Gene name: CUP2
Reference locus (S288C): YGL166W
Gene biotype: protein_coding
Description: Transcriptional activator protein CUP2; Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations; required for regulation of copper genes in response to DNA-damaging reagents; CUP2 has a paralog, HAA1, that arose from the whole genome duplication
Top 10 interactors (score): CUP1-2 (0.916); CTR3 (0.913); CUP1-1 (0.91); CRS5 (0.897); CTR2 (0.815); SOD1 (0.745); FET3 (0.736); MNC1 (0.733); FRE1 (0.694); ATX1 (0.68); CCC2 (0.675); FRE7 (0.623); IRC7 (0.619); YBR085C-A (0.599); AFT1 (0.574); ZAP1 (0.574); REE1 (0.572); NIT2 (0.572); YBR200W-A (0.571); YDR210W-B (0.571)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:193698-194375:+ | gene-YGL166W_AKU4011 | rna-NM_001181031.3_AKU4011 | cds-NP_011349.3_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:215985-216662:- | gene-YGL166W_BG1 | rna-NM_001181031.3_BG1 | cds-NP_011349.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:195861-196538:+ | gene-YGL166W_Bruggeman | rna-NM_001181031.3_Bruggeman | cds-NP_011349.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:191731-192408:+ | gene-YGL166W_CAT1 | rna-NM_001181031.3_CAT1 | cds-NP_011349.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:196837-197514:+ | gene-YGL166W_CBS1585 | rna-NM_001181031.3_CBS1585 | cds-NP_011349.3_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:191721-192398:+ | gene-YGL166W_CBS436 | rna-NM_001181031.3_CBS436 | cds-NP_011349.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:183300-183977:+ | gene-YGL166W_CBS6412 | rna-NM_001181031.3_CBS6412 | cds-NP_011349.3_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:191149-191826:+ | gene-YGL166W_CBS6413 | rna-NM_001181031.3_CBS6413 | cds-NP_011349.3_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:191391-192068:+ | gene-YGL166W_CENPK1137D | rna-NM_001181031.3_CENPK1137D | cds-NP_011349.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:183505-184182:+ | gene-YGL166W_EthanolRed | rna-NM_001181031.3_EthanolRed | cds-NP_011349.3_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:184751-185428:+ | gene-YGL166W_FaliES1 | rna-NM_001181031.3_FaliES1 | cds-NP_011349.3_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000090.1:34954-35631:+ | gene-YGL166W_JAY291 | rna-NM_001181031.3_JAY291 | cds-NP_011349.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:193109-193786:+ | gene-YGL166W_MUCL30387 | rna-NM_001181031.3_MUCL30387 | cds-NP_011349.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:196199-196876:+ | gene-YGL166W_MUCL30388 | rna-NM_001181031.3_MUCL30388 | cds-NP_011349.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:193861-194538:+ | gene-YGL166W_MUCL39482 | rna-NM_001181031.3_MUCL39482 | cds-NP_011349.3_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:196449-197126:+ | gene-YGL166W_MUCL42920 | rna-NM_001181031.3_MUCL42920 | cds-NP_011349.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:191129-191806:+ | gene-YGL166W_NCIM3186 | rna-NM_001181031.3_NCIM3186 | cds-NP_011349.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:185327-186004:+ | gene-YGL166W_NCYC1407 | rna-NM_001181031.3_NCYC1407 | cds-NP_011349.3_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:187255-187932:+ | gene-YGL166W_PE2H3 | rna-NM_001181031.3_PE2H3 | cds-NP_011349.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:186803-187480:+ | gene-YGL166W_PE2H4 | rna-NM_001181031.3_PE2H4 | cds-NP_011349.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:191129-191806:+ | gene-YGL166W_S288C | rna-NM_001181031.3_S288C | cds-NP_011349.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000067.1:50913-51590:+ | gene-YGL166W_SA1 | rna-NM_001181031.3_SA1 | cds-NP_011349.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:184980-185657:+ | gene-YGL166W_ThermosaccDry | rna-NM_001181031.3_ThermosaccDry | cds-NP_011349.3_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:192157-192834:+ | gene-YGL166W_VR1 | rna-NM_001181031.3_VR1 | cds-NP_011349.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:183430-184107:+ | gene-YGL166W_ZTW1 | rna-NM_001181031.3_ZTW1 | cds-NP_011349.3_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:190315-190992:+ | gene-YGL166W_Sparadoxus | rna-NM_001181031.3_Sparadoxus | cds-NP_011349.3_Sparadoxus | 85.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |