Gene name: CUP1-2
Reference locus (S288C): YHR055C
Gene biotype: protein_coding
Description: Metallothionein; binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C; CUP1-2 has a paralog, CUP1-1, that arose from a segmental duplication
Top 10 interactors (score): CUP1-1 (0.973); CUP2 (0.916); CRS5 (0.89); URA3 (0.87); SOD1 (0.855); GAL1 (0.81); CTR3 (0.806); SUP35 (0.79); LEU2 (0.766); CTR2 (0.757); CCC2 (0.727); FRE1 (0.719); SUC2 (0.718); PGK1 (0.718); RNQ1 (0.718); HIS3 (0.717); TRP1 (0.717); ASP3-4 (0.698); GAL2 (0.697); ADE2 (0.695)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:200797-200982:- | gene-YHR055C_AKU4011 | rna-NM_001179183.1_AKU4011 | cds-NP_011920.1_AKU4011 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:121937-122122:- | gene-YHR055C_BG1 | rna-NM_001179183.1_BG1 | cds-NP_011920.1_BG1 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:208549-208734:- | gene-YHR055C_Bruggeman | rna-NM_001179183.1_Bruggeman | cds-NP_011920.1_Bruggeman | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:203343-203528:- | gene-YHR055C_CAT1 | rna-NM_001179183.1_CAT1 | cds-NP_011920.1_CAT1 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:199903-200088:- | gene-YHR055C_CBS1585 | rna-NM_001179183.1_CBS1585 | cds-NP_011920.1_CBS1585 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:195660-195845:- | gene-YHR055C_CBS436 | rna-NM_001179183.1_CBS436 | cds-NP_011920.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:200135-200320:- | gene-YHR055C_CBS6412 | rna-NM_001179183.1_CBS6412 | cds-NP_011920.1_CBS6412 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:200967-201152:- | gene-YHR055C_CBS6413 | rna-NM_001179183.1_CBS6413 | cds-NP_011920.1_CBS6413 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:200294-200479:- | gene-YHR055C_EthanolRed | rna-NM_001179183.1_EthanolRed | cds-NP_011920.1_EthanolRed | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:201271-201456:- | gene-YHR055C_FaliES1 | rna-NM_001179183.1_FaliES1 | cds-NP_011920.1_FaliES1 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000330.1:479-664:- | gene-YHR055C_JAY291 | rna-NM_001179183.1_JAY291 | cds-NP_011920.1_JAY291 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:208008-208193:- | gene-YHR055C_MUCL30387 | rna-NM_001179183.1_MUCL30387 | cds-NP_011920.1_MUCL30387 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:208184-208369:- | gene-YHR055C_MUCL30388 | rna-NM_001179183.1_MUCL30388 | cds-NP_011920.1_MUCL30388 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:200188-200373:- | gene-YHR055C_MUCL39482 | rna-NM_001179183.1_MUCL39482 | cds-NP_011920.1_MUCL39482 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:207092-207277:- | gene-YHR055C_MUCL42920 | rna-NM_001179183.1_MUCL42920 | cds-NP_011920.1_MUCL42920 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:214415-214600:- | gene-YHR055C_NCIM3186 | rna-NM_001179183.1_NCIM3186 | cds-NP_011920.1_NCIM3186 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:200452-200637:- | gene-YHR055C_NCYC1407 | rna-NM_001179183.1_NCYC1407 | cds-NP_011920.1_NCYC1407 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:202390-202575:- | gene-YHR055C_PE2H3 | rna-NM_001179183.1_PE2H3 | cds-NP_011920.1_PE2H3 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:209837-210022:- | gene-YHR055C_PE2H4 | rna-NM_001179183.1_PE2H4 | cds-NP_011920.1_PE2H4 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:214533-214718:- | gene-YHR055C_S288C | rna-NM_001179183.1_S288C | cds-NP_011920.1_S288C | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:144714-144899:+ | gene-YHR055C_SA1 | rna-NM_001179183.1_SA1 | cds-NP_011920.1_SA1 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:202362-202547:- | gene-YHR055C_ThermosaccDry | rna-NM_001179183.1_ThermosaccDry | cds-NP_011920.1_ThermosaccDry | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:209143-209328:- | gene-YHR055C_VR1 | rna-NM_001179183.1_VR1 | cds-NP_011920.1_VR1 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:193915-194100:- | gene-YHR055C_ZTW1 | rna-NM_001179183.1_ZTW1 | cds-NP_011920.1_ZTW1 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |