CWC2 (YDL209C)


Gene profile

Gene name: CWC2
Reference locus (S288C): YDL209C
Gene biotype: protein_coding

Description: Pre-mRNA-splicing factor CWC2; Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; binds directly to U6 snRNA; similar to S. pombe Cwf2; Belongs to the RRM CWC2 family

Top 10 interactors (score): SNT309 (0.999); CLF1 (0.999); CDC40 (0.999); SPP2 (0.999); MSL1 (0.999); SMD2 (0.999); CEF1 (0.999); CWC25 (0.999); SMD1 (0.999); BUD13 (0.999); PRP45 (0.999); ECM2 (0.999); PRP46 (0.999); SYF1 (0.999); IST3 (0.999); ISY1 (0.999); BUD31 (0.999); NTC20 (0.999); PRP22 (0.999); CWC21 (0.999)

Homologues (species, bitscore): MAC5A (Arabidopsis thaliana, 60.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:69692-70711:- gene-YDL209C_AKU4011 rna-NM_001180269.1_AKU4011 cds-NP_010072.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000101.1:2866-3885:- gene-YDL209C_BG1 rna-NM_001180269.1_BG1 cds-NP_010072.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:86082-87101:- gene-YDL209C_Bruggeman rna-NM_001180269.1_Bruggeman cds-NP_010072.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:88194-89213:- gene-YDL209C_CAT1 rna-NM_001180269.1_CAT1 cds-NP_010072.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:68544-69563:- gene-YDL209C_CBS1585 rna-NM_001180269.1_CBS1585 cds-NP_010072.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:283447-284466:- gene-YDL209C_CBS436 rna-NM_001180269.1_CBS436 cds-NP_010072.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:68656-69675:- gene-YDL209C_CBS6412 rna-NM_001180269.1_CBS6412 cds-NP_010072.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:86202-87221:- gene-YDL209C_CBS6413 rna-NM_001180269.1_CBS6413 cds-NP_010072.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:84873-85892:- gene-YDL209C_CENPK1137D rna-NM_001180269.1_CENPK1137D cds-NP_010072.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:82340-83359:- gene-YDL209C_EthanolRed rna-NM_001180269.1_EthanolRed cds-NP_010072.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:86945-87964:- gene-YDL209C_FaliES1 rna-NM_001180269.1_FaliES1 cds-NP_010072.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000344.1:31288-32307:+ gene-YDL209C_JAY291 rna-NM_001180269.1_JAY291 cds-NP_010072.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:84315-85334:- gene-YDL209C_MUCL30387 rna-NM_001180269.1_MUCL30387 cds-NP_010072.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:73886-74905:- gene-YDL209C_MUCL30388 rna-NM_001180269.1_MUCL30388 cds-NP_010072.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:69387-70406:- gene-YDL209C_MUCL39482 rna-NM_001180269.1_MUCL39482 cds-NP_010072.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:85466-86485:- gene-YDL209C_MUCL42920 rna-NM_001180269.1_MUCL42920 cds-NP_010072.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:86130-87149:- gene-YDL209C_NCIM3186 rna-NM_001180269.1_NCIM3186 cds-NP_010072.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:69343-70362:- gene-YDL209C_NCYC1407 rna-NM_001180269.1_NCYC1407 cds-NP_010072.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:77086-78105:- gene-YDL209C_PE2H3 rna-NM_001180269.1_PE2H3 cds-NP_010072.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:77096-78115:- gene-YDL209C_PE2H4 rna-NM_001180269.1_PE2H4 cds-NP_010072.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:86207-87226:- gene-YDL209C_S288C rna-NM_001180269.1_S288C cds-NP_010072.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000126.1:2776-3795:- gene-YDL209C_SA1 rna-NM_001180269.1_SA1 cds-NP_010072.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:86709-87728:- gene-YDL209C_ThermosaccDry rna-NM_001180269.1_ThermosaccDry cds-NP_010072.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:87661-88680:- gene-YDL209C_VR1 rna-NM_001180269.1_VR1 cds-NP_010072.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:85388-86407:- gene-YDL209C_ZTW1 rna-NM_001180269.1_ZTW1 cds-NP_010072.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:88721-89746:- gene-YDL209C_Sparadoxus rna-NM_001180269.1_Sparadoxus cds-NP_010072.1_Sparadoxus 87.2 100.0 Verified 1 1 1 False True False False False

Additional files