Gene name: CUP1-1
Reference locus (S288C): YHR053C
Gene biotype: protein_coding
Description: Metallothionein; binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C; CUP1-1 has a paralog, CUP1-2, that arose from a segmental duplication
Top 10 interactors (score): CUP1-2 (0.973); CUP2 (0.91); CRS5 (0.907); SOD1 (0.892); URA3 (0.87); GAL1 (0.812); CTR3 (0.782); LEU2 (0.765); SUP35 (0.749); PGK1 (0.744); TRP1 (0.718); RNQ1 (0.717); HIS3 (0.716); SUC2 (0.715); FRE1 (0.715); GAL2 (0.697); ADE2 (0.696); TDH3 (0.678); ADE1 (0.677); CTR2 (0.676)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:121052-121237:- | gene-YHR053C_BG1 | rna-NM_001179185.1_BG1 | cds-NP_011922.1_BG1 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | JH711432.1:1534-1719:+ | gene-YHR053C_CENPK1137D | rna-NM_001179185.1_CENPK1137D | cds-NP_011922.1_CENPK1137D | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:212417-212602:- | gene-YHR053C_NCIM3186 | rna-NM_001179185.1_NCIM3186 | cds-NP_011922.1_NCIM3186 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:212535-212720:- | gene-YHR053C_S288C | rna-NM_001179185.1_S288C | cds-NP_011922.1_S288C | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:145875-146060:+ | gene-YHR053C_SA1 | rna-NM_001179185.1_SA1 | cds-NP_011922.1_SA1 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:199423-199605:- | gene-YHR053C_Sparadoxus | rna-NM_001179185.1_Sparadoxus | cds-NP_011922.1_Sparadoxus | 90.3 | 98.3 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |