Gene name: CUE1
Reference locus (S288C): YMR264W
Gene biotype: protein_coding
Description: Coupling of ubiquitin conjugation to ER degradation protein 1; Ubiquitin-binding protein; ER membrane protein that recruits and integrates the ubiquitin-conjugating enzyme Ubc7p into ER membrane-bound ubiquitin ligase complexes that function in the ER-associated degradation (ERAD) pathway for misfolded proteins; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination and to promote diubiquitin elongation, facilitating polyubiquitin chain formation
Top 10 interactors (score): UBC7 (0.999); SSM4 (0.999); USA1 (0.995); HRD1 (0.994); HRD3 (0.993); UBX2 (0.991); DER1 (0.99); NPL4 (0.99); CDC48 (0.986); UFD1 (0.985); SEC61 (0.9); YOS9 (0.897); UBC6 (0.778); MNL1 (0.75); UBC1 (0.744); KAR2 (0.742); CUE2 (0.697); UFD2 (0.692); HAC1 (0.684); ASI3 (0.678)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:835260-835871:+ | gene-YMR264W_AKU4011 | rna-NM_001182771.1_AKU4011 | cds-NP_013991.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:118546-119157:- | gene-YMR264W_BG1 | rna-NM_001182771.1_BG1 | cds-NP_013991.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:780474-781085:+ | gene-YMR264W_Bruggeman | rna-NM_001182771.1_Bruggeman | cds-NP_013991.1_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:783496-784107:+ | gene-YMR264W_CAT1 | rna-NM_001182771.1_CAT1 | cds-NP_013991.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:767510-768121:+ | gene-YMR264W_CBS1585 | rna-NM_001182771.1_CBS1585 | cds-NP_013991.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:789442-790053:+ | gene-YMR264W_CBS436 | rna-NM_001182771.1_CBS436 | cds-NP_013991.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:879065-879676:+ | gene-YMR264W_CBS6412 | rna-NM_001182771.1_CBS6412 | cds-NP_013991.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:766612-767223:+ | gene-YMR264W_CBS6413 | rna-NM_001182771.1_CBS6413 | cds-NP_013991.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:790214-790825:+ | gene-YMR264W_CENPK1137D | rna-NM_001182771.1_CENPK1137D | cds-NP_013991.1_CENPK1137D | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:827954-828565:+ | gene-YMR264W_EthanolRed | rna-NM_001182771.1_EthanolRed | cds-NP_013991.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:773981-774592:+ | gene-YMR264W_FaliES1 | rna-NM_001182771.1_FaliES1 | cds-NP_013991.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:11946-12557:- | gene-YMR264W_JAY291 | rna-NM_001182771.1_JAY291 | cds-NP_013991.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:774323-774934:+ | gene-YMR264W_MUCL30387 | rna-NM_001182771.1_MUCL30387 | cds-NP_013991.1_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:782916-783527:+ | gene-YMR264W_MUCL30388 | rna-NM_001182771.1_MUCL30388 | cds-NP_013991.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:768598-769209:+ | gene-YMR264W_MUCL39482 | rna-NM_001182771.1_MUCL39482 | cds-NP_013991.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:776651-777262:+ | gene-YMR264W_MUCL42920 | rna-NM_001182771.1_MUCL42920 | cds-NP_013991.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:795759-796370:+ | gene-YMR264W_NCIM3186 | rna-NM_001182771.1_NCIM3186 | cds-NP_013991.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:768222-768833:+ | gene-YMR264W_NCYC1407 | rna-NM_001182771.1_NCYC1407 | cds-NP_013991.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:778216-778827:+ | gene-YMR264W_PE2H3 | rna-NM_001182771.1_PE2H3 | cds-NP_013991.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:779262-779873:+ | gene-YMR264W_PE2H4 | rna-NM_001182771.1_PE2H4 | cds-NP_013991.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:795805-796416:+ | gene-YMR264W_S288C | rna-NM_001182771.1_S288C | cds-NP_013991.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:12018-12629:- | gene-YMR264W_SA1 | rna-NM_001182771.1_SA1 | cds-NP_013991.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:770150-770761:+ | gene-YMR264W_ThermosaccDry | rna-NM_001182771.1_ThermosaccDry | cds-NP_013991.1_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:782752-783363:+ | gene-YMR264W_VR1 | rna-NM_001182771.1_VR1 | cds-NP_013991.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:185344-185955:+ | gene-YMR264W_ZTW1 | rna-NM_001182771.1_ZTW1 | cds-NP_013991.1_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:788486-789097:+ | gene-YMR264W_Sparadoxus | rna-NM_001182771.1_Sparadoxus | cds-NP_013991.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |