Gene name: CUL3
Reference locus (S288C): YGR003W
Gene biotype: protein_coding
Description: Cullin-3; Ubiquitin-protein ligase; forms a complex with Elc1p that polyubiquitylates monoubiquitylated RNA polymerase II to trigger its proteolysis; cullin family member with similarity to Cdc53p and human CUL3; Belongs to the cullin family
Top 10 interactors (score): ELC1 (0.999); HRT1 (0.999); RRI1 (0.999); SKP1 (0.999); UBC12 (0.998); DCN1 (0.997); CDC53 (0.99); UBA3 (0.987); RAD7 (0.985); RAD16 (0.971); YIL001W (0.965); APC11 (0.961); ELA1 (0.956); UBX5 (0.944); ULA1 (0.938); UBA1 (0.93); RUB1 (0.925); SEC31 (0.921); RSP5 (0.902); CDC4 (0.87)
Homologues (species, bitscore): CUL3 (Homo sapiens, 219.5); Cul3 (Mus musculus, 219.2); cul3a (Danio rerio, 214.9); cul3 (Xenopus tropicalis, 214.5); Cul3 (Drosophila melanogaster, 194.1); cul-3 (Caenorhabditis elegans, 183.3); CUL3 (Arabidopsis thaliana, 209.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:502179-504413:+ | gene-YGR003W_AKU4011 | rna-NM_001181132.1_AKU4011 | cds-NP_011517.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:71696-73930:- | gene-YGR003W_BG1 | rna-NM_001181132.1_BG1 | cds-NP_011517.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:503148-505382:+ | gene-YGR003W_Bruggeman | rna-NM_001181132.1_Bruggeman | cds-NP_011517.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:501942-504176:+ | gene-YGR003W_CAT1 | rna-NM_001181132.1_CAT1 | cds-NP_011517.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:503672-505906:+ | gene-YGR003W_CBS1585 | rna-NM_001181132.1_CBS1585 | cds-NP_011517.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:498035-500269:+ | gene-YGR003W_CBS436 | rna-NM_001181132.1_CBS436 | cds-NP_011517.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:496268-498502:+ | gene-YGR003W_CBS6412 | rna-NM_001181132.1_CBS6412 | cds-NP_011517.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:500345-502579:+ | gene-YGR003W_CBS6413 | rna-NM_001181132.1_CBS6413 | cds-NP_011517.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:499950-502184:+ | gene-YGR003W_CENPK1137D | rna-NM_001181132.1_CENPK1137D | cds-NP_011517.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:490550-492784:+ | gene-YGR003W_EthanolRed | rna-NM_001181132.1_EthanolRed | cds-NP_011517.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:493800-496034:+ | gene-YGR003W_FaliES1 | rna-NM_001181132.1_FaliES1 | cds-NP_011517.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000020.1:32434-34668:+ | gene-YGR003W_JAY291 | rna-NM_001181132.1_JAY291 | cds-NP_011517.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:500370-502604:+ | gene-YGR003W_MUCL30387 | rna-NM_001181132.1_MUCL30387 | cds-NP_011517.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:502921-505155:+ | gene-YGR003W_MUCL30388 | rna-NM_001181132.1_MUCL30388 | cds-NP_011517.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:499491-501725:+ | gene-YGR003W_MUCL39482 | rna-NM_001181132.1_MUCL39482 | cds-NP_011517.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:508922-511156:+ | gene-YGR003W_MUCL42920 | rna-NM_001181132.1_MUCL42920 | cds-NP_011517.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:500132-502366:+ | gene-YGR003W_NCIM3186 | rna-NM_001181132.1_NCIM3186 | cds-NP_011517.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:493532-495766:+ | gene-YGR003W_NCYC1407 | rna-NM_001181132.1_NCYC1407 | cds-NP_011517.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:496202-498436:+ | gene-YGR003W_PE2H3 | rna-NM_001181132.1_PE2H3 | cds-NP_011517.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:501252-503486:+ | gene-YGR003W_PE2H4 | rna-NM_001181132.1_PE2H4 | cds-NP_011517.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:500132-502366:+ | gene-YGR003W_S288C | rna-NM_001181132.1_S288C | cds-NP_011517.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:53221-55455:- | gene-YGR003W_SA1 | rna-NM_001181132.1_SA1 | cds-NP_011517.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:513126-515360:+ | gene-YGR003W_ThermosaccDry | rna-NM_001181132.1_ThermosaccDry | cds-NP_011517.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:603418-605652:+ | gene-YGR003W_VR1 | rna-NM_001181132.1_VR1 | cds-NP_011517.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:491724-493958:+ | gene-YGR003W_ZTW1 | rna-NM_001181132.1_ZTW1 | cds-NP_011517.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:501212-503446:+ | gene-YGR003W_Sparadoxus | rna-NM_001181132.1_Sparadoxus | cds-NP_011517.1_Sparadoxus | 87.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |