Gene name: CUZ1
Reference locus (S288C): YNL155W
Gene biotype: protein_coding
Description: CDC48-associated ubiquitin-like/zinc finger protein 1; Protein with a role in the ubiquitin-proteasome pathway; interacts with ubiquitinated protein, Cdc48p and the proteasomal regulatory particle; may protect cells from trivalent metalloid induced proteotoxicity; contains a PACE promoter element and is co-regulated with proteasome subunit genes; AN1-type zinc finger protein, with DHHC and ubiquitin-like domains (UBL); ortholog of ZFAND1, a human gene linked to cancer; protein abundance increases under DNA replication stress
Top 10 interactors (score): CDC48 (0.944); NPL4 (0.794); RPN8 (0.748); SHP1 (0.747); RPN2 (0.736); MCH1 (0.699); BSC2 (0.696); MUM3 (0.691); MBF1 (0.684); UFD1 (0.684); PUF3 (0.673); TMC1 (0.647); RPN7 (0.632); SNU13 (0.613); RPN11 (0.612); UBI4 (0.612); GDE1 (0.597); THR4 (0.595); APC4 (0.593); PRE8 (0.583)
Homologues (species, bitscore): ZFAND1 (Homo sapiens, 76.6); Zfand1 (Mus musculus, 73.6); zfand1 (Danio rerio, 72.8); zfand1 (Xenopus tropicalis, 80.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:336229-337053:+ | gene-YNL155W_AKU4011 | rna-NM_001182993.1_AKU4011 | cds-NP_014244.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:240256-241080:+ | gene-YNL155W_BG1 | rna-NM_001182993.1_BG1 | cds-NP_014244.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:346294-347118:+ | gene-YNL155W_Bruggeman | rna-NM_001182993.1_Bruggeman | cds-NP_014244.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:389222-390046:+ | gene-YNL155W_CAT1 | rna-NM_001182993.1_CAT1 | cds-NP_014244.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:336879-337703:+ | gene-YNL155W_CBS1585 | rna-NM_001182993.1_CBS1585 | cds-NP_014244.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:405237-406061:+ | gene-YNL155W_CBS436 | rna-NM_001182993.1_CBS436 | cds-NP_014244.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:332285-333109:+ | gene-YNL155W_CBS6412 | rna-NM_001182993.1_CBS6412 | cds-NP_014244.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:333313-334137:+ | gene-YNL155W_CBS6413 | rna-NM_001182993.1_CBS6413 | cds-NP_014244.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:336330-337154:+ | gene-YNL155W_CENPK1137D | rna-NM_001182993.1_CENPK1137D | cds-NP_014244.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:333211-334035:+ | gene-YNL155W_EthanolRed | rna-NM_001182993.1_EthanolRed | cds-NP_014244.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:329124-329948:+ | gene-YNL155W_FaliES1 | rna-NM_001182993.1_FaliES1 | cds-NP_014244.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000439.1:13701-14525:- | gene-YNL155W_JAY291 | rna-NM_001182993.1_JAY291 | cds-NP_014244.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:342115-342939:+ | gene-YNL155W_MUCL30387 | rna-NM_001182993.1_MUCL30387 | cds-NP_014244.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:376669-377493:+ | gene-YNL155W_MUCL30388 | rna-NM_001182993.1_MUCL30388 | cds-NP_014244.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:334119-334943:+ | gene-YNL155W_MUCL39482 | rna-NM_001182993.1_MUCL39482 | cds-NP_014244.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:336523-337347:+ | gene-YNL155W_MUCL42920 | rna-NM_001182993.1_MUCL42920 | cds-NP_014244.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:342485-343309:+ | gene-YNL155W_NCIM3186 | rna-NM_001182993.1_NCIM3186 | cds-NP_014244.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:336213-337037:+ | gene-YNL155W_NCYC1407 | rna-NM_001182993.1_NCYC1407 | cds-NP_014244.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:333207-334031:+ | gene-YNL155W_PE2H3 | rna-NM_001182993.1_PE2H3 | cds-NP_014244.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:332595-333419:+ | gene-YNL155W_PE2H4 | rna-NM_001182993.1_PE2H4 | cds-NP_014244.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:342516-343340:+ | gene-YNL155W_S288C | rna-NM_001182993.1_S288C | cds-NP_014244.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:70211-71035:- | gene-YNL155W_SA1 | rna-NM_001182993.1_SA1 | cds-NP_014244.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:329981-330805:+ | gene-YNL155W_ThermosaccDry | rna-NM_001182993.1_ThermosaccDry | cds-NP_014244.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:348536-349360:+ | gene-YNL155W_VR1 | rna-NM_001182993.1_VR1 | cds-NP_014244.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:239803-240627:+ | gene-YNL155W_ZTW1 | rna-NM_001182993.1_ZTW1 | cds-NP_014244.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:340629-341453:+ | gene-YNL155W_Sparadoxus | rna-NM_001182993.1_Sparadoxus | cds-NP_014244.1_Sparadoxus | 86.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |