Gene name: CUR1
Reference locus (S288C): YPR158W
Gene biotype: protein_coding
Description: Curing of [URE3] protein 1; Sorting factor, central regulator of spatial protein quality control; physically and functionally interacts with chaperones to promote sorting and deposition of misfolded proteins into cytosolic compartments; involved in destabilization of [URE3] prions; CUR1 has a paralog, BTN2, that arose from the whole genome duplication
Top 10 interactors (score): SIS1 (0.984); HSP42 (0.976); BTN2 (0.967); FES1 (0.894); HSP104 (0.86); URE2 (0.813); YDJ1 (0.812); AHA1 (0.751); SIW14 (0.748); STI1 (0.738); HSP78 (0.728); OPI10 (0.728); SUP35 (0.692); RNQ1 (0.691); HSP82 (0.69); HSC82 (0.651); SSE1 (0.65); YJL144W (0.631); CPR6 (0.62); APJ1 (0.594)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:809398-810156:+ | gene-YPR158W_AKU4011 | rna-NM_001184255.1_AKU4011 | cds-NP_015484.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:87216-87974:- | gene-YPR158W_BG1 | rna-NM_001184255.1_BG1 | cds-NP_015484.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:889935-890693:+ | gene-YPR158W_Bruggeman | rna-NM_001184255.1_Bruggeman | cds-NP_015484.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:931949-932707:+ | gene-YPR158W_CAT1 | rna-NM_001184255.1_CAT1 | cds-NP_015484.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:814198-814956:+ | gene-YPR158W_CBS1585 | rna-NM_001184255.1_CBS1585 | cds-NP_015484.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:827759-828517:+ | gene-YPR158W_CBS436 | rna-NM_001184255.1_CBS436 | cds-NP_015484.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:816062-816820:+ | gene-YPR158W_CBS6412 | rna-NM_001184255.1_CBS6412 | cds-NP_015484.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:811127-811885:+ | gene-YPR158W_CBS6413 | rna-NM_001184255.1_CBS6413 | cds-NP_015484.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:843272-844030:+ | gene-YPR158W_CENPK1137D | rna-NM_001184255.1_CENPK1137D | cds-NP_015484.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1131380-1132138:+ | gene-YPR158W_EthanolRed | rna-NM_001184255.1_EthanolRed | cds-NP_015484.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:811086-811844:+ | gene-YPR158W_FaliES1 | rna-NM_001184255.1_FaliES1 | cds-NP_015484.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000251.1:4187-4945:+ | gene-YPR158W_JAY291 | rna-NM_001184255.1_JAY291 | cds-NP_015484.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:858023-858781:+ | gene-YPR158W_MUCL30387 | rna-NM_001184255.1_MUCL30387 | cds-NP_015484.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:830603-831361:+ | gene-YPR158W_MUCL30388 | rna-NM_001184255.1_MUCL30388 | cds-NP_015484.1_MUCL30388 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:806401-807159:+ | gene-YPR158W_MUCL39482 | rna-NM_001184255.1_MUCL39482 | cds-NP_015484.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:870412-871170:+ | gene-YPR158W_MUCL42920 | rna-NM_001184255.1_MUCL42920 | cds-NP_015484.1_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:843245-844003:+ | gene-YPR158W_NCIM3186 | rna-NM_001184255.1_NCIM3186 | cds-NP_015484.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:814761-815519:+ | gene-YPR158W_NCYC1407 | rna-NM_001184255.1_NCYC1407 | cds-NP_015484.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:821479-822237:+ | gene-YPR158W_PE2H3 | rna-NM_001184255.1_PE2H3 | cds-NP_015484.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:821127-821885:+ | gene-YPR158W_PE2H4 | rna-NM_001184255.1_PE2H4 | cds-NP_015484.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:843262-844020:+ | gene-YPR158W_S288C | rna-NM_001184255.1_S288C | cds-NP_015484.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000060.1:69934-70692:- | gene-YPR158W_SA1 | rna-NM_001184255.1_SA1 | cds-NP_015484.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:810774-811532:+ | gene-YPR158W_ThermosaccDry | rna-NM_001184255.1_ThermosaccDry | cds-NP_015484.1_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:832964-833722:+ | gene-YPR158W_VR1 | rna-NM_001184255.1_VR1 | cds-NP_015484.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:813900-814658:+ | gene-YPR158W_ZTW1 | rna-NM_001184255.1_ZTW1 | cds-NP_015484.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:815821-816580:+ | gene-YPR158W_Sparadoxus | rna-NM_001184255.1_Sparadoxus | cds-NP_015484.1_Sparadoxus | 83.8 | 99.6 | Verified | 1 | 1 | 0 | False | False | False | True | False |