JAY291 | rna-NM_001181407.3_JAY291 | cds-NP_011794.3_JAY291 | 98.3 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:1018410-1020153:+ | gene-YGR278W_MUCL30387 | rna-NM_001181407.3_MUCL30387 | cds-NP_011794.3_MUCL30387 | 98.5 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:1016542-1018285:+ | gene-YGR278W_MUCL30388 | rna-NM_001181407.3_MUCL30388 | cds-NP_011794.3_MUCL30388 | 98.4 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:1010124-1011857:+ | gene-YGR278W_MUCL39482 | rna-NM_001181407.3_MUCL39482 | cds-NP_011794.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:1028005-1029748:+ | gene-YGR278W_MUCL42920 | rna-NM_001181407.3_MUCL42920 | cds-NP_011794.3_MUCL42920 | 98.4 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:1046731-1048464:+ | gene-YGR278W_NCIM3186 | rna-NM_001181407.3_NCIM3186 | cds-NP_011794.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:1005755-1007488:+ | gene-YGR278W_NCYC1407 | rna-NM_001181407.3_NCYC1407 | cds-NP_011794.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:1030957-1032700:+ | gene-YGR278W_PE2H3 | rna-NM_001181407.3_PE2H3 | cds-NP_011794.3_PE2H3 | 98.5 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:1035796-1037539:+ | gene-YGR278W_PE2H4 | rna-NM_001181407.3_PE2H4 | cds-NP_011794.3_PE2H4 | 98.5 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:1046731-1048464:+ | gene-YGR278W_S288C | rna-NM_001181407.3_S288C | cds-NP_011794.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000063.1:44953-46696:+ | gene-YGR278W_SA1 | rna-NM_001181407.3_SA1 | cds-NP_011794.3_SA1 | 98.3 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:1025325-1027058:+ | gene-YGR278W_ThermosaccDry | rna-NM_001181407.3_ThermosaccDry | cds-NP_011794.3_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1131129-1132869:+ | gene-YGR278W_VR1 | rna-NM_001181407.3_VR1 | cds-NP_011794.3_VR1 | 98.1 | 99.5 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:326731-328464:+ | gene-YGR278W_ZTW1 | rna-NM_001181407.3_ZTW1 | cds-NP_011794.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:1017426-1019159:+ | gene-YGR278W_Sparadoxus | rna-NM_001181407.3_Sparadoxus | cds-NP_011794.3_Sparadoxus | 87.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |